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The map label for this gene is hutM [H]

Identifier: 49183494

GI number: 49183494

Start: 487906

End: 489327

Strand: Direct

Name: hutM [H]

Synonym: BAS0466

Alternate gene names: 49183494

Gene position: 487906-489327 (Clockwise)

Preceding gene: 49183493

Following gene: 49183495

Centisome position: 9.33

GC content: 37.48

Gene sequence:

>1422_bases
ATGATGAATCAAAACCAAGGATTAAAAAGAGAATTGAAGAGCAGGCACATATTTATGATTGCACTTGGAGGAGTTATTGG
TACTGGCCTTTTTTTAGGATCTGGGTATACAATTCATGAAGCTGGGCCTGGAGGAGCGATTGTAGCGTATCTTGTCGGAG
GATTTGTTATGTATTTAACGATGCTCTGTCTTGGAGAGTTAGCTGTTGCAATGCCTGACGCAGGGTCTTATCAAACGTAT
GCAACTAAGCACATTTCCCCTGCAGCGGGTTATGTAGTCGGATGGATGTCGTGGTTGAACTGGTCAGCTACGATAGGTAT
TGAACTAATTGCAGTTAGTATTTTAATGAAACGATGGTTTCCAGATGTACCGTCATGGATTTGGTGCGTAGTGTTTGCGG
TACTGCTTTTTGCTATTAATGCGTTATCTTCAAGAAGTTTTGCAGAAGTTGAATTTTGGTTTGCAAGTATTAAAGTCATT
ACAATCATTGCATTTATTATTTTGGGCGGGGCAGCAATGTTTGGTTTTCTAGATATGAAAGGAAATGAACCAGCACCAAT
GTTCTCTAGTTTTACTGATTATGGTGGATTGTTTCCAAATGGATTATCCGCTATTTTAATTACGATGATTGCTGTTAACT
TTTCCTTCCAAGGAACAGAACTAGTCGGTATTGCAGCAGGTGAGAGTGAAAATCCAGAGAAAACAATCCCGAAGGCAATT
AATAATACAGTTTGGCGTATACTCGTGTTCTTTGTATTATCTATTTTCATTCTTGCAGGATTATTCCCTTGGCAACAGGC
GGGAGTAATAGAAAGTCCATTCGTAGTTGTATTTGATAAAATTGGTATTCCTTATGCAGCCGATATTATCAATTTCGTTA
TTATTACAGCGGTTCTATCCGTTGCGAATTCAGGATTATACGCAACTTCTCGTATGCTATGGTCTATGTCTAATCAAGGA
ATGATTAGTCCGATTTTTGGTAAGTTATCTAAAAATGGTGTTCCTATTTATGCATTGATTGTAAGTACAATTGTAGGTTG
CCTTTCATTACTATCAGGTATTTATGCGGAAGATACAGTTTATTTATGGCTACTTTCTATTGCCGGGTTCGGAGCGATAT
TAGTTTGGGCATCTATTGCTCTATCTAACTTATTAGCTAGAAGGTCATATATAAAGCAGGGCGGAGATGTGAAAGACTTG
AAATTTAAAACACCACTGTATCCATTCGTACCGCTGCTTGCATTAGTATTAAATGTAACAGTAATTGTTGGTATGGCCTT
TATTCCAGAACAAAGAATGGCGTTATATTGTGGAATTCCATTTATGATTGTTTGCTTACTGTTTTACCGTGCGACAAGAA
ATAAGGCACATAAAGTAGAACATATTGAAAAGACAGATACAACAGAAGTAGACAGTTTATAA

Upstream 100 bases:

>100_bases
ATGATATGTATTTTGCACTCTTTAATAATTTATTTTACGATGAAGAATTTTTGAAACGCTTACATTTGATGGGGTTACAA
AGTGAAAAGGGGGGATTTAT

Downstream 100 bases:

>100_bases
TATTGAGTAATTTAGAGACTGTAAAATTGTAAACAGTCTCTTTTTTTGTGAAAATAAAGCTGGAAACATATTATGTATGT
AAAGGGGGATTAGCGATGAA

Product: amino acid permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MMNQNQGLKRELKSRHIFMIALGGVIGTGLFLGSGYTIHEAGPGGAIVAYLVGGFVMYLTMLCLGELAVAMPDAGSYQTY
ATKHISPAAGYVVGWMSWLNWSATIGIELIAVSILMKRWFPDVPSWIWCVVFAVLLFAINALSSRSFAEVEFWFASIKVI
TIIAFIILGGAAMFGFLDMKGNEPAPMFSSFTDYGGLFPNGLSAILITMIAVNFSFQGTELVGIAAGESENPEKTIPKAI
NNTVWRILVFFVLSIFILAGLFPWQQAGVIESPFVVVFDKIGIPYAADIINFVIITAVLSVANSGLYATSRMLWSMSNQG
MISPIFGKLSKNGVPIYALIVSTIVGCLSLLSGIYAEDTVYLWLLSIAGFGAILVWASIALSNLLARRSYIKQGGDVKDL
KFKTPLYPFVPLLALVLNVTVIVGMAFIPEQRMALYCGIPFMIVCLLFYRATRNKAHKVEHIEKTDTTEVDSL

Sequences:

>Translated_473_residues
MMNQNQGLKRELKSRHIFMIALGGVIGTGLFLGSGYTIHEAGPGGAIVAYLVGGFVMYLTMLCLGELAVAMPDAGSYQTY
ATKHISPAAGYVVGWMSWLNWSATIGIELIAVSILMKRWFPDVPSWIWCVVFAVLLFAINALSSRSFAEVEFWFASIKVI
TIIAFIILGGAAMFGFLDMKGNEPAPMFSSFTDYGGLFPNGLSAILITMIAVNFSFQGTELVGIAAGESENPEKTIPKAI
NNTVWRILVFFVLSIFILAGLFPWQQAGVIESPFVVVFDKIGIPYAADIINFVIITAVLSVANSGLYATSRMLWSMSNQG
MISPIFGKLSKNGVPIYALIVSTIVGCLSLLSGIYAEDTVYLWLLSIAGFGAILVWASIALSNLLARRSYIKQGGDVKDL
KFKTPLYPFVPLLALVLNVTVIVGMAFIPEQRMALYCGIPFMIVCLLFYRATRNKAHKVEHIEKTDTTEVDSL
>Mature_473_residues
MMNQNQGLKRELKSRHIFMIALGGVIGTGLFLGSGYTIHEAGPGGAIVAYLVGGFVMYLTMLCLGELAVAMPDAGSYQTY
ATKHISPAAGYVVGWMSWLNWSATIGIELIAVSILMKRWFPDVPSWIWCVVFAVLLFAINALSSRSFAEVEFWFASIKVI
TIIAFIILGGAAMFGFLDMKGNEPAPMFSSFTDYGGLFPNGLSAILITMIAVNFSFQGTELVGIAAGESENPEKTIPKAI
NNTVWRILVFFVLSIFILAGLFPWQQAGVIESPFVVVFDKIGIPYAADIINFVIITAVLSVANSGLYATSRMLWSMSNQG
MISPIFGKLSKNGVPIYALIVSTIVGCLSLLSGIYAEDTVYLWLLSIAGFGAILVWASIALSNLLARRSYIKQGGDVKDL
KFKTPLYPFVPLLALVLNVTVIVGMAFIPEQRMALYCGIPFMIVCLLFYRATRNKAHKVEHIEKTDTTEVDSL

Specific function: Transporter For The Intake Of S-Methylmethionine. [C]

COG id: COG0833

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081708, Length=464, Percent_Identity=51.7241379310345, Blast_Score=510, Evalue=1e-146,
Organism=Escherichia coli, GI1788480, Length=477, Percent_Identity=41.2997903563941, Blast_Score=378, Evalue=1e-106,
Organism=Escherichia coli, GI1786302, Length=466, Percent_Identity=38.8412017167382, Blast_Score=305, Evalue=3e-84,
Organism=Escherichia coli, GI48994972, Length=471, Percent_Identity=36.3057324840764, Blast_Score=298, Evalue=5e-82,
Organism=Escherichia coli, GI1786789, Length=453, Percent_Identity=36.8653421633554, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI1789017, Length=454, Percent_Identity=37.0044052863436, Blast_Score=285, Evalue=7e-78,
Organism=Escherichia coli, GI1786602, Length=460, Percent_Identity=36.5217391304348, Blast_Score=277, Evalue=9e-76,
Organism=Escherichia coli, GI87081915, Length=426, Percent_Identity=37.5586854460094, Blast_Score=275, Evalue=4e-75,
Organism=Escherichia coli, GI1790653, Length=441, Percent_Identity=36.281179138322, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI87081869, Length=257, Percent_Identity=28.0155642023346, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87082250, Length=447, Percent_Identity=24.1610738255034, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87082023, Length=224, Percent_Identity=27.6785714285714, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI2367353, Length=350, Percent_Identity=26, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=441, Percent_Identity=21.5419501133787, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17540018, Length=375, Percent_Identity=22.6666666666667, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17533459, Length=437, Percent_Identity=23.7986270022883, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17531343, Length=431, Percent_Identity=21.5777262180974, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320772, Length=440, Percent_Identity=34.5454545454545, Blast_Score=246, Evalue=8e-66,
Organism=Saccharomyces cerevisiae, GI6324061, Length=499, Percent_Identity=31.2625250501002, Blast_Score=245, Evalue=9e-66,
Organism=Saccharomyces cerevisiae, GI6324553, Length=405, Percent_Identity=34.0740740740741, Blast_Score=233, Evalue=7e-62,
Organism=Saccharomyces cerevisiae, GI6324059, Length=429, Percent_Identity=34.2657342657343, Blast_Score=223, Evalue=5e-59,
Organism=Saccharomyces cerevisiae, GI6320717, Length=419, Percent_Identity=31.0262529832936, Blast_Score=223, Evalue=7e-59,
Organism=Saccharomyces cerevisiae, GI6319824, Length=417, Percent_Identity=30.9352517985612, Blast_Score=221, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6322892, Length=409, Percent_Identity=33.0073349633252, Blast_Score=217, Evalue=3e-57,
Organism=Saccharomyces cerevisiae, GI6324990, Length=498, Percent_Identity=29.718875502008, Blast_Score=209, Evalue=6e-55,
Organism=Saccharomyces cerevisiae, GI6320251, Length=418, Percent_Identity=30.1435406698565, Blast_Score=207, Evalue=4e-54,
Organism=Saccharomyces cerevisiae, GI6319543, Length=418, Percent_Identity=30.1435406698565, Blast_Score=206, Evalue=8e-54,
Organism=Saccharomyces cerevisiae, GI6319542, Length=439, Percent_Identity=28.9293849658314, Blast_Score=199, Evalue=6e-52,
Organism=Saccharomyces cerevisiae, GI6321053, Length=423, Percent_Identity=28.6052009456265, Blast_Score=199, Evalue=7e-52,
Organism=Saccharomyces cerevisiae, GI6321629, Length=481, Percent_Identity=28.0665280665281, Blast_Score=199, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6324924, Length=473, Percent_Identity=29.8097251585624, Blast_Score=196, Evalue=7e-51,
Organism=Saccharomyces cerevisiae, GI6322967, Length=509, Percent_Identity=26.5225933202358, Blast_Score=190, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6324981, Length=484, Percent_Identity=29.3388429752066, Blast_Score=176, Evalue=6e-45,
Organism=Saccharomyces cerevisiae, GI6319608, Length=433, Percent_Identity=26.0969976905312, Blast_Score=167, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6320364, Length=490, Percent_Identity=24.0816326530612, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24667468, Length=369, Percent_Identity=22.4932249322493, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221512776, Length=435, Percent_Identity=20, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24666159, Length=435, Percent_Identity=20, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51572; Mature: 51572

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNQNQGLKRELKSRHIFMIALGGVIGTGLFLGSGYTIHEAGPGGAIVAYLVGGFVMYLT
CCCCCCCHHHHHHHCEEEEEEHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHH
MLCLGELAVAMPDAGSYQTYATKHISPAAGYVVGWMSWLNWSATIGIELIAVSILMKRWF
HHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
PDVPSWIWCVVFAVLLFAINALSSRSFAEVEFWFASIKVITIIAFIILGGAAMFGFLDMK
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECC
GNEPAPMFSSFTDYGGLFPNGLSAILITMIAVNFSFQGTELVGIAAGESENPEKTIPKAI
CCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHH
NNTVWRILVFFVLSIFILAGLFPWQQAGVIESPFVVVFDKIGIPYAADIINFVIITAVLS
HHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHH
VANSGLYATSRMLWSMSNQGMISPIFGKLSKNGVPIYALIVSTIVGCLSLLSGIYAEDTV
HHCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHH
YLWLLSIAGFGAILVWASIALSNLLARRSYIKQGGDVKDLKFKTPLYPFVPLLALVLNVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHHH
VIVGMAFIPEQRMALYCGIPFMIVCLLFYRATRNKAHKVEHIEKTDTTEVDSL
HHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MMNQNQGLKRELKSRHIFMIALGGVIGTGLFLGSGYTIHEAGPGGAIVAYLVGGFVMYLT
CCCCCCCHHHHHHHCEEEEEEHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHH
MLCLGELAVAMPDAGSYQTYATKHISPAAGYVVGWMSWLNWSATIGIELIAVSILMKRWF
HHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
PDVPSWIWCVVFAVLLFAINALSSRSFAEVEFWFASIKVITIIAFIILGGAAMFGFLDMK
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECC
GNEPAPMFSSFTDYGGLFPNGLSAILITMIAVNFSFQGTELVGIAAGESENPEKTIPKAI
CCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHH
NNTVWRILVFFVLSIFILAGLFPWQQAGVIESPFVVVFDKIGIPYAADIINFVIITAVLS
HHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHH
VANSGLYATSRMLWSMSNQGMISPIFGKLSKNGVPIYALIVSTIVGCLSLLSGIYAEDTV
HHCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHH
YLWLLSIAGFGAILVWASIALSNLLARRSYIKQGGDVKDLKFKTPLYPFVPLLALVLNVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHHH
VIVGMAFIPEQRMALYCGIPFMIVCLLFYRATRNKAHKVEHIEKTDTTEVDSL
HHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704263; 9384377; 8550462; 8867804 [H]