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The map label for this gene is argC

Identifier: 49187038

GI number: 49187038

Start: 3976266

End: 3977303

Strand: Reverse

Name: argC

Synonym: BAS4040

Alternate gene names: 49187038

Gene position: 3977303-3976266 (Counterclockwise)

Preceding gene: 49187040

Following gene: 49187037

Centisome position: 76.07

GC content: 38.25

Gene sequence:

>1038_bases
ATGAAGGTCGCGATTATTGGAGCAACTGGGTATGGAGGTATTGAGTTAATTCGGTTATTAGAACAACATCCATATTTTTC
GATAGCATCTCTCCATTCTTTTTCACAAGTTGGCGAGTGTATAACAAATGTATATCCGCATTTTCAAAATGTTCTTGTTC
ATACGTTACAAGAAATTGATGTGGAGGAAATAGAGAAGGAAGCAGAAATTGTATTTTTAGCAACCCCAGCAGGAGTATCA
GCAGAGTTAACTCCCAAATTATTAGCAGTAGGCTTAAAAGTAATTGACCTATCTGGAGACTTTCGTATGAAAGATCCTTT
CATATATGAACAGTGGTATAAAAGGGCAGCTGCAAAAGAAGGAGTCCTTAGGGAAGCTGTATATGGGTTAAGTGAATGGA
AAAGGTCCGAAATTCAAAAGGCAAATTTAATTGCAAACCCGGGATGTTTTGCTACAGCTGCATTATTAGCGATATTACCG
TTAGTTCGTAGCGGCATAATTGAGGAAGACTCAATTATTATTGATGCGAAATCAGGAGTATCTGGAGCAGGCAAAACGCC
AACAACGATGACTCACTTTCCTGAGTTATATGATAACTTGCGTATTTATAAAGTAAATGAGCATCAACACATTCCTGAGA
TTGAGCAAATGCTCGCGGAGTGGAATAGAGAAACGAAGCCAATCACGTTTAGTACACATTTAATACCGATATCACGTGGG
ATTATGGTTACACTGTATGCGAAAGTAAAGCGAGAAATGGAAATAGAACAACTTCAACAATTATATGAAGAAGCGTATGA
ACAATCGGCTTTTATTCGAATTCGCATGCAAGGAGAGTTTCCAAGTCCGAAAGAAGTGAGAGGCTCAAATTATTGTGATA
TGGGGATAGCTTACGATGAAAGAACAGGAAGAGTGACAATTGTTTCTGTTATAGACAATATGATGAAAGGTGCGGCTGGT
CAAGCGATTCAAAATGCAAATATAGTAGCGGGACTAGAAGAAACGACAGGTTTACAACATATGCCGCTTTATCTATAA

Upstream 100 bases:

>100_bases
GTTTTTTAAGTTTGTAAAATTTATAAATATTTAATTGACTCTATAAATATACAATATTATAATCATACTTAATTTAAAGA
ATCAATATGAGGAGGAGCAT

Downstream 100 bases:

>100_bases
GGGGGGACATGATGATTAAAGTAGCGTCTATTACAAAAGTAGAAGATGGTTCGATTGTAACGCCAAAAGGTTTCTCGGCC
ATTGGCACTGCAATTGGTCT

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MKVAIIGATGYGGIELIRLLEQHPYFSIASLHSFSQVGECITNVYPHFQNVLVHTLQEIDVEEIEKEAEIVFLATPAGVS
AELTPKLLAVGLKVIDLSGDFRMKDPFIYEQWYKRAAAKEGVLREAVYGLSEWKRSEIQKANLIANPGCFATAALLAILP
LVRSGIIEEDSIIIDAKSGVSGAGKTPTTMTHFPELYDNLRIYKVNEHQHIPEIEQMLAEWNRETKPITFSTHLIPISRG
IMVTLYAKVKREMEIEQLQQLYEEAYEQSAFIRIRMQGEFPSPKEVRGSNYCDMGIAYDERTGRVTIVSVIDNMMKGAAG
QAIQNANIVAGLEETTGLQHMPLYL

Sequences:

>Translated_345_residues
MKVAIIGATGYGGIELIRLLEQHPYFSIASLHSFSQVGECITNVYPHFQNVLVHTLQEIDVEEIEKEAEIVFLATPAGVS
AELTPKLLAVGLKVIDLSGDFRMKDPFIYEQWYKRAAAKEGVLREAVYGLSEWKRSEIQKANLIANPGCFATAALLAILP
LVRSGIIEEDSIIIDAKSGVSGAGKTPTTMTHFPELYDNLRIYKVNEHQHIPEIEQMLAEWNRETKPITFSTHLIPISRG
IMVTLYAKVKREMEIEQLQQLYEEAYEQSAFIRIRMQGEFPSPKEVRGSNYCDMGIAYDERTGRVTIVSVIDNMMKGAAG
QAIQNANIVAGLEETTGLQHMPLYL
>Mature_345_residues
MKVAIIGATGYGGIELIRLLEQHPYFSIASLHSFSQVGECITNVYPHFQNVLVHTLQEIDVEEIEKEAEIVFLATPAGVS
AELTPKLLAVGLKVIDLSGDFRMKDPFIYEQWYKRAAAKEGVLREAVYGLSEWKRSEIQKANLIANPGCFATAALLAILP
LVRSGIIEEDSIIIDAKSGVSGAGKTPTTMTHFPELYDNLRIYKVNEHQHIPEIEQMLAEWNRETKPITFSTHLIPISRG
IMVTLYAKVKREMEIEQLQQLYEEAYEQSAFIRIRMQGEFPSPKEVRGSNYCDMGIAYDERTGRVTIVSVIDNMMKGAAG
QAIQNANIVAGLEETTGLQHMPLYL

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1790396, Length=343, Percent_Identity=36.1516034985423, Blast_Score=203, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6320913, Length=346, Percent_Identity=28.9017341040462, Blast_Score=116, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGC_BACAA (C3P7R8)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002868433.1
- ProteinModelPortal:   C3P7R8
- SMR:   C3P7R8
- EnsemblBacteria:   EBBACT00000126153
- GeneID:   7849294
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_4376
- GeneTree:   EBGT00050000002599
- ProtClustDB:   PRK00436
- GO:   GO:0005737
- HAMAP:   MF_00150
- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- SMART:   SM00859
- TIGRFAMs:   TIGR01850

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.38

Molecular weight: Translated: 38604; Mature: 38604

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS01224 ARGC

Important sites: ACT_SITE 149-149

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAIIGATGYGGIELIRLLEQHPYFSIASLHSFSQVGECITNVYPHFQNVLVHTLQEID
CEEEEEECCCCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VEEIEKEAEIVFLATPAGVSAELTPKLLAVGLKVIDLSGDFRMKDPFIYEQWYKRAAAKE
HHHHCCCCCEEEEECCCCCCCCCCHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHH
GVLREAVYGLSEWKRSEIQKANLIANPGCFATAALLAILPLVRSGIIEEDSIIIDAKSGV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCC
SGAGKTPTTMTHFPELYDNLRIYKVNEHQHIPEIEQMLAEWNRETKPITFSTHLIPISRG
CCCCCCCCHHHHCHHHHCCEEEEEECCCCCCCHHHHHHHHHCCCCCCEEEEEEEEEECCC
IMVTLYAKVKREMEIEQLQQLYEEAYEQSAFIRIRMQGEFPSPKEVRGSNYCDMGIAYDE
EEEEHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHCCCCCCCCCCCEEEC
RTGRVTIVSVIDNMMKGAAGQAIQNANIVAGLEETTGLQHMPLYL
CCCCEEEHHHHHHHHHCCCCCHHCCCCEEEECHHHCCCCCCCCCC
>Mature Secondary Structure
MKVAIIGATGYGGIELIRLLEQHPYFSIASLHSFSQVGECITNVYPHFQNVLVHTLQEID
CEEEEEECCCCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VEEIEKEAEIVFLATPAGVSAELTPKLLAVGLKVIDLSGDFRMKDPFIYEQWYKRAAAKE
HHHHCCCCCEEEEECCCCCCCCCCHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHH
GVLREAVYGLSEWKRSEIQKANLIANPGCFATAALLAILPLVRSGIIEEDSIIIDAKSGV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCC
SGAGKTPTTMTHFPELYDNLRIYKVNEHQHIPEIEQMLAEWNRETKPITFSTHLIPISRG
CCCCCCCCHHHHCHHHHCCEEEEEECCCCCCCHHHHHHHHHCCCCCCEEEEEEEEEECCC
IMVTLYAKVKREMEIEQLQQLYEEAYEQSAFIRIRMQGEFPSPKEVRGSNYCDMGIAYDE
EEEEHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHCCCCCCCCCCCEEEC
RTGRVTIVSVIDNMMKGAAGQAIQNANIVAGLEETTGLQHMPLYL
CCCCEEEHHHHHHHHHCCCCCHHCCCCEEEECHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA