Definition Bacillus anthracis str. Sterne chromosome, complete genome.
Accession NC_005945
Length 5,228,663

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The map label for this gene is ribD [H]

Identifier: 49187016

GI number: 49187016

Start: 3954840

End: 3955952

Strand: Direct

Name: ribD [H]

Synonym: BAS4018

Alternate gene names: 49187016

Gene position: 3954840-3955952 (Clockwise)

Preceding gene: 49187014

Following gene: 49187017

Centisome position: 75.64

GC content: 39.44

Gene sequence:

>1113_bases
ATGACAGATCAAGAATATATGAGGATTGCCCTGCAATTAGCAGAAGGAACATGTGGGCAAACAAGTCCAAATCCTATGGT
TGGTGCTGTTGTTGTAAAAGACGGAAACATCGTCGGTATGGGGGCTCATTTACGTGCTGGTGAAGAACACGCAGAAGTTC
ATGCTCTTCATATGGCTGGTGACAAAGCAAAAGGAGCCACCGTGTATGTAACCCTTGAACCATGTAGCCATTTTGGAAAA
ACACCACCTTGCTGTGAATTGCTCATCAAAAAAGAAGTCAAACGGGTTGTAATTGCTACTCTTGATTGCAATCCGCTCGT
TTCTGGTAATGGAAAAAGAAAATTAGAGGAAGCTGGCATCGAAGTAACTACCGGTGTTCTGGAAGCAGAAGCAGTTTTAT
TAAATCGCTACTTTTTTCACTACATGAAAACGAAACGTCCATTTGTAACAATAAAAACAGCGATGAGCTTAGACGGAAAA
ACAGCAACTGTTACTGGTGAAAGCAAGTGGATTACAGGTGAAAAAGCACGAGCTGATGTTCACCAATACCGCCATACACA
TGATGCGATTCTCGTTGGAGTGAATACAGTTATAGCTGATAATCCGCATTTAACAACAAGAATTCCTAACGGGGGGCAAA
ATCCTATACGAGTTATTTTAGATACCCATTTACGAACGCCACCATCTTCTCATGTCATAACAGATTCTTTAGCACCGACA
TGGATTATAGTTGGTACGGATGTAAATCAAGAGAAAATAGCTTCTTATGAATCTAAAAATATAGCTATATTCCAAATGAA
AACGAAGCAGATTGAAATACAGGATGTTTTACACTTACTCGGCGAAAAACAAATTCTTTCTCTTTTCGTCGAAGGGGGGC
AAACAGTTCATGCAAGCTTCTTACAAACAAAGTATTTCAATGAAATTGTAACTTATATAAGCCCAAAATTAATTGGTGGC
AGTAAGGCCCCTACTTTATTTGGCGGAAATGGTTTTTCAACATTACAAGATGCGCTTTCCTTGGAAATTCAAGAGATGAA
ACAAATTGGTGATGATATAAAAATCGTTGCGCATGCCCGAAACGAGGTGACGAAATGTTTACAGGAATTGTAG

Upstream 100 bases:

>100_bases
CTTTCGTATTCGAACTATATTTCTAGAAATCACGTCTCCCAAACCCCAAGGATATTAAAATCCTTGGGGTTTTTTGTTTT
TTTTAGGAGAGGTGAAGAAA

Downstream 100 bases:

>100_bases
AAGAATTAGGAACGATAACAAATATGCAACAAAGCGGAGAAGCAATGAAGTTAACGATACATGCCAATAAAATTTTATCA
GATGTTCACTTAGGTGATAG

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MTDQEYMRIALQLAEGTCGQTSPNPMVGAVVVKDGNIVGMGAHLRAGEEHAEVHALHMAGDKAKGATVYVTLEPCSHFGK
TPPCCELLIKKEVKRVVIATLDCNPLVSGNGKRKLEEAGIEVTTGVLEAEAVLLNRYFFHYMKTKRPFVTIKTAMSLDGK
TATVTGESKWITGEKARADVHQYRHTHDAILVGVNTVIADNPHLTTRIPNGGQNPIRVILDTHLRTPPSSHVITDSLAPT
WIIVGTDVNQEKIASYESKNIAIFQMKTKQIEIQDVLHLLGEKQILSLFVEGGQTVHASFLQTKYFNEIVTYISPKLIGG
SKAPTLFGGNGFSTLQDALSLEIQEMKQIGDDIKIVAHARNEVTKCLQEL

Sequences:

>Translated_370_residues
MTDQEYMRIALQLAEGTCGQTSPNPMVGAVVVKDGNIVGMGAHLRAGEEHAEVHALHMAGDKAKGATVYVTLEPCSHFGK
TPPCCELLIKKEVKRVVIATLDCNPLVSGNGKRKLEEAGIEVTTGVLEAEAVLLNRYFFHYMKTKRPFVTIKTAMSLDGK
TATVTGESKWITGEKARADVHQYRHTHDAILVGVNTVIADNPHLTTRIPNGGQNPIRVILDTHLRTPPSSHVITDSLAPT
WIIVGTDVNQEKIASYESKNIAIFQMKTKQIEIQDVLHLLGEKQILSLFVEGGQTVHASFLQTKYFNEIVTYISPKLIGG
SKAPTLFGGNGFSTLQDALSLEIQEMKQIGDDIKIVAHARNEVTKCLQEL
>Mature_369_residues
TDQEYMRIALQLAEGTCGQTSPNPMVGAVVVKDGNIVGMGAHLRAGEEHAEVHALHMAGDKAKGATVYVTLEPCSHFGKT
PPCCELLIKKEVKRVVIATLDCNPLVSGNGKRKLEEAGIEVTTGVLEAEAVLLNRYFFHYMKTKRPFVTIKTAMSLDGKT
ATVTGESKWITGEKARADVHQYRHTHDAILVGVNTVIADNPHLTTRIPNGGQNPIRVILDTHLRTPPSSHVITDSLAPTW
IIVGTDVNQEKIASYESKNIAIFQMKTKQIEIQDVLHLLGEKQILSLFVEGGQTVHASFLQTKYFNEIVTYISPKLIGGS
KAPTLFGGNGFSTLQDALSLEIQEMKQIGDDIKIVAHARNEVTKCLQEL

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=365, Percent_Identity=42.4657534246575, Blast_Score=278, Evalue=6e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 40483; Mature: 40352

Theoretical pI: Translated: 7.23; Mature: 7.23

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQEYMRIALQLAEGTCGQTSPNPMVGAVVVKDGNIVGMGAHLRAGEEHAEVHALHMAG
CCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCEEEECCCCCCCCCHHEEEEEEECC
DKAKGATVYVTLEPCSHFGKTPPCCELLIKKEVKRVVIATLDCNPLVSGNGKRKLEEAGI
CCCCCCEEEEEECCHHHCCCCCHHHHHHHHHHHCEEEEEEECCCCCCCCCCCHHHHHCCC
EVTTGVLEAEAVLLNRYFFHYMKTKRPFVTIKTAMSLDGKTATVTGESKWITGEKARADV
EEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEECCCEEECCCHHHHHH
HQYRHTHDAILVGVNTVIADNPHLTTRIPNGGQNPIRVILDTHLRTPPSSHVITDSLAPT
HHHHCCCCEEEEEEEEEEECCCEEEEECCCCCCCCEEEEEECCCCCCCCCCEEECCCCCE
WIIVGTDVNQEKIASYESKNIAIFQMKTKQIEIQDVLHLLGEKQILSLFVEGGQTVHASF
EEEEECCCCHHHHHHCCCCCEEEEEEECCEEEHHHHHHHHCCHHHHHHHHCCCCEEEHHH
LQTKYFNEIVTYISPKLIGGSKAPTLFGGNGFSTLQDALSLEIQEMKQIGDDIKIVAHAR
HHHHHHHHHHHHHCCHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEEHHH
NEVTKCLQEL
HHHHHHHHHC
>Mature Secondary Structure 
TDQEYMRIALQLAEGTCGQTSPNPMVGAVVVKDGNIVGMGAHLRAGEEHAEVHALHMAG
CCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCEEEECCCCCCCCCHHEEEEEEECC
DKAKGATVYVTLEPCSHFGKTPPCCELLIKKEVKRVVIATLDCNPLVSGNGKRKLEEAGI
CCCCCCEEEEEECCHHHCCCCCHHHHHHHHHHHCEEEEEEECCCCCCCCCCCHHHHHCCC
EVTTGVLEAEAVLLNRYFFHYMKTKRPFVTIKTAMSLDGKTATVTGESKWITGEKARADV
EEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEEECCCEEECCCHHHHHH
HQYRHTHDAILVGVNTVIADNPHLTTRIPNGGQNPIRVILDTHLRTPPSSHVITDSLAPT
HHHHCCCCEEEEEEEEEEECCCEEEEECCCCCCCCEEEEEECCCCCCCCCCEEECCCCCE
WIIVGTDVNQEKIASYESKNIAIFQMKTKQIEIQDVLHLLGEKQILSLFVEGGQTVHASF
EEEEECCCCHHHHHHCCCCCEEEEEEECCEEEHHHHHHHHCCHHHHHHHHCCCCEEEHHH
LQTKYFNEIVTYISPKLIGGSKAPTLFGGNGFSTLQDALSLEIQEMKQIGDDIKIVAHAR
HHHHHHHHHHHHHCCHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCEEEEEHHH
NEVTKCLQEL
HHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 2112225; 9068650 [H]