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The map label for this gene is yqhT [H]

Identifier: 49187100

GI number: 49187100

Start: 4031941

End: 4033002

Strand: Reverse

Name: yqhT [H]

Synonym: BAS4102

Alternate gene names: 49187100

Gene position: 4033002-4031941 (Counterclockwise)

Preceding gene: 49187101

Following gene: 49187099

Centisome position: 77.13

GC content: 38.7

Gene sequence:

>1062_bases
ATGGAGAAAATCGAAAGATTAAGAAGTGCATTTGATGAGGCTGGTATTGACGGTATTTTGTTAACAAATGAACATAGTCG
TAGATATATGGCTAACTTCACAGGAACAGCTGGTGTTGTCCTGATTTCGAAAAAACGCGCCCAATTTATTACAGATTTCC
GTTACGTAGAGCAGGCTAGTAAACAAGCGGTTGGATACGAGATTGTACAGCATGCAGGATTAATTATCGATGAAGTTGCA
AAGCAAGTGAAAGAACTAGGAATTCAAAAGCTTGGCTTTGAGCAAGATACTCTTACATATAGTTCTTATTCAGCTCATAA
AGAAGCGATCGATGCTGAATTTATCCCAACTTCTGGGCTTGTAGAAAAGTTACGCTTGATAAAGACTGATTCAGAGATTA
AGATATTAAAGGAAGCTGCACAGATTGCAGATGCTGCCTTTGAACATATTCTATCATTCATTCGCCCGGGAGTATCTGAA
ATTGAAGTGTCAAATGAACTTGAATTTTTCATGAGAAAACAAGGAGCAACATCTTCTTCGTTTGATATTATCGTTGCTTC
AGGTCTTCGTTCGGCATTACCGCACGGCGTGGCATCTGAAAAAGTGATAGAAACAGGAGATTTCGTTACATTAGACTTCG
GCGCTTATTACAAAGGATATTGCTCTGATATTACTCGTACGATTGCAGTTGGTGAACCATCTGATAAATTGAAAGAAATT
TATAATATCGTTTTAGAAGCACAATTACGTGGTGTGAACGGTATTAAAGCTGGTTTAACTGGCCGTGAAGCGGATGCGTT
AACGCGTGATTACATAACGGAAAAAGGATACGGTGAATACTTCGGACATTCTACTGGTCATGGAATCGGTCTTGAAATCC
ATGAAGCACCAGGTTTAGCATTCCGTTCTGATACAGTACTTGAACCAGGTATGGCTGTAACAGTAGAGCCAGGTATTTAT
ATTCCAGGTATTGGCGGCGTACGTATTGAAGATGATATCATTGTGACAAGTGAAGGTAATGAAGTAATTACGAAATCACC
AAAAGAACTTATTATTTTGTAA

Upstream 100 bases:

>100_bases
ACGGCAGCTGTTTGTGCGGGACAGATTGTTGGATTTGGTTTTTATGGCTATAAGTTAGCGTTATTTGCATTAATGGAGAA
ATTGAGGGAGGCATAAAGTA

Downstream 100 bases:

>100_bases
TACACAGGAGGATTTTTTTACATGATTTCAGTAAACGATTTTCGTACAGGTTTAACAATTGCAGTGGATAATGGCCTTTG
GCAAGTACTTGATTTCCAAC

Product: proline dipeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MEKIERLRSAFDEAGIDGILLTNEHSRRYMANFTGTAGVVLISKKRAQFITDFRYVEQASKQAVGYEIVQHAGLIIDEVA
KQVKELGIQKLGFEQDTLTYSSYSAHKEAIDAEFIPTSGLVEKLRLIKTDSEIKILKEAAQIADAAFEHILSFIRPGVSE
IEVSNELEFFMRKQGATSSSFDIIVASGLRSALPHGVASEKVIETGDFVTLDFGAYYKGYCSDITRTIAVGEPSDKLKEI
YNIVLEAQLRGVNGIKAGLTGREADALTRDYITEKGYGEYFGHSTGHGIGLEIHEAPGLAFRSDTVLEPGMAVTVEPGIY
IPGIGGVRIEDDIIVTSEGNEVITKSPKELIIL

Sequences:

>Translated_353_residues
MEKIERLRSAFDEAGIDGILLTNEHSRRYMANFTGTAGVVLISKKRAQFITDFRYVEQASKQAVGYEIVQHAGLIIDEVA
KQVKELGIQKLGFEQDTLTYSSYSAHKEAIDAEFIPTSGLVEKLRLIKTDSEIKILKEAAQIADAAFEHILSFIRPGVSE
IEVSNELEFFMRKQGATSSSFDIIVASGLRSALPHGVASEKVIETGDFVTLDFGAYYKGYCSDITRTIAVGEPSDKLKEI
YNIVLEAQLRGVNGIKAGLTGREADALTRDYITEKGYGEYFGHSTGHGIGLEIHEAPGLAFRSDTVLEPGMAVTVEPGIY
IPGIGGVRIEDDIIVTSEGNEVITKSPKELIIL
>Mature_353_residues
MEKIERLRSAFDEAGIDGILLTNEHSRRYMANFTGTAGVVLISKKRAQFITDFRYVEQASKQAVGYEIVQHAGLIIDEVA
KQVKELGIQKLGFEQDTLTYSSYSAHKEAIDAEFIPTSGLVEKLRLIKTDSEIKILKEAAQIADAAFEHILSFIRPGVSE
IEVSNELEFFMRKQGATSSSFDIIVASGLRSALPHGVASEKVIETGDFVTLDFGAYYKGYCSDITRTIAVGEPSDKLKEI
YNIVLEAQLRGVNGIKAGLTGREADALTRDYITEKGYGEYFGHSTGHGIGLEIHEAPGLAFRSDTVLEPGMAVTVEPGIY
IPGIGGVRIEDDIIVTSEGNEVITKSPKELIIL

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=261, Percent_Identity=32.5670498084291, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI260593665, Length=289, Percent_Identity=27.681660899654, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI149589008, Length=289, Percent_Identity=27.681660899654, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI264681563, Length=189, Percent_Identity=33.3333333333333, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI93141226, Length=187, Percent_Identity=35.2941176470588, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI260593663, Length=287, Percent_Identity=27.5261324041812, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI264681565, Length=186, Percent_Identity=31.7204301075269, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI164420681, Length=261, Percent_Identity=21.8390804597701, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI40385867, Length=252, Percent_Identity=23.015873015873, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1788728, Length=359, Percent_Identity=41.7827298050139, Blast_Score=293, Evalue=1e-80,
Organism=Escherichia coli, GI1789275, Length=276, Percent_Identity=33.695652173913, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786364, Length=205, Percent_Identity=26.8292682926829, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1790282, Length=303, Percent_Identity=24.7524752475248, Blast_Score=72, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17508215, Length=294, Percent_Identity=28.5714285714286, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17509539, Length=250, Percent_Identity=28, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI71989583, Length=263, Percent_Identity=24.3346007604563, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71996291, Length=277, Percent_Identity=21.6606498194946, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6321118, Length=346, Percent_Identity=26.878612716763, Blast_Score=105, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6320922, Length=244, Percent_Identity=27.0491803278689, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6322999, Length=242, Percent_Identity=29.7520661157025, Blast_Score=76, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6323273, Length=230, Percent_Identity=26.0869565217391, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19920384, Length=277, Percent_Identity=29.9638989169675, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21357079, Length=293, Percent_Identity=30.7167235494881, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21355531, Length=187, Percent_Identity=22.4598930481283, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI17137632, Length=183, Percent_Identity=32.7868852459016, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 38614; Mature: 38614

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKIERLRSAFDEAGIDGILLTNEHSRRYMANFTGTAGVVLISKKRAQFITDFRYVEQAS
CCHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHH
KQAVGYEIVQHAGLIIDEVAKQVKELGIQKLGFEQDTLTYSSYSAHKEAIDAEFIPTSGL
HHHHHHHHHHHCCHHHHHHHHHHHHCCHHHCCCCCCCEEECCHHHHHHHCCCCCCCCHHH
VEKLRLIKTDSEIKILKEAAQIADAAFEHILSFIRPGVSEIEVSNELEFFMRKQGATSSS
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEHHHHHHHHHHHCCCCCCC
FDIIVASGLRSALPHGVASEKVIETGDFVTLDFGAYYKGYCSDITRTIAVGEPSDKLKEI
CEEEEECCHHHHCCCCCCCCCEEECCCEEEEECCCHHHHHHHHHHHEEECCCCHHHHHHH
YNIVLEAQLRGVNGIKAGLTGREADALTRDYITEKGYGEYFGHSTGHGIGLEIHEAPGLA
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHCCCCCCCCCEEEEECCCCCE
FRSDTVLEPGMAVTVEPGIYIPGIGGVRIEDDIIVTSEGNEVITKSPKELIIL
ECCCCCCCCCCEEEECCCEEECCCCCEEEECCEEEECCCCEEECCCCCCEEEC
>Mature Secondary Structure
MEKIERLRSAFDEAGIDGILLTNEHSRRYMANFTGTAGVVLISKKRAQFITDFRYVEQAS
CCHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCEEEEEECHHHHHHHHHHHHHHHH
KQAVGYEIVQHAGLIIDEVAKQVKELGIQKLGFEQDTLTYSSYSAHKEAIDAEFIPTSGL
HHHHHHHHHHHCCHHHHHHHHHHHHCCHHHCCCCCCCEEECCHHHHHHHCCCCCCCCHHH
VEKLRLIKTDSEIKILKEAAQIADAAFEHILSFIRPGVSEIEVSNELEFFMRKQGATSSS
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEHHHHHHHHHHHCCCCCCC
FDIIVASGLRSALPHGVASEKVIETGDFVTLDFGAYYKGYCSDITRTIAVGEPSDKLKEI
CEEEEECCHHHHCCCCCCCCCEEECCCEEEEECCCHHHHHHHHHHHEEECCCCHHHHHHH
YNIVLEAQLRGVNGIKAGLTGREADALTRDYITEKGYGEYFGHSTGHGIGLEIHEAPGLA
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHCCCCCCCCCEEEEECCCCCE
FRSDTVLEPGMAVTVEPGIYIPGIGGVRIEDDIIVTSEGNEVITKSPKELIIL
ECCCCCCCCCCEEEECCCEEECCCCCEEEECCEEEECCCCEEECCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]