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The map label for this gene is dtd

Identifier: 49187296

GI number: 49187296

Start: 4211855

End: 4212295

Strand: Reverse

Name: dtd

Synonym: BAS4301

Alternate gene names: 49187296

Gene position: 4212295-4211855 (Counterclockwise)

Preceding gene: 49187297

Following gene: 49187295

Centisome position: 80.56

GC content: 38.78

Gene sequence:

>441_bases
ATGAGAGTTGTTTTACAACGATCAAAAGAAGCGTCTGTCACAGTAGACGGTGAGATCGTAGGACAAATTCCGTTCGGTTT
AACATTACTAGTTGGCATTACGCATGAAGATACAGAAAAAGATGCAACTTACATTGCAGAAAAAATTGCGAACTTACGTA
TTTTTGAAGATGAGAGCGGAAAGATGAACCATTCTGTACTCGATGTAGAAGGACAAGTTCTATCCATCTCGCAATTCACA
TTATACGGAGATTGCCGCAAGGGAAGACGTCCAAACTTTATGGATGCTGCCAAACCTGACTATGCAGAGCATTTATATGA
TTTCTTTAATGAAGAAGTTCGTAAGCAAGGATTGCATGTAGAAACAGGGAAGTTCGGAGCAATGATGGATGTTTCTTTAA
TCAATGATGGTCCGGTTACCTTAATTGTGGAAAGTAAATAA

Upstream 100 bases:

>100_bases
GTAACTTACAGCACTTGAAAAAAGTAGTAGAACGCATTAAACGTGTTCCAGAAATTTATGCAGTACGACGCATGATGCAT
TAATAGGGAGTGTAGAAAAG

Downstream 100 bases:

>100_bases
TGTTGCAAGAAGAGAGGATGATATCATCCTCTCTTTTTTATACATTGTTGTATGTTTTGTTCATTTATCCCGCTATTTGG
ATTCTTATTTTTAGGATTAA

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MRVVLQRSKEASVTVDGEIVGQIPFGLTLLVGITHEDTEKDATYIAEKIANLRIFEDESGKMNHSVLDVEGQVLSISQFT
LYGDCRKGRRPNFMDAAKPDYAEHLYDFFNEEVRKQGLHVETGKFGAMMDVSLINDGPVTLIVESK

Sequences:

>Translated_146_residues
MRVVLQRSKEASVTVDGEIVGQIPFGLTLLVGITHEDTEKDATYIAEKIANLRIFEDESGKMNHSVLDVEGQVLSISQFT
LYGDCRKGRRPNFMDAAKPDYAEHLYDFFNEEVRKQGLHVETGKFGAMMDVSLINDGPVTLIVESK
>Mature_146_residues
MRVVLQRSKEASVTVDGEIVGQIPFGLTLLVGITHEDTEKDATYIAEKIANLRIFEDESGKMNHSVLDVEGQVLSISQFT
LYGDCRKGRRPNFMDAAKPDYAEHLYDFFNEEVRKQGLHVETGKFGAMMDVSLINDGPVTLIVESK

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=149, Percent_Identity=46.3087248322148, Blast_Score=119, Evalue=9e-28,
Organism=Escherichia coli, GI1790320, Length=144, Percent_Identity=47.2222222222222, Blast_Score=144, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI115533292, Length=149, Percent_Identity=46.9798657718121, Blast_Score=125, Evalue=8e-30,
Organism=Saccharomyces cerevisiae, GI6319982, Length=148, Percent_Identity=41.2162162162162, Blast_Score=115, Evalue=2e-27,
Organism=Drosophila melanogaster, GI281361569, Length=147, Percent_Identity=44.8979591836735, Blast_Score=116, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_BACAA (C3P993)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002868692.1
- ProteinModelPortal:   C3P993
- SMR:   C3P993
- EnsemblBacteria:   EBBACT00000130323
- GeneID:   7848934
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_4653
- GeneTree:   EBGT00050000002392
- ProtClustDB:   PRK05273
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16323; Mature: 16323

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVVLQRSKEASVTVDGEIVGQIPFGLTLLVGITHEDTEKDATYIAEKIANLRIFEDESG
CCEEEECCCCCEEEECCEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHCEEEEECCCC
KMNHSVLDVEGQVLSISQFTLYGDCRKGRRPNFMDAAKPDYAEHLYDFFNEEVRKQGLHV
CCCCEEEECCCCEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
ETGKFGAMMDVSLINDGPVTLIVESK
ECCCCCCEEEEEEECCCCEEEEEECC
>Mature Secondary Structure
MRVVLQRSKEASVTVDGEIVGQIPFGLTLLVGITHEDTEKDATYIAEKIANLRIFEDESG
CCEEEECCCCCEEEECCEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHCEEEEECCCC
KMNHSVLDVEGQVLSISQFTLYGDCRKGRRPNFMDAAKPDYAEHLYDFFNEEVRKQGLHV
CCCCEEEECCCCEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEE
ETGKFGAMMDVSLINDGPVTLIVESK
ECCCCCCEEEEEEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA