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The map label for this gene is etfA [H]

Identifier: 49187413

GI number: 49187413

Start: 4327379

End: 4328356

Strand: Reverse

Name: etfA [H]

Synonym: BAS4418

Alternate gene names: 49187413

Gene position: 4328356-4327379 (Counterclockwise)

Preceding gene: 49187414

Following gene: 49187412

Centisome position: 82.78

GC content: 41.0

Gene sequence:

>978_bases
ATGGCTCGTAAAGTATTAGTAATGGGTGAAGTTCGTGATGGATCGCTACGTAACGTTTCGTTTGAAGCGGTAGCAGCAGC
AAAAACAATTGCAGAAGGCGGTGAAGTAGTAGGTCTTCTAGTTGGAGACAGCGTTGCTTCTTTTGCAAATGAATTGATTC
ATTACGGTGCAGATCGCGTTGTGACAGTTGAAAATGATAAATTAAAATCATATACATCTGATGGCTATGCACAAGCATTT
TTAGCTGTATATGCTGAAGAAAATCCAGAAGGTATTGTATTTGGACATACAGCACTTGGGAAAGATTTATCACCAAAATT
AGCAGCGAAGCTTGAAGCTGGTCTAGTTTCTGACGTAACTGCTTTAGAAGTTGAAGGTGGAAATGTTATCTTCACTCGTC
CAATCTACTCTGGTAAAGCATTTGAGAAGAAGATTGTAACAGACGGCATTTTATTTGCGACAGTGCGTCCAAATAACATC
GCAACGCTTGAAAAAGATGAGTCTCGCAGTGGTGACGTGTCTTCTATTACAGTAGATGTGAAAGACTTGCGTACAATCAT
ACAAGATGTCGTCCGTAAGACGGCAGAAGGCGTTGACCTTTCAGAAGCGAAAGTGATTATCGCTGGCGGACGCGGTGTGA
AGAGTGAAGACGGATTTAAACCATTAAAAGAGTTAGCTGACGTACTAGGCGGCGCTGTGGGAGCATCTCGTGGTGCTTGT
GACGCTGAGTATTGCGATTATTCATTACAAATTGGTCAAACTGGTAAAGTTGTTACACCAGACCTATACATTGCGTGCGG
TATTTCTGGTGCGATTCAGCATTTAGCTGGTATGTCTAACTCAAAAATAATCGTTGCGATTAACAAAGACCCAGAAGCAA
GTATCTTCAAAGTAGCTGACTACGGTATTGTTGGCGATTTATTTGAAGTCGTACCACTTTTAACAGAAGAGTTTAAAAAG
TTAAAAGTACATTCATGA

Upstream 100 bases:

>100_bases
CGAGCTGCAAGATCAAGTAAAAGAACTTGTATCGTTGCTCCATACAGAAGCGAAAGTAATCTAATAAAATACGAAATTAT
ATATGCAGGAGGGAAAATCT

Downstream 100 bases:

>100_bases
TTTGAGTACCCTTGAGTTCCAAGTGAAGTACCCCTATATATAGAAAAAGGTGAGAGATCCCCTGTCTCTCATCTTTTTAG
TATTTAATCCGTATTTTTAT

Product: electron transfer flavoprotein subunit alpha

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MARKVLVMGEVRDGSLRNVSFEAVAAAKTIAEGGEVVGLLVGDSVASFANELIHYGADRVVTVENDKLKSYTSDGYAQAF
LAVYAEENPEGIVFGHTALGKDLSPKLAAKLEAGLVSDVTALEVEGGNVIFTRPIYSGKAFEKKIVTDGILFATVRPNNI
ATLEKDESRSGDVSSITVDVKDLRTIIQDVVRKTAEGVDLSEAKVIIAGGRGVKSEDGFKPLKELADVLGGAVGASRGAC
DAEYCDYSLQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKIIVAINKDPEASIFKVADYGIVGDLFEVVPLLTEEFKK
LKVHS

Sequences:

>Translated_325_residues
MARKVLVMGEVRDGSLRNVSFEAVAAAKTIAEGGEVVGLLVGDSVASFANELIHYGADRVVTVENDKLKSYTSDGYAQAF
LAVYAEENPEGIVFGHTALGKDLSPKLAAKLEAGLVSDVTALEVEGGNVIFTRPIYSGKAFEKKIVTDGILFATVRPNNI
ATLEKDESRSGDVSSITVDVKDLRTIIQDVVRKTAEGVDLSEAKVIIAGGRGVKSEDGFKPLKELADVLGGAVGASRGAC
DAEYCDYSLQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKIIVAINKDPEASIFKVADYGIVGDLFEVVPLLTEEFKK
LKVHS
>Mature_324_residues
ARKVLVMGEVRDGSLRNVSFEAVAAAKTIAEGGEVVGLLVGDSVASFANELIHYGADRVVTVENDKLKSYTSDGYAQAFL
AVYAEENPEGIVFGHTALGKDLSPKLAAKLEAGLVSDVTALEVEGGNVIFTRPIYSGKAFEKKIVTDGILFATVRPNNIA
TLEKDESRSGDVSSITVDVKDLRTIIQDVVRKTAEGVDLSEAKVIIAGGRGVKSEDGFKPLKELADVLGGAVGASRGACD
AEYCDYSLQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKIIVAINKDPEASIFKVADYGIVGDLFEVVPLLTEEFKKL
KVHS

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=320, Percent_Identity=41.5625, Blast_Score=208, Evalue=7e-54,
Organism=Homo sapiens, GI189181759, Length=266, Percent_Identity=44.3609022556391, Blast_Score=195, Evalue=6e-50,
Organism=Escherichia coli, GI1787990, Length=274, Percent_Identity=33.2116788321168, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1786226, Length=273, Percent_Identity=28.9377289377289, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI87082157, Length=230, Percent_Identity=27.8260869565217, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17506929, Length=313, Percent_Identity=43.1309904153355, Blast_Score=209, Evalue=2e-54,
Organism=Saccharomyces cerevisiae, GI6325261, Length=279, Percent_Identity=38.3512544802867, Blast_Score=172, Evalue=7e-44,
Organism=Drosophila melanogaster, GI17136898, Length=321, Percent_Identity=40.4984423676012, Blast_Score=202, Evalue=3e-52,
Organism=Drosophila melanogaster, GI24652801, Length=321, Percent_Identity=40.4984423676012, Blast_Score=202, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 34342; Mature: 34210

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKVLVMGEVRDGSLRNVSFEAVAAAKTIAEGGEVVGLLVGDSVASFANELIHYGADRV
CCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCEE
VTVENDKLKSYTSDGYAQAFLAVYAEENPEGIVFGHTALGKDLSPKLAAKLEAGLVSDVT
EEEECCCCCCCCCCCHHEEEEEEEECCCCCEEEEECHHCCCCCCHHHHHHHHCCHHCCCE
ALEVEGGNVIFTRPIYSGKAFEKKIVTDGILFATVRPNNIATLEKDESRSGDVSSITVDV
EEEECCCCEEEECCCCCCCHHHHHHCCCCEEEEEECCCCEEEEECCCCCCCCCEEEEEEH
KDLRTIIQDVVRKTAEGVDLSEAKVIIAGGRGVKSEDGFKPLKELADVLGGAVGASRGAC
HHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
DAEYCDYSLQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKIIVAINKDPEASIFKVAD
CHHHCCEEEEECCCCCEECCCEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEC
YGIVGDLFEVVPLLTEEFKKLKVHS
CCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ARKVLVMGEVRDGSLRNVSFEAVAAAKTIAEGGEVVGLLVGDSVASFANELIHYGADRV
CCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCEE
VTVENDKLKSYTSDGYAQAFLAVYAEENPEGIVFGHTALGKDLSPKLAAKLEAGLVSDVT
EEEECCCCCCCCCCCHHEEEEEEEECCCCCEEEEECHHCCCCCCHHHHHHHHCCHHCCCE
ALEVEGGNVIFTRPIYSGKAFEKKIVTDGILFATVRPNNIATLEKDESRSGDVSSITVDV
EEEECCCCEEEECCCCCCCHHHHHHCCCCEEEEEECCCCEEEEECCCCCCCCCEEEEEEH
KDLRTIIQDVVRKTAEGVDLSEAKVIIAGGRGVKSEDGFKPLKELADVLGGAVGASRGAC
HHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
DAEYCDYSLQIGQTGKVVTPDLYIACGISGAIQHLAGMSNSKIIVAINKDPEASIFKVAD
CHHHCCEEEEECCCCCEECCCEEEEECCHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEC
YGIVGDLFEVVPLLTEEFKKLKVHS
CCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]