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The map label for this gene is yclF [H]

Identifier: 49183605

GI number: 49183605

Start: 627435

End: 628793

Strand: Reverse

Name: yclF [H]

Synonym: BAS0580

Alternate gene names: 49183605

Gene position: 628793-627435 (Counterclockwise)

Preceding gene: 49183606

Following gene: 49183602

Centisome position: 12.03

GC content: 35.39

Gene sequence:

>1359_bases
ATGGATGCAGCTTTAAAATTAGACAAAGCTGGAGAGCAACAATCACCAAAAAAACATCCACCAGGATTGTACTTGTTGTT
CTTAACAGAAATGTGGGAAAGATTTAGTTATTATGGAATGCGTGGCCTTTTAGTTCTTTATTTAACAACTGCTGCCGTTA
GTGGCGGATTAGGATTTGATAAGGCATTCGCAGTGCAATTATATGGCACTTTTACAGCGGCAGTATATTTCATGCCAATT
ATAGGCGGATGGCTAACTGATCATTATATTACGAGACGTCATGCCATTACTCTCGGCGGAATTATTATGGCAATTGGTAA
CTTTGTACTATTCTCCATGAATACAAAAACAGGACTATTCCTTGGATTAGTACTATTAGTTATTGGTAATGGATTCTTCA
AACCAAATATTTCTACACTGTTAGGTGAATTGTATGAAGAAAATGATTCACGTCGTGACAGTGCATTTACTATCTTTTAT
ATGGGTATTAACGTAGGTGCTTTCTTCGCTCCACTTATTTGTGGATTTTTAGCAGAAGATTTCTTTAAAACAAGCGTTGA
TGGCGTTATGGTTATGGGATATAAATACGGATTCTTAGCAGCTTGTATCGGTATGATTATTGGACAAATTGTTTTCAACT
TATTAGCTCCTCGCTATCTTGGTACAGCAGGAACAACAGTTATTGGTAAAAAAACAAAAAATCAACCTGCAGTCGAAAAG
AAACCTTTAACAAAACAAGAAAAAAACCGCACTTGGGCAATTGTAATTTTAACTTGTTTCGTAGTATTCTTCTGGGCAGG
CTTTGAACAAGCTGGTAGTTCTTTAACACTTTATACAGATAAATTTGTTGATCGTACAATTTTTGGATGGGAAATTCCAA
CATCTTGGTTCCAATCCGTTAATCCAGCGTTCATCGTACTACTTGCACCATTCGTATCTATGCTATGGTTAAAACTTTCT
AAATCAAAGCGTGGCGATTTAAAAATACCAACAAAAATGGCATTTGGTATGATTTTACTAGGTATAGGTTACCTTGTTTT
AACATTAGCGGTTCTAAAAACTGGAAGTAGTGAAGCTGATATAACTGTTAAAGCAAACTTATTATTCATCGTTATCACTT
ATATGTTCCATACAATTGGAGAACTATTCTTATCACCAATCGGTCTATCAATGGTAAGTGCAATTGCACCTGTTAAATTA
GCATCATTACTAATGGGTGTATGGTTAGCTGGTAAACTTGCTTCCTTTACACAATCATTAGGATACCTTGAAGTATTTGC
AAGTATTGGCATTATCGTTATCGTCTTAGGACTTGTACTCCTTCTCTTCTCTAAAAAAGTTGCGAGTATGATGGAATAA

Upstream 100 bases:

>100_bases
TTTTCTTTCTATTTCCATATAATTCTATTGACTTCTAAATATTTTGTAAATTAAAATGATTACATAAATATCCGTTATAC
AGGATTAGGGGGAAACAAAA

Downstream 100 bases:

>100_bases
TACAAAAAAGACGCTTCTGATTTTAGAAGCGTCTTTTCTATTACTTCTCCTCTAAAGCGTTCACGTGAACGTGAACGCTT
TCTCCAGGATTAGATACATC

Product: proton/peptide symporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MDAALKLDKAGEQQSPKKHPPGLYLLFLTEMWERFSYYGMRGLLVLYLTTAAVSGGLGFDKAFAVQLYGTFTAAVYFMPI
IGGWLTDHYITRRHAITLGGIIMAIGNFVLFSMNTKTGLFLGLVLLVIGNGFFKPNISTLLGELYEENDSRRDSAFTIFY
MGINVGAFFAPLICGFLAEDFFKTSVDGVMVMGYKYGFLAACIGMIIGQIVFNLLAPRYLGTAGTTVIGKKTKNQPAVEK
KPLTKQEKNRTWAIVILTCFVVFFWAGFEQAGSSLTLYTDKFVDRTIFGWEIPTSWFQSVNPAFIVLLAPFVSMLWLKLS
KSKRGDLKIPTKMAFGMILLGIGYLVLTLAVLKTGSSEADITVKANLLFIVITYMFHTIGELFLSPIGLSMVSAIAPVKL
ASLLMGVWLAGKLASFTQSLGYLEVFASIGIIVIVLGLVLLLFSKKVASMME

Sequences:

>Translated_452_residues
MDAALKLDKAGEQQSPKKHPPGLYLLFLTEMWERFSYYGMRGLLVLYLTTAAVSGGLGFDKAFAVQLYGTFTAAVYFMPI
IGGWLTDHYITRRHAITLGGIIMAIGNFVLFSMNTKTGLFLGLVLLVIGNGFFKPNISTLLGELYEENDSRRDSAFTIFY
MGINVGAFFAPLICGFLAEDFFKTSVDGVMVMGYKYGFLAACIGMIIGQIVFNLLAPRYLGTAGTTVIGKKTKNQPAVEK
KPLTKQEKNRTWAIVILTCFVVFFWAGFEQAGSSLTLYTDKFVDRTIFGWEIPTSWFQSVNPAFIVLLAPFVSMLWLKLS
KSKRGDLKIPTKMAFGMILLGIGYLVLTLAVLKTGSSEADITVKANLLFIVITYMFHTIGELFLSPIGLSMVSAIAPVKL
ASLLMGVWLAGKLASFTQSLGYLEVFASIGIIVIVLGLVLLLFSKKVASMME
>Mature_452_residues
MDAALKLDKAGEQQSPKKHPPGLYLLFLTEMWERFSYYGMRGLLVLYLTTAAVSGGLGFDKAFAVQLYGTFTAAVYFMPI
IGGWLTDHYITRRHAITLGGIIMAIGNFVLFSMNTKTGLFLGLVLLVIGNGFFKPNISTLLGELYEENDSRRDSAFTIFY
MGINVGAFFAPLICGFLAEDFFKTSVDGVMVMGYKYGFLAACIGMIIGQIVFNLLAPRYLGTAGTTVIGKKTKNQPAVEK
KPLTKQEKNRTWAIVILTCFVVFFWAGFEQAGSSLTLYTDKFVDRTIFGWEIPTSWFQSVNPAFIVLLAPFVSMLWLKLS
KSKRGDLKIPTKMAFGMILLGIGYLVLTLAVLKTGSSEADITVKANLLFIVITYMFHTIGELFLSPIGLSMVSAIAPVKL
ASLLMGVWLAGKLASFTQSLGYLEVFASIGIIVIVLGLVLLLFSKKVASMME

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=375, Percent_Identity=26.1333333333333, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI226371746, Length=359, Percent_Identity=24.7910863509749, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI226371748, Length=350, Percent_Identity=24, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1786927, Length=449, Percent_Identity=30.2895322939866, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI1790572, Length=461, Percent_Identity=31.4533622559653, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1787922, Length=485, Percent_Identity=29.6907216494845, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI1789911, Length=474, Percent_Identity=29.3248945147679, Blast_Score=181, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI71987453, Length=384, Percent_Identity=23.9583333333333, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17541704, Length=386, Percent_Identity=27.2020725388601, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17569141, Length=205, Percent_Identity=30.7317073170732, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28571102, Length=391, Percent_Identity=25.3196930946292, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28571100, Length=391, Percent_Identity=25.3196930946292, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI28571098, Length=370, Percent_Identity=25.9459459459459, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24639585, Length=328, Percent_Identity=27.1341463414634, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24639583, Length=328, Percent_Identity=27.1341463414634, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24639581, Length=338, Percent_Identity=26.6272189349112, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 49686; Mature: 49686

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS50850 MFS ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAALKLDKAGEQQSPKKHPPGLYLLFLTEMWERFSYYGMRGLLVLYLTTAAVSGGLGFD
CCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KAFAVQLYGTFTAAVYFMPIIGGWLTDHYITRRHAITLGGIIMAIGNFVLFSMNTKTGLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHH
LGLVLLVIGNGFFKPNISTLLGELYEENDSRRDSAFTIFYMGINVGAFFAPLICGFLAED
HHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHH
FFKTSVDGVMVMGYKYGFLAACIGMIIGQIVFNLLAPRYLGTAGTTVIGKKTKNQPAVEK
HHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCC
KPLTKQEKNRTWAIVILTCFVVFFWAGFEQAGSSLTLYTDKFVDRTIFGWEIPTSWFQSV
CCCCHHHCCCCHHHHHHHHHHHHHHHCHHHHCCEEEEEEHHHHHHCEECCCCCHHHHHCC
NPAFIVLLAPFVSMLWLKLSKSKRGDLKIPTKMAFGMILLGIGYLVLTLAVLKTGSSEAD
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ITVKANLLFIVITYMFHTIGELFLSPIGLSMVSAIAPVKLASLLMGVWLAGKLASFTQSL
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYLEVFASIGIIVIVLGLVLLLFSKKVASMME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDAALKLDKAGEQQSPKKHPPGLYLLFLTEMWERFSYYGMRGLLVLYLTTAAVSGGLGFD
CCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
KAFAVQLYGTFTAAVYFMPIIGGWLTDHYITRRHAITLGGIIMAIGNFVLFSMNTKTGLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHH
LGLVLLVIGNGFFKPNISTLLGELYEENDSRRDSAFTIFYMGINVGAFFAPLICGFLAED
HHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHH
FFKTSVDGVMVMGYKYGFLAACIGMIIGQIVFNLLAPRYLGTAGTTVIGKKTKNQPAVEK
HHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCC
KPLTKQEKNRTWAIVILTCFVVFFWAGFEQAGSSLTLYTDKFVDRTIFGWEIPTSWFQSV
CCCCHHHCCCCHHHHHHHHHHHHHHHCHHHHCCEEEEEEHHHHHHCEECCCCCHHHHHCC
NPAFIVLLAPFVSMLWLKLSKSKRGDLKIPTKMAFGMILLGIGYLVLTLAVLKTGSSEAD
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ITVKANLLFIVITYMFHTIGELFLSPIGLSMVSAIAPVKLASLLMGVWLAGKLASFTQSL
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GYLEVFASIGIIVIVLGLVLLLFSKKVASMME
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]