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The map label for this gene is aroQ

Identifier: 49187101

GI number: 49187101

Start: 4033007

End: 4033447

Strand: Reverse

Name: aroQ

Synonym: BAS4103

Alternate gene names: 49187101

Gene position: 4033447-4033007 (Counterclockwise)

Preceding gene: 49187102

Following gene: 49187100

Centisome position: 77.14

GC content: 41.72

Gene sequence:

>441_bases
ATGAAAAAGGTACTCCTCGTAAACGGTCCTAACCTAAATCGCCTCGGTGTCAGGGAGGTAAATGTATATGGAAAGGGCAC
GCTAGCGACACTTGAAGCAGATATGAAGCAAGAAGCAGAAGCAATGGGAGTGGAGTTAGAATGTTTCCAATCGAATCATG
AAGGTGCGATTATCGATCGTATTCATGAGGCGGAAGATATATATGAAGGGATCATTTTAAATCCTGGAGCATTTACGCAT
TATAGCTATGCGATTCGAGATGCAATTGCAAGCATTTCGATTCCTGTTATTGAAGTACATATTTCTAACATTCATCAGCG
TGAGTCGTTCCGTCACGAATCTGTGACGGCAGCTGTTTGTGCGGGACAGATTGTTGGATTTGGTTTTTATGGCTATAAGT
TAGCGTTATTTGCATTAATGGAGAAATTGAGGGAGGCATAA

Upstream 100 bases:

>100_bases
AAAGCTGAGCGAGAAGGAGAAGAGAAGACAAACTATTCAAATAAGTAACTCCTATGTTAAAATGGTATATAGATCTTTAA
TATTAAGGAGTTTTAAGCAT

Downstream 100 bases:

>100_bases
AGTAATGGAGAAAATCGAAAGATTAAGAAGTGCATTTGATGAGGCTGGTATTGACGGTATTTTGTTAACAAATGAACATA
GTCGTAGATATATGGCTAAC

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MKKVLLVNGPNLNRLGVREVNVYGKGTLATLEADMKQEAEAMGVELECFQSNHEGAIIDRIHEAEDIYEGIILNPGAFTH
YSYAIRDAIASISIPVIEVHISNIHQRESFRHESVTAAVCAGQIVGFGFYGYKLALFALMEKLREA

Sequences:

>Translated_146_residues
MKKVLLVNGPNLNRLGVREVNVYGKGTLATLEADMKQEAEAMGVELECFQSNHEGAIIDRIHEAEDIYEGIILNPGAFTH
YSYAIRDAIASISIPVIEVHISNIHQRESFRHESVTAAVCAGQIVGFGFYGYKLALFALMEKLREA
>Mature_146_residues
MKKVLLVNGPNLNRLGVREVNVYGKGTLATLEADMKQEAEAMGVELECFQSNHEGAIIDRIHEAEDIYEGIILNPGAFTH
YSYAIRDAIASISIPVIEVHISNIHQRESFRHESVTAAVCAGQIVGFGFYGYKLALFALMEKLREA

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_BACAA (C3P7X7)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002868492.1
- ProteinModelPortal:   C3P7X7
- SMR:   C3P7X7
- EnsemblBacteria:   EBBACT00000129468
- GeneID:   7850102
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_4439
- GeneTree:   EBGT00050000003572
- ProtClustDB:   PRK05395
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 16165; Mature: 16165

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 23-23 ACT_SITE 100-100 BINDING 74-74 BINDING 80-80 BINDING 87-87 BINDING 111-111

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVLLVNGPNLNRLGVREVNVYGKGTLATLEADMKQEAEAMGVELECFQSNHEGAIIDR
CCEEEEEECCCCCCCCCEEEEEECCCEEEEEHHHHHHHHHHHCCEEEEECCCCCCHHHHH
IHEAEDIYEGIILNPGAFTHYSYAIRDAIASISIPVIEVHISNIHQRESFRHESVTAAVC
HHHHHHHHCCEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHHHH
AGQIVGFGFYGYKLALFALMEKLREA
HHHHHHCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKVLLVNGPNLNRLGVREVNVYGKGTLATLEADMKQEAEAMGVELECFQSNHEGAIIDR
CCEEEEEECCCCCCCCCEEEEEECCCEEEEEHHHHHHHHHHHCCEEEEECCCCCCHHHHH
IHEAEDIYEGIILNPGAFTHYSYAIRDAIASISIPVIEVHISNIHQRESFRHESVTAAVC
HHHHHHHHCCEEECCCCCHHHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHHHHHHHHH
AGQIVGFGFYGYKLALFALMEKLREA
HHHHHHCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA