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The map label for this gene is dapH

Identifier: 49186889

GI number: 49186889

Start: 3840493

End: 3841215

Strand: Reverse

Name: dapH

Synonym: BAS3891

Alternate gene names: 49186889

Gene position: 3841215-3840493 (Counterclockwise)

Preceding gene: 49186890

Following gene: 49186888

Centisome position: 73.46

GC content: 37.9

Gene sequence:

>723_bases
ATGAAAATGATGGACGCTAACGAAATTATTTCGTTTATTCAAAAAAGTGAAAAGAAAACTCCTGTAAAGGTATACATAAA
AGGGGATTTAAAAGAAGTAACATTCCCTGAAACAGTACAAGCATTTGTAAATAAAAAGTCTGGTGTATTATTTGGAGAAT
GGTCTGAAATTAAGACAATTCTAGATGAAAATAGCAAATACATTGTTGATTACGTTGTTGAAAATGACCGTCGTAATTCT
GCAATTCCAATGCTTGATTTAAAAGGTATTAAAGCTCGTATTGAGCCAGGTGCGATTATTCGTGACCACGTTGAAATCGG
CGACAACGCTGTTATTATGATGAATGCAACAATTAACATCGGTGCTGTAATTGGTGAAGGTTCTATGATCGACATGAACG
CGGTACTTGGTGGACGTGCAACTGTTGGTAAGAACTGTCACGTAGGTGCAGGTGCAGTACTTGCAGGCGTTATTGAGCCA
CCTTCAGCAAAACCAGTTATCGTTGAAGACGATGTTGTAATTGGTGCTAACGTAGTTGTGTTAGAGGGAGTTACAGTAGG
TAAAGGTGCAGTTGTAGCAGCAGGAGCTGTTGTAACAGAAGATGTACCTCCATATACAGTTGTTGCAGGTACTCCAGCAC
GTGTAATTAAAGAAATTGATGAGAAGACAAAAGCAAAAACTGAAATTAAACAAGAGCTTCGTCAATTAAACCCAGAGAAA
TAA

Upstream 100 bases:

>100_bases
TTATAGAAGAAATTCAAATGGAAAAATAGGATTATTATCTTGCTACTCGCTCTATCGTTTGGTAGAGTAACATTATAAAT
GGATTTAGGAGGCAACAAGA

Downstream 100 bases:

>100_bases
AAACATAAAAGCGTAAGAGCATAAACAGGCTCTTACGCTTTTTATAGATAGAGGTGCAAAAATGGCAGTAAGCAAATTCG
TTCAAATTCGTAGAGACTTA

Product: 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-acetyltransferase; THP acetyltransferase; Tetrahydropicolinate acetylase

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MKMMDANEIISFIQKSEKKTPVKVYIKGDLKEVTFPETVQAFVNKKSGVLFGEWSEIKTILDENSKYIVDYVVENDRRNS
AIPMLDLKGIKARIEPGAIIRDHVEIGDNAVIMMNATINIGAVIGEGSMIDMNAVLGGRATVGKNCHVGAGAVLAGVIEP
PSAKPVIVEDDVVIGANVVVLEGVTVGKGAVVAAGAVVTEDVPPYTVVAGTPARVIKEIDEKTKAKTEIKQELRQLNPEK

Sequences:

>Translated_240_residues
MKMMDANEIISFIQKSEKKTPVKVYIKGDLKEVTFPETVQAFVNKKSGVLFGEWSEIKTILDENSKYIVDYVVENDRRNS
AIPMLDLKGIKARIEPGAIIRDHVEIGDNAVIMMNATINIGAVIGEGSMIDMNAVLGGRATVGKNCHVGAGAVLAGVIEP
PSAKPVIVEDDVVIGANVVVLEGVTVGKGAVVAAGAVVTEDVPPYTVVAGTPARVIKEIDEKTKAKTEIKQELRQLNPEK
>Mature_240_residues
MKMMDANEIISFIQKSEKKTPVKVYIKGDLKEVTFPETVQAFVNKKSGVLFGEWSEIKTILDENSKYIVDYVVENDRRNS
AIPMLDLKGIKARIEPGAIIRDHVEIGDNAVIMMNATINIGAVIGEGSMIDMNAVLGGRATVGKNCHVGAGAVLAGVIEP
PSAKPVIVEDDVVIGANVVVLEGVTVGKGAVVAAGAVVTEDVPPYTVVAGTPARVIKEIDEKTKAKTEIKQELRQLNPEK

Specific function: Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. DapH subfamily

Homologues:

Organism=Escherichia coli, GI1786362, Length=175, Percent_Identity=32, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1786537, Length=159, Percent_Identity=32.0754716981132, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786664, Length=148, Percent_Identity=34.4594594594595, Blast_Score=61, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322243, Length=131, Percent_Identity=37.4045801526718, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPH_BACAA (C3P6Y8)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002868281.1
- ProteinModelPortal:   C3P6Y8
- SMR:   C3P6Y8
- EnsemblBacteria:   EBBACT00000130197
- GeneID:   7852835
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_4216
- GeneTree:   EBGT00070000031764
- ProtClustDB:   CLSK917225
- HAMAP:   MF_01691
- InterPro:   IPR013710
- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR019873
- InterPro:   IPR011004
- TIGRFAMs:   TIGR03532

Pfam domain/function: PF08503 DapD_N; PF00132 Hexapep; SSF51161 Trimer_LpxA_like

EC number: =2.3.1.89

Molecular weight: Translated: 25704; Mature: 25704

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMMDANEIISFIQKSEKKTPVKVYIKGDLKEVTFPETVQAFVNKKSGVLFGEWSEIKTI
CCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCEEEECHHHHHHH
LDENSKYIVDYVVENDRRNSAIPMLDLKGIKARIEPGAIIRDHVEIGDNAVIMMNATINI
HCCCCCEEEEEEEECCCCCCCCCEEECCCCEEECCCCCEEEEEEECCCCEEEEEEEEEEE
GAVIGEGSMIDMNAVLGGRATVGKNCHVGAGAVLAGVIEPPSAKPVIVEDDVVIGANVVV
EEEECCCCEEEEHEEECCCCCCCCCCCCCCCHHEEEEECCCCCCCEEEECCEEECCCEEE
LEGVTVGKGAVVAAGAVVTEDVPPYTVVAGTPARVIKEIDEKTKAKTEIKQELRQLNPEK
EECEEECCCCEEEECEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKMMDANEIISFIQKSEKKTPVKVYIKGDLKEVTFPETVQAFVNKKSGVLFGEWSEIKTI
CCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCEEEECHHHHHHH
LDENSKYIVDYVVENDRRNSAIPMLDLKGIKARIEPGAIIRDHVEIGDNAVIMMNATINI
HCCCCCEEEEEEEECCCCCCCCCEEECCCCEEECCCCCEEEEEEECCCCEEEEEEEEEEE
GAVIGEGSMIDMNAVLGGRATVGKNCHVGAGAVLAGVIEPPSAKPVIVEDDVVIGANVVV
EEEECCCCEEEEHEEECCCCCCCCCCCCCCCHHEEEEECCCCCCCEEEECCEEECCCEEE
LEGVTVGKGAVVAAGAVVTEDVPPYTVVAGTPARVIKEIDEKTKAKTEIKQELRQLNPEK
EECEEECCCCEEEECEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA