Click here to switch to the map view.

The map label for this gene is infC [H]

Identifier: 49187466

GI number: 49187466

Start: 4381324

End: 4381911

Strand: Reverse

Name: infC [H]

Synonym: BAS4471

Alternate gene names: 49187466

Gene position: 4381911-4381324 (Counterclockwise)

Preceding gene: 49187467

Following gene: 49187465

Centisome position: 83.81

GC content: 38.78

Gene sequence:

>588_bases
ATGCCCGCACTTTTTTTGTCGGGTTCTATGACTACAAACTATGTTCTGAGAAAACCTTGGAGGTGGCTTACTATTAGCAA
GGATATGATGATTAACGAGCAAATTCGTGCACGTGAAGTACGTTTAGTTGGCGCAAATGGCGATCAACTTGGAATCAAGT
CTCGTAATGACGCTTTAGACTTAGCTGCAAATCTTAATCTTGATTTAGTATTAGTTGCTCCAAATGCGAAACCGCCAGTA
TGCCGCATTATGGACTACGGTAAATTCCGCTTTGAGCAACAGAAGAAAGAAAAAGAACAGCGCAAAAATCAAAAAGTAAT
TAGCATGAAAGAAGTTCGTTTAAGTCCAACAATTGATGAACACGACTTTAACACAAAACTTCGTAATGCTATCAAGTTTT
TAGAGAAAGGCGACAAGGTTAAAGCGTCAATTCGCTTTAAAGGACGTGCCATTACTCATAAAGAAATCGGTCAACGTGTT
TTAGATCGCTTCTCAGAAGCTTGTGCTGAAGTTAGTACAATCGAATCTAAGCCTAAAATGGAAGGACGCAGTATGTTCTT
AGTTTTAGCACCGAAAAACGATAAGTAA

Upstream 100 bases:

>100_bases
GTGGAACAAGTAGAAGCACCCGCTTCTCACCTGATGGACGCATTCGCAGTTTACAGGTAAATGTATTTCTTACTTAAGAT
TTTACAAGTGTGGGTGTCGT

Downstream 100 bases:

>100_bases
TAGATAGAGGAGGAAATACCTATGCCTAAACAAAAAACTCATCGCGGCGCTGCAAAGCGTTTCAAAAAGACTGGATCAGG
TAAACTGAAACGTTCTCACG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MPALFLSGSMTTNYVLRKPWRWLTISKDMMINEQIRAREVRLVGANGDQLGIKSRNDALDLAANLNLDLVLVAPNAKPPV
CRIMDYGKFRFEQQKKEKEQRKNQKVISMKEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKASIRFKGRAITHKEIGQRV
LDRFSEACAEVSTIESKPKMEGRSMFLVLAPKNDK

Sequences:

>Translated_195_residues
MPALFLSGSMTTNYVLRKPWRWLTISKDMMINEQIRAREVRLVGANGDQLGIKSRNDALDLAANLNLDLVLVAPNAKPPV
CRIMDYGKFRFEQQKKEKEQRKNQKVISMKEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKASIRFKGRAITHKEIGQRV
LDRFSEACAEVSTIESKPKMEGRSMFLVLAPKNDK
>Mature_194_residues
PALFLSGSMTTNYVLRKPWRWLTISKDMMINEQIRAREVRLVGANGDQLGIKSRNDALDLAANLNLDLVLVAPNAKPPVC
RIMDYGKFRFEQQKKEKEQRKNQKVISMKEVRLSPTIDEHDFNTKLRNAIKFLEKGDKVKASIRFKGRAITHKEIGQRVL
DRFSEACAEVSTIESKPKMEGRSMFLVLAPKNDK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=163, Percent_Identity=53.9877300613497, Blast_Score=166, Evalue=9e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 22375; Mature: 22244

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPALFLSGSMTTNYVLRKPWRWLTISKDMMINEQIRAREVRLVGANGDQLGIKSRNDALD
CCEEEECCCCCCCCEEECCEEEEEECCCHHCCCCCCEEEEEEECCCCCEECCCCCCCCEE
LAANLNLDLVLVAPNAKPPVCRIMDYGKFRFEQQKKEKEQRKNQKVISMKEVRLSPTIDE
EEECCCEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEHEEEEECCCCCC
HDFNTKLRNAIKFLEKGDKVKASIRFKGRAITHKEIGQRVLDRFSEACAEVSTIESKPKM
CCCHHHHHHHHHHHHCCCEEEEEEEECCCEECHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EGRSMFLVLAPKNDK
CCCEEEEEEECCCCC
>Mature Secondary Structure 
PALFLSGSMTTNYVLRKPWRWLTISKDMMINEQIRAREVRLVGANGDQLGIKSRNDALD
CEEEECCCCCCCCEEECCEEEEEECCCHHCCCCCCEEEEEEECCCCCEECCCCCCCCEE
LAANLNLDLVLVAPNAKPPVCRIMDYGKFRFEQQKKEKEQRKNQKVISMKEVRLSPTIDE
EEECCCEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEHEEEEECCCCCC
HDFNTKLRNAIKFLEKGDKVKASIRFKGRAITHKEIGQRVLDRFSEACAEVSTIESKPKM
CCCHHHHHHHHHHHHCCCEEEEEEEECCCEECHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EGRSMFLVLAPKNDK
CCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]