BacMap

Definition	Bacillus anthracis str. Sterne chromosome, complete genome.
Accession	NC_005945
Length	5,228,663

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The map label for this gene is yxlF [H]

Identifier: 49187639

GI number: 49187639

Start: 4543055

End: 4543888

Strand: Direct

Name: yxlF [H]

Synonym: BAS4648

Alternate gene names: 49187639

Gene position: 4543055-4543888 (Clockwise)

Preceding gene: 49187638

Following gene: 49187640

Centisome position: 86.89

GC content: 34.77

Gene sequence:

>834_bases
TTGCTAGTAGAACTAAGGGGAATTCAAAAGAAATATGGCAAATCACTTATACTAGACAACATTGATTTATCCATTCCAGA
AGGAGAAGCACTGGCTATTATCGGCGGGAACGGGACTGGAAAAAGTACTCTACTCAAAATAATTGCAGGTTTTATTTCAC
CTACGGCAGGGACAATTCAAAGAAAAGAACATATACAAATCGGTTATGTACCTGAACATTTTCCTGAAGGGATTCGTTTT
ACATTAGAGGATTATCTATACCATCTCGGCCACATTCACGGTTTATCAACAAAATATGTAAAAGATAAAATTCCGATGCT
TCTGGAATCTTTTCATTTACATCATGCAAGACATTCTGTTGTACGAAACTTTTCAAAGGGCATGAAACAAAAAACAGGTA
TTATGCAAGCATTACTTACGGACGTACATTTATTAATTTTGGACGAACCCCTTTCTGGACTCGATCCTAACTCTCAGCAA
GAATTAGAACATATTTTACTCTCATTAAAACAACAAGGTATATCCGTGTTATTTACATGTCACGAAAAACAACTATTAGA
AAACTTCGCTGATAGAATTGTGACGTTAGCAAATCATACAATCACAGAAAATATCTCTGCACAAAAAGGAGCAGAGCGGG
TCTATATTGAAGCAATCGTTCACGAAACATTTTCAGCGATAGAACTACAAAAACAATCCGGTTTTATACACGTTGCACAC
AATTCAAATCAAAACCTTATTCAATTGCACATCGAAAAAGAACATACAAATGACATACTTCAGTTTTTATTACATAAAAA
AGCATCTATCACACTGCTACAACCTAACTTTTAA

Upstream 100 bases:

>100_bases
ACAAAAGATAACAAAAAAAGACGTGCGCTCATTGCACGTCTTTTTGTTATTCTCCTATATAATGGATATATACAATATTC
GAAGAAAGAAGGATAGAACT

Downstream 100 bases:

>100_bases
ATCGAAAGAAGGTTTATTATGTTTGCTCTTATTCGTTATCACTTTCTCGACTATACAAAATCGTATAAGTACGTCCCTCC
TATTGCGATGTACTTCATGA

Product: ABC transporter ATP-binding protein

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MLVELRGIQKKYGKSLILDNIDLSIPEGEALAIIGGNGTGKSTLLKIIAGFISPTAGTIQRKEHIQIGYVPEHFPEGIRF
TLEDYLYHLGHIHGLSTKYVKDKIPMLLESFHLHHARHSVVRNFSKGMKQKTGIMQALLTDVHLLILDEPLSGLDPNSQQ
ELEHILLSLKQQGISVLFTCHEKQLLENFADRIVTLANHTITENISAQKGAERVYIEAIVHETFSAIELQKQSGFIHVAH
NSNQNLIQLHIEKEHTNDILQFLLHKKASITLLQPNF

Sequences:

>Translated_277_residues
MLVELRGIQKKYGKSLILDNIDLSIPEGEALAIIGGNGTGKSTLLKIIAGFISPTAGTIQRKEHIQIGYVPEHFPEGIRF
TLEDYLYHLGHIHGLSTKYVKDKIPMLLESFHLHHARHSVVRNFSKGMKQKTGIMQALLTDVHLLILDEPLSGLDPNSQQ
ELEHILLSLKQQGISVLFTCHEKQLLENFADRIVTLANHTITENISAQKGAERVYIEAIVHETFSAIELQKQSGFIHVAH
NSNQNLIQLHIEKEHTNDILQFLLHKKASITLLQPNF
>Mature_277_residues
MLVELRGIQKKYGKSLILDNIDLSIPEGEALAIIGGNGTGKSTLLKIIAGFISPTAGTIQRKEHIQIGYVPEHFPEGIRF
TLEDYLYHLGHIHGLSTKYVKDKIPMLLESFHLHHARHSVVRNFSKGMKQKTGIMQALLTDVHLLILDEPLSGLDPNSQQ
ELEHILLSLKQQGISVLFTCHEKQLLENFADRIVTLANHTITENISAQKGAERVYIEAIVHETFSAIELQKQSGFIHVAH
NSNQNLIQLHIEKEHTNDILQFLLHKKASITLLQPNF

Specific function: Part Of The Abc Transporter Complex Cysawtp Involved In Sulfate/Thiosulfate Import. Responsible For Energy Coupling To The Transport System. [C]

COG id: COG1131

COG function: function code V; ABC-type multidrug transport system, ATPase component

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27881501, Length=212, Percent_Identity=31.1320754716981, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI30795238, Length=212, Percent_Identity=31.1320754716981, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI45446740, Length=198, Percent_Identity=27.7777777777778, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI47078218, Length=198, Percent_Identity=27.7777777777778, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI153792144, Length=201, Percent_Identity=28.3582089552239, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI27436953, Length=193, Percent_Identity=30.0518134715026, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI105990541, Length=190, Percent_Identity=27.3684210526316, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI31657092, Length=204, Percent_Identity=27.4509803921569, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI21536376, Length=209, Percent_Identity=27.7511961722488, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI6005701, Length=200, Percent_Identity=27, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI27262624, Length=190, Percent_Identity=25.7894736842105, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI27262626, Length=190, Percent_Identity=25.7894736842105, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI27477115, Length=195, Percent_Identity=26.6666666666667, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI116734710, Length=188, Percent_Identity=28.7234042553192, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI150417984, Length=207, Percent_Identity=26.0869565217391, Blast_Score=81, Evalue=9e-16,
Organism=Escherichia coli, GI1788761, Length=231, Percent_Identity=29.004329004329, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081782, Length=202, Percent_Identity=27.7227722772277, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788165, Length=201, Percent_Identity=28.8557213930348, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789593, Length=189, Percent_Identity=27.5132275132275, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1787029, Length=221, Percent_Identity=27.1493212669683, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787792, Length=209, Percent_Identity=30.1435406698565, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI87081709, Length=202, Percent_Identity=27.2277227722772, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1787164, Length=204, Percent_Identity=29.9019607843137, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790739, Length=244, Percent_Identity=25, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI48994943, Length=247, Percent_Identity=29.1497975708502, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786319, Length=244, Percent_Identity=26.6393442622951, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788225, Length=228, Percent_Identity=28.5087719298246, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87081791, Length=206, Percent_Identity=26.2135922330097, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787089, Length=225, Percent_Identity=26.6666666666667, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789751, Length=191, Percent_Identity=29.3193717277487, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786253, Length=193, Percent_Identity=30.0518134715026, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789672, Length=241, Percent_Identity=24.896265560166, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787370, Length=223, Percent_Identity=28.2511210762332, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1787712, Length=213, Percent_Identity=26.7605633802817, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1790467, Length=204, Percent_Identity=26.9607843137255, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI48995001, Length=209, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786398, Length=201, Percent_Identity=25.8706467661692, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790544, Length=241, Percent_Identity=27.3858921161826, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789032, Length=212, Percent_Identity=25.9433962264151, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787500, Length=199, Percent_Identity=27.1356783919598, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787105, Length=257, Percent_Identity=26.0700389105058, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789586, Length=223, Percent_Identity=27.3542600896861, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786345, Length=212, Percent_Identity=26.4150943396226, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787041, Length=203, Percent_Identity=25.1231527093596, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790525, Length=217, Percent_Identity=24.4239631336406, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87082268, Length=202, Percent_Identity=30.1980198019802, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1786872, Length=226, Percent_Identity=26.1061946902655, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1786803, Length=213, Percent_Identity=26.7605633802817, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI2367384, Length=203, Percent_Identity=28.0788177339901, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788540, Length=220, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789991, Length=214, Percent_Identity=26.6355140186916, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI87081834, Length=217, Percent_Identity=26.2672811059908, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI87082267, Length=219, Percent_Identity=25.1141552511416, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1790190, Length=224, Percent_Identity=25.8928571428571, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788450, Length=183, Percent_Identity=26.2295081967213, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI48994997, Length=221, Percent_Identity=24.8868778280543, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787182, Length=227, Percent_Identity=22.9074889867841, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1786703, Length=224, Percent_Identity=24.5535714285714, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17510237, Length=193, Percent_Identity=27.979274611399, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI115533608, Length=206, Percent_Identity=26.2135922330097, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71983510, Length=211, Percent_Identity=28.436018957346, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71983516, Length=211, Percent_Identity=28.436018957346, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71983523, Length=211, Percent_Identity=28.436018957346, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17559834, Length=195, Percent_Identity=24.1025641025641, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17565586, Length=182, Percent_Identity=22.5274725274725, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI212646699, Length=220, Percent_Identity=25.4545454545455, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6320874, Length=183, Percent_Identity=24.5901639344262, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=216, Percent_Identity=24.0740740740741, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24666092, Length=206, Percent_Identity=30.5825242718447, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI116007328, Length=207, Percent_Identity=30.9178743961353, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI28574150, Length=207, Percent_Identity=30.9178743961353, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24650855, Length=195, Percent_Identity=29.7435897435897, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI85725262, Length=195, Percent_Identity=30.2564102564103, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24650853, Length=195, Percent_Identity=29.7435897435897, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24643674, Length=206, Percent_Identity=24.2718446601942, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281362751, Length=195, Percent_Identity=29.7435897435897, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI221512771, Length=206, Percent_Identity=26.6990291262136, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI28573571, Length=187, Percent_Identity=28.8770053475936, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28573573, Length=187, Percent_Identity=28.8770053475936, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28571209, Length=207, Percent_Identity=27.0531400966184, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24582014, Length=195, Percent_Identity=25.6410256410256, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24582012, Length=195, Percent_Identity=25.6410256410256, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI116007184, Length=194, Percent_Identity=25.2577319587629, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI221500365, Length=194, Percent_Identity=25.2577319587629, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24648314, Length=209, Percent_Identity=22.9665071770335, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24581191, Length=190, Percent_Identity=30.5263157894737, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24581189, Length=190, Percent_Identity=30.5263157894737, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24581193, Length=190, Percent_Identity=30.5263157894737, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24581195, Length=190, Percent_Identity=30.5263157894737, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24662800, Length=197, Percent_Identity=28.4263959390863, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI85816269, Length=204, Percent_Identity=29.4117647058824, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24580553, Length=204, Percent_Identity=29.4117647058824, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI85724864, Length=204, Percent_Identity=29.4117647058824, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24580555, Length=204, Percent_Identity=29.4117647058824, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI19920532, Length=206, Percent_Identity=27.6699029126214, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24580930, Length=206, Percent_Identity=27.6699029126214, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: 3.6.3.25 [C]

Molecular weight: Translated: 31183; Mature: 31183

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVELRGIQKKYGKSLILDNIDLSIPEGEALAIIGGNGTGKSTLLKIIAGFISPTAGTIQ
CEEEECCHHHHHCCEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCC
RKEHIQIGYVPEHFPEGIRFTLEDYLYHLGHIHGLSTKYVKDKIPMLLESFHLHHARHSV
CCCCEEECCCHHHCCCCCEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VRNFSKGMKQKTGIMQALLTDVHLLILDEPLSGLDPNSQQELEHILLSLKQQGISVLFTC
HHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEE
HEKQLLENFADRIVTLANHTITENISAQKGAERVYIEAIVHETFSAIELQKQSGFIHVAH
HHHHHHHHHHHHHHHHHCCHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
NSNQNLIQLHIEKEHTNDILQFLLHKKASITLLQPNF
CCCCCEEEEEEECHHHHHHHHHHHHCCCEEEEECCCC
>Mature Secondary Structure
MLVELRGIQKKYGKSLILDNIDLSIPEGEALAIIGGNGTGKSTLLKIIAGFISPTAGTIQ
CEEEECCHHHHHCCEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCC
RKEHIQIGYVPEHFPEGIRFTLEDYLYHLGHIHGLSTKYVKDKIPMLLESFHLHHARHSV
CCCCEEECCCHHHCCCCCEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VRNFSKGMKQKTGIMQALLTDVHLLILDEPLSGLDPNSQQELEHILLSLKQQGISVLFTC
HHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEE
HEKQLLENFADRIVTLANHTITENISAQKGAERVYIEAIVHETFSAIELQKQSGFIHVAH
HHHHHHHHHHHHHHHHHCCHHHCCCCHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
NSNQNLIQLHIEKEHTNDILQFLLHKKASITLLQPNF
CCCCCEEEEEEECHHHHHHHHHHHHCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]