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The map label for this gene is aroK

Identifier: 49187134

GI number: 49187134

Start: 4057062

End: 4057559

Strand: Reverse

Name: aroK

Synonym: BAS4137

Alternate gene names: 49187134

Gene position: 4057559-4057062 (Counterclockwise)

Preceding gene: 49187135

Following gene: 49187133

Centisome position: 77.6

GC content: 35.14

Gene sequence:

>498_bases
ATGAAATCTATATACATAACCGGTTATATGGGAGCTGGGAAAACAACAATTGGAAAAGCATTAAGTAAAGAACTTCATAT
GGATGTTGTAGATACAGATCAAAAAATTGAAGAGAAGCAGGGAAAAGTAATTCGTGATATTTTTGCCGAAGAAGGTGAAA
TGGCTTTTCGGGAATATGAAAGTGAAATGTTATGTTCACTACCTGTTGATAATGTAATCATTACAACTGGCGGCGGAATC
GTTGAGCGAGAGGAAAACCGAAAATGGATGAAGGAAAATGGAACTGTCGTGTATTTATATTGTGATCCACATGTAATTGC
AGAAAGGCTTCGTGAAGATACGACACGTCCACTATTTCAGAAGAAAGATATAGATGCATTTGTAACGAAATTCGAATCGC
GCCGAGCTTATTATGAAGAGGCTCATATTCATATCGATACGACGAATAAGTCTGTAAAGCAAATTATGAATGAATTAAAA
GAAAAGATTAATGAATAA

Upstream 100 bases:

>100_bases
GTTCTTCAATGCATAAGGAGAACAAAACGTTTTTTTATTAAATAAAGGAGCATCTTTCGTTATAATAACAAGTAATACAT
GACGATTGAGAGGAAAGAAC

Downstream 100 bases:

>100_bases
GAAAGTGGACATACTAATCAAGTAGAGGTGATGATAATATGTCTACTAATGATTATGTTCGCTTTGTGACACAACAGTTT
GTGTCGTATATGGATGCTCC

Product: shikimate kinase

Products: NA

Alternate protein names: SK

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MKSIYITGYMGAGKTTIGKALSKELHMDVVDTDQKIEEKQGKVIRDIFAEEGEMAFREYESEMLCSLPVDNVIITTGGGI
VEREENRKWMKENGTVVYLYCDPHVIAERLREDTTRPLFQKKDIDAFVTKFESRRAYYEEAHIHIDTTNKSVKQIMNELK
EKINE

Sequences:

>Translated_165_residues
MKSIYITGYMGAGKTTIGKALSKELHMDVVDTDQKIEEKQGKVIRDIFAEEGEMAFREYESEMLCSLPVDNVIITTGGGI
VEREENRKWMKENGTVVYLYCDPHVIAERLREDTTRPLFQKKDIDAFVTKFESRRAYYEEAHIHIDTTNKSVKQIMNELK
EKINE
>Mature_165_residues
MKSIYITGYMGAGKTTIGKALSKELHMDVVDTDQKIEEKQGKVIRDIFAEEGEMAFREYESEMLCSLPVDNVIITTGGGI
VEREENRKWMKENGTVVYLYCDPHVIAERLREDTTRPLFQKKDIDAFVTKFESRRAYYEEAHIHIDTTNKSVKQIMNELK
EKINE

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family

Homologues:

Organism=Escherichia coli, GI1786587, Length=169, Percent_Identity=34.9112426035503, Blast_Score=98, Evalue=2e-22,
Organism=Escherichia coli, GI87082255, Length=165, Percent_Identity=33.3333333333333, Blast_Score=91, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6320332, Length=149, Percent_Identity=30.8724832214765, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROK_BACAA (C3P8E3)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002868526.1
- ProteinModelPortal:   C3P8E3
- SMR:   C3P8E3
- EnsemblBacteria:   EBBACT00000128461
- GeneID:   7852395
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_4475
- GeneTree:   EBGT00050000003023
- ProtClustDB:   PRK00131
- GO:   GO:0005737
- HAMAP:   MF_00109
- InterPro:   IPR000623
- PRINTS:   PR01100

Pfam domain/function: PF01202 SKI

EC number: =2.7.1.71

Molecular weight: Translated: 19131; Mature: 19131

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: BINDING 33-33 BINDING 57-57 BINDING 78-78 BINDING 116-116 BINDING 134-134

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSIYITGYMGAGKTTIGKALSKELHMDVVDTDQKIEEKQGKVIRDIFAEEGEMAFREYE
CCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SEMLCSLPVDNVIITTGGGIVEREENRKWMKENGTVVYLYCDPHVIAERLREDTTRPLFQ
HHHEEECCCCCEEEECCCCEEECHHCHHHHHCCCCEEEEEECHHHHHHHHHHHCCCCHHH
KKDIDAFVTKFESRRAYYEEAHIHIDTTNKSVKQIMNELKEKINE
HCCHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSIYITGYMGAGKTTIGKALSKELHMDVVDTDQKIEEKQGKVIRDIFAEEGEMAFREYE
CCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SEMLCSLPVDNVIITTGGGIVEREENRKWMKENGTVVYLYCDPHVIAERLREDTTRPLFQ
HHHEEECCCCCEEEECCCCEEECHHCHHHHHCCCCEEEEEECHHHHHHHHHHHCCCCHHH
KKDIDAFVTKFESRRAYYEEAHIHIDTTNKSVKQIMNELKEKINE
HCCHHHHHHHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA