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The map label for this gene is recU

Identifier: 49184476

GI number: 49184476

Start: 1483679

End: 1484281

Strand: Reverse

Name: recU

Synonym: BAS1459

Alternate gene names: 49184476

Gene position: 1484281-1483679 (Counterclockwise)

Preceding gene: 49184480

Following gene: 49184475

Centisome position: 28.39

GC content: 32.84

Gene sequence:

>603_bases
ATGACCATTCGTTACCCAAATGGAAAACGGTACAATCAAGCTTCACAACCTCATAAAACACCAATTAAAAAACATACTTA
TAGTAACAGAGGTATGTCCCTTGAAGAGGAATTGAATGAAACAAATGAATATTACTTAACCCATAATATTGCATGTGTAC
ATAAAAAACCTACACCTCTTCAAATTGTAAAAGTAGATTACCCCGCTCGAAGTGCTGCAGTGGTAAAAGAGGCGTATTTT
AAACAACCTTCTACAACAGATTACAACGGTGTATATAAAGGGAAATACATCGATTTTGAAGCGAAAGAAACAAAAAATAA
AACCAGCTTTCCACTTCAAAACTTCCACCTTCATCAAATTGAACATATGAAGCAAGTAATTGCTCATAATGGAATTGCAT
TTGTTATTATTAAATTTACACTTTTTGATGAACTTTATTTATTAGATGCAAAACATATTATTACATTTTGGAATCGTCAA
AATACTGGTGGACGAAAATCGATTACGAAAGAAGAAATAGTAGAGCATGGATCTTTATTATCATGCGGTTATCACCCTCG
GATTGATTATATCCGTGTACTAGACACGGTTTATTTTTCGTGA

Upstream 100 bases:

>100_bases
TAAGTCATCACACCTTTCTTCAAAAAGGTCACATCTTTTTTCATTTTTTGTTATAATCACCTTTGTAAGTAATTCTTAGC
AAGTTGGGAGTGGACACACT

Downstream 100 bases:

>100_bases
TAGAGTCATCACTAAGGCTCTTTTTTCGACTTTTGGGGAGAGAATGAAAGGTAGGAGAAAGTATAATGTCAGATAATTAT
CGTTCTCGTACAGAACGAAA

Product: Holliday junction-specific endonuclease

Products: NA

Alternate protein names: Recombination protein U homolog

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MTIRYPNGKRYNQASQPHKTPIKKHTYSNRGMSLEEELNETNEYYLTHNIACVHKKPTPLQIVKVDYPARSAAVVKEAYF
KQPSTTDYNGVYKGKYIDFEAKETKNKTSFPLQNFHLHQIEHMKQVIAHNGIAFVIIKFTLFDELYLLDAKHIITFWNRQ
NTGGRKSITKEEIVEHGSLLSCGYHPRIDYIRVLDTVYFS

Sequences:

>Translated_200_residues
MTIRYPNGKRYNQASQPHKTPIKKHTYSNRGMSLEEELNETNEYYLTHNIACVHKKPTPLQIVKVDYPARSAAVVKEAYF
KQPSTTDYNGVYKGKYIDFEAKETKNKTSFPLQNFHLHQIEHMKQVIAHNGIAFVIIKFTLFDELYLLDAKHIITFWNRQ
NTGGRKSITKEEIVEHGSLLSCGYHPRIDYIRVLDTVYFS
>Mature_199_residues
TIRYPNGKRYNQASQPHKTPIKKHTYSNRGMSLEEELNETNEYYLTHNIACVHKKPTPLQIVKVDYPARSAAVVKEAYFK
QPSTTDYNGVYKGKYIDFEAKETKNKTSFPLQNFHLHQIEHMKQVIAHNGIAFVIIKFTLFDELYLLDAKHIITFWNRQN
TGGRKSITKEEIVEHGSLLSCGYHPRIDYIRVLDTVYFS

Specific function: Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair

COG id: COG3331

COG function: function code R; Penicillin-binding protein-related factor A, putative recombinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recU family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RECU_BACAA (C3P5S0)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002866053.1
- ProteinModelPortal:   C3P5S0
- SMR:   C3P5S0
- EnsemblBacteria:   EBBACT00000128778
- GeneID:   7851377
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_1640
- GeneTree:   EBGT00050000001230
- ProtClustDB:   PRK02234
- GO:   GO:0005737
- HAMAP:   MF_00130
- InterPro:   IPR004612
- InterPro:   IPR011335
- PIRSF:   PIRSF037785
- TIGRFAMs:   TIGR00648

Pfam domain/function: PF03838 RecU; SSF52980 Restrict_endonuc_II-like_core

EC number: NA

Molecular weight: Translated: 23343; Mature: 23212

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRYPNGKRYNQASQPHKTPIKKHTYSNRGMSLEEELNETNEYYLTHNIACVHKKPTPL
CEEECCCCCCCCCCCCCCCCCCHHCCCCCCCCCHHHHHCCCCCEEEEEEEEEEECCCCCE
QIVKVDYPARSAAVVKEAYFKQPSTTDYNGVYKGKYIDFEAKETKNKTSFPLQNFHLHQI
EEEEECCCCCHHHHHHHHHHCCCCCCCCCCEECCEEEEEECHHCCCCCCCCCCCCHHHHH
EHMKQVIAHNGIAFVIIKFTLFDELYLLDAKHIITFWNRQNTGGRKSITKEEIVEHGSLL
HHHHHHHHCCCEEEEEEEEHHHHHHHEECCCEEEEEECCCCCCCCCCCCHHHHHHCCCEE
SCGYHPRIDYIRVLDTVYFS
ECCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TIRYPNGKRYNQASQPHKTPIKKHTYSNRGMSLEEELNETNEYYLTHNIACVHKKPTPL
EEECCCCCCCCCCCCCCCCCCHHCCCCCCCCCHHHHHCCCCCEEEEEEEEEEECCCCCE
QIVKVDYPARSAAVVKEAYFKQPSTTDYNGVYKGKYIDFEAKETKNKTSFPLQNFHLHQI
EEEEECCCCCHHHHHHHHHHCCCCCCCCCCEECCEEEEEECHHCCCCCCCCCCCCHHHHH
EHMKQVIAHNGIAFVIIKFTLFDELYLLDAKHIITFWNRQNTGGRKSITKEEIVEHGSLL
HHHHHHHHCCCEEEEEEEEHHHHHHHEECCCEEEEEECCCCCCCCCCCCHHHHHHCCCEE
SCGYHPRIDYIRVLDTVYFS
ECCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA