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The map label for this gene is deoC

Identifier: 49184766

GI number: 49184766

Start: 1776936

End: 1777607

Strand: Direct

Name: deoC

Synonym: BAS1754

Alternate gene names: 49184766

Gene position: 1776936-1777607 (Clockwise)

Preceding gene: 49184765

Following gene: 49184767

Centisome position: 33.98

GC content: 37.95

Gene sequence:

>672_bases
ATGAACATTGCAAAGTTAATTGACCATACAATTTTAAAAGCTAATACTACTAAAGAAGATGTTATGAAAGTAATCGAAGA
AGCAAAGGAATATAAATTCGCTTCTGTTTGTATTAATCCTACATGGGTAAAGCTAGCTGCTGAAGAATTAGCTGGACATG
ATGTAGATGTTTGTACTGTAATCGGTTTCCCATTAGGAGCAAGCACGACTGAAACAAAAGCATTTGAAACAAAAGATGCG
ATTGCAAAAGGTGCAACTGAAGTTGATATGGTAATCAACGTAGGCGCTTTAAAAGATGGCGATAACGAACTTGTTGAAAA
AGACATTTATGAAGTAGTACAAGCAGCAAAAGGAAAAGCTCTTGTAAAAGTAATCATTGAAACTTGCCTATTAACAGATG
AAGAGAAAGTACGCGCTTGTGAATTATCAGTAAAAGCTGGTGCCGATTTCGTAAAAACTTCAACTGGATTCTCAACAGGC
GGAGCAACTGCTGAAGATATCGCATTAATGCGTAAAACAGTTGGACCAAACGTTGGTGTAAAAGCATCTGGTGGTGTTCG
TACACGTGAAGATGCAGAAAAAATGGTAGCTGCTGGAGCTTCTCGCGTTGGAGCAAGTGCTAGTGTTGCAATCGTACTAA
ATGATGCAAAAGGTGCTACAGATAACTACTAA

Upstream 100 bases:

>100_bases
AATTACTTTTAAAAGAATGAACAAAATTTCAAAAGTGTATTTACATTTGTTCAACTAAGGGTTAGAATGAAGTTGTTAAA
AGATATGAGGAGTGAAGATA

Downstream 100 bases:

>100_bases
TCATTAATGAAGTCAAAAGCAATAGATACACAAAGTAAAGTGTATCTATTGCTTTAACAATTAAAAGAAATGTAAGCGGA
TACGAATGGGAGGAGACGGC

Product: deoxyribose-phosphate aldolase

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase; DERA; Deoxyriboaldolase

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MNIAKLIDHTILKANTTKEDVMKVIEEAKEYKFASVCINPTWVKLAAEELAGHDVDVCTVIGFPLGASTTETKAFETKDA
IAKGATEVDMVINVGALKDGDNELVEKDIYEVVQAAKGKALVKVIIETCLLTDEEKVRACELSVKAGADFVKTSTGFSTG
GATAEDIALMRKTVGPNVGVKASGGVRTREDAEKMVAAGASRVGASASVAIVLNDAKGATDNY

Sequences:

>Translated_223_residues
MNIAKLIDHTILKANTTKEDVMKVIEEAKEYKFASVCINPTWVKLAAEELAGHDVDVCTVIGFPLGASTTETKAFETKDA
IAKGATEVDMVINVGALKDGDNELVEKDIYEVVQAAKGKALVKVIIETCLLTDEEKVRACELSVKAGADFVKTSTGFSTG
GATAEDIALMRKTVGPNVGVKASGGVRTREDAEKMVAAGASRVGASASVAIVLNDAKGATDNY
>Mature_223_residues
MNIAKLIDHTILKANTTKEDVMKVIEEAKEYKFASVCINPTWVKLAAEELAGHDVDVCTVIGFPLGASTTETKAFETKDA
IAKGATEVDMVINVGALKDGDNELVEKDIYEVVQAAKGKALVKVIIETCLLTDEEKVRACELSVKAGADFVKTSTGFSTG
GATAEDIALMRKTVGPNVGVKASGGVRTREDAEKMVAAGASRVGASASVAIVLNDAKGATDNY

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily

Homologues:

Organism=Homo sapiens, GI116063554, Length=187, Percent_Identity=33.1550802139037, Blast_Score=76, Evalue=3e-14,
Organism=Escherichia coli, GI1790841, Length=214, Percent_Identity=39.7196261682243, Blast_Score=107, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI17533015, Length=215, Percent_Identity=30.6976744186047, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI19922098, Length=176, Percent_Identity=34.0909090909091, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOC_BACAA (C3P786)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002866299.1
- ProteinModelPortal:   C3P786
- SMR:   C3P786
- EnsemblBacteria:   EBBACT00000127305
- GeneID:   7851056
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_1960
- GeneTree:   EBGT00050000000908
- ProtClustDB:   PRK00507
- GO:   GO:0005737
- HAMAP:   MF_00114
- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- InterPro:   IPR022979
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10889
- PIRSF:   PIRSF001357
- TIGRFAMs:   TIGR00126

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.4

Molecular weight: Translated: 23411; Mature: 23411

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: ACT_SITE 152-152 ACT_SITE 181-181

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIAKLIDHTILKANTTKEDVMKVIEEAKEYKFASVCINPTWVKLAAEELAGHDVDVCTV
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCEEEEEEECCHHHHHHHHHHCCCCCCEEEE
IGFPLGASTTETKAFETKDAIAKGATEVDMVINVGALKDGDNELVEKDIYEVVQAAKGKA
ECCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCHH
LVKVIIETCLLTDEEKVRACELSVKAGADFVKTSTGFSTGGATAEDIALMRKTVGPNVGV
HHHHHHHHHHCCCHHHHHHHEEEHHCCCCHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCE
KASGGVRTREDAEKMVAAGASRVGASASVAIVLNDAKGATDNY
ECCCCCCCHHHHHHHHHHCHHHCCCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure
MNIAKLIDHTILKANTTKEDVMKVIEEAKEYKFASVCINPTWVKLAAEELAGHDVDVCTV
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCEEEEEEECCHHHHHHHHHHCCCCCCEEEE
IGFPLGASTTETKAFETKDAIAKGATEVDMVINVGALKDGDNELVEKDIYEVVQAAKGKA
ECCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCHH
LVKVIIETCLLTDEEKVRACELSVKAGADFVKTSTGFSTGGATAEDIALMRKTVGPNVGV
HHHHHHHHHHCCCHHHHHHHEEEHHCCCCHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCE
KASGGVRTREDAEKMVAAGASRVGASASVAIVLNDAKGATDNY
ECCCCCCCHHHHHHHHHHCHHHCCCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA