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The map label for this gene is argJ [H]

Identifier: 49187037

GI number: 49187037

Start: 3975031

End: 3976257

Strand: Reverse

Name: argJ [H]

Synonym: BAS4039

Alternate gene names: 49187037

Gene position: 3976257-3975031 (Counterclockwise)

Preceding gene: 49187038

Following gene: 49187036

Centisome position: 76.05

GC content: 37.82

Gene sequence:

>1227_bases
ATGATGATTAAAGTAGCGTCTATTACAAAAGTAGAAGATGGTTCGATTGTAACGCCAAAAGGTTTCTCGGCCATTGGCAC
TGCAATTGGTCTGAAAAAGGGGAAAAAGGATTTAGGGGCAATCGTTTGTGATGTACCGGCATCATGTGCTGCTGTTTATA
CAACAAATCAAATACAAGCAGCCCCGTTGCAAGTGACGAAGGATAGTATAACGACTGAGGGGAAACTACAAGCTATTATC
GTTAATAGTGGAAATGCAAATGCTTGTACAGGAATGAAAGGGTTGCAAGATGCTTACGAGATGCGTGCATTAGGGGCGGA
ACATTTTGGATTGAAAGAAAAGTATGTTGCAGTAGCTTCAACAGGTGTAATTGGTGTTCCGCTGCCGATGGATATAATCC
GAAAGGGAATTGTAACTCTTATACCGGCGAAGGAAGAAAATGGAGCTCATTCTTTTTCTGAAGCAATTTTAACGACGGAT
CTTATAACGAAAGAAACTTGCTATGAAATGATTATTGATGGGAAGAAAGTGATGATTGCTGGTGTTGCGAAAGGTTCAGG
GATGATTCATCCAAATATGGCAACGATGCTAAGTTTTATTACGACAGACGCTCGTATAGAGCATGACGTATTGCAAACAG
CATTATCACAAATAACGAATCATACATTTAATCAAATTACAGTAGATGGAGATACTTCTACGAATGATATGGTCATCGCT
ATGGCAAGTGGATTATCAGAAACGAAACCAATCGATATGGAACATGCAGATTGGGAAACTTTCGTATTTGCTTTACAGAA
GGTATGTGAAGATTTAGCCAAAAAAATTGCACAAGATGGTGAAGGTGCTACGAAGTTAATAGAAGTAAATGTGCTAGGAG
TTCAAACAAATGAAGAGGCAAAGAAAATCGCAAAGCAAATAGTCGGTTCAAGTCTTGTGAAAACAGCAATACATGGTGAA
GACCCAAATTGGGGGCGAATTATTAGCAGTATTGGACAAAGTGAAGTAGCAATTAATCCGAATACAATTGACATTACTCT
TCAATCTATATCGGTATTAAAAAATAGTGAGCCTCAAACATTTTCTGAAGAAGAAATGAAAGAGAGATTACAAGAAGATG
AAATAGTCATTAATGTGTATTTACATTTAGGTAAAGAGACAGGATCAGCTTGGGGCTGTGACTTAAGCTATGAATATGTG
AAAATAAACGCTTGTTATCGTACATAA

Upstream 100 bases:

>100_bases
AAGGTGCGGCTGGTCAAGCGATTCAAAATGCAAATATAGTAGCGGGACTAGAAGAAACGACAGGTTTACAACATATGCCG
CTTTATCTATAAGGGGGGAC

Downstream 100 bases:

>100_bases
GGAGAGGGAAGATGAACGATTATATTGTAGTGAAATGCGGCGGTAGTATGTTAGAGCAATTAAATGACGTGTTTTTTGAT
TGTATAAAGAAATTGCAACA

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS [H]

Number of amino acids: Translated: 408; Mature: 408

Protein sequence:

>408_residues
MMIKVASITKVEDGSIVTPKGFSAIGTAIGLKKGKKDLGAIVCDVPASCAAVYTTNQIQAAPLQVTKDSITTEGKLQAII
VNSGNANACTGMKGLQDAYEMRALGAEHFGLKEKYVAVASTGVIGVPLPMDIIRKGIVTLIPAKEENGAHSFSEAILTTD
LITKETCYEMIIDGKKVMIAGVAKGSGMIHPNMATMLSFITTDARIEHDVLQTALSQITNHTFNQITVDGDTSTNDMVIA
MASGLSETKPIDMEHADWETFVFALQKVCEDLAKKIAQDGEGATKLIEVNVLGVQTNEEAKKIAKQIVGSSLVKTAIHGE
DPNWGRIISSIGQSEVAINPNTIDITLQSISVLKNSEPQTFSEEEMKERLQEDEIVINVYLHLGKETGSAWGCDLSYEYV
KINACYRT

Sequences:

>Translated_408_residues
MMIKVASITKVEDGSIVTPKGFSAIGTAIGLKKGKKDLGAIVCDVPASCAAVYTTNQIQAAPLQVTKDSITTEGKLQAII
VNSGNANACTGMKGLQDAYEMRALGAEHFGLKEKYVAVASTGVIGVPLPMDIIRKGIVTLIPAKEENGAHSFSEAILTTD
LITKETCYEMIIDGKKVMIAGVAKGSGMIHPNMATMLSFITTDARIEHDVLQTALSQITNHTFNQITVDGDTSTNDMVIA
MASGLSETKPIDMEHADWETFVFALQKVCEDLAKKIAQDGEGATKLIEVNVLGVQTNEEAKKIAKQIVGSSLVKTAIHGE
DPNWGRIISSIGQSEVAINPNTIDITLQSISVLKNSEPQTFSEEEMKERLQEDEIVINVYLHLGKETGSAWGCDLSYEYV
KINACYRT
>Mature_408_residues
MMIKVASITKVEDGSIVTPKGFSAIGTAIGLKKGKKDLGAIVCDVPASCAAVYTTNQIQAAPLQVTKDSITTEGKLQAII
VNSGNANACTGMKGLQDAYEMRALGAEHFGLKEKYVAVASTGVIGVPLPMDIIRKGIVTLIPAKEENGAHSFSEAILTTD
LITKETCYEMIIDGKKVMIAGVAKGSGMIHPNMATMLSFITTDARIEHDVLQTALSQITNHTFNQITVDGDTSTNDMVIA
MASGLSETKPIDMEHADWETFVFALQKVCEDLAKKIAQDGEGATKLIEVNVLGVQTNEEAKKIAKQIVGSSLVKTAIHGE
DPNWGRIISSIGQSEVAINPNTIDITLQSISVLKNSEPQTFSEEEMKERLQEDEIVINVYLHLGKETGSAWGCDLSYEYV
KINACYRT

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate [H]

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=414, Percent_Identity=39.1304347826087, Blast_Score=247, Evalue=3e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002813
- InterPro:   IPR016117 [H]

Pfam domain/function: PF01960 ArgJ [H]

EC number: =2.3.1.35; =2.3.1.1 [H]

Molecular weight: Translated: 43872; Mature: 43872

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIKVASITKVEDGSIVTPKGFSAIGTAIGLKKGKKDLGAIVCDVPASCAAVYTTNQIQA
CEEEEEEEEEECCCCEECCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEECCCEEE
APLQVTKDSITTEGKLQAIIVNSGNANACTGMKGLQDAYEMRALGAEHFGLKEKYVAVAS
CCEEEECCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCHHHCCCCHHEEEEEE
TGVIGVPLPMDIIRKGIVTLIPAKEENGAHSFSEAILTTDLITKETCYEMIIDGKKVMIA
CCEEECCCCHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
GVAKGSGMIHPNMATMLSFITTDARIEHDVLQTALSQITNHTFNQITVDGDTSTNDMVIA
EEECCCCEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEE
MASGLSETKPIDMEHADWETFVFALQKVCEDLAKKIAQDGEGATKLIEVNVLGVQTNEEA
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCHHH
KKIAKQIVGSSLVKTAIHGEDPNWGRIISSIGQSEVAINPNTIDITLQSISVLKNSEPQT
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEECCCEEEEEEEEHHHHCCCCCCC
FSEEEMKERLQEDEIVINVYLHLGKETGSAWGCDLSYEYVKINACYRT
CCHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCEEEEEEEEEEECC
>Mature Secondary Structure
MMIKVASITKVEDGSIVTPKGFSAIGTAIGLKKGKKDLGAIVCDVPASCAAVYTTNQIQA
CEEEEEEEEEECCCCEECCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEECCCEEE
APLQVTKDSITTEGKLQAIIVNSGNANACTGMKGLQDAYEMRALGAEHFGLKEKYVAVAS
CCEEEECCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCHHHCCCCHHEEEEEE
TGVIGVPLPMDIIRKGIVTLIPAKEENGAHSFSEAILTTDLITKETCYEMIIDGKKVMIA
CCEEECCCCHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
GVAKGSGMIHPNMATMLSFITTDARIEHDVLQTALSQITNHTFNQITVDGDTSTNDMVIA
EEECCCCEECCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEE
MASGLSETKPIDMEHADWETFVFALQKVCEDLAKKIAQDGEGATKLIEVNVLGVQTNEEA
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCHHH
KKIAKQIVGSSLVKTAIHGEDPNWGRIISSIGQSEVAINPNTIDITLQSISVLKNSEPQT
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCEEECCCEEEEEEEEHHHHCCCCCCC
FSEEEMKERLQEDEIVINVYLHLGKETGSAWGCDLSYEYVKINACYRT
CCHHHHHHHHCCCCEEEEEEEEECCCCCCCCCCCCEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721630 [H]