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The map label for this gene is yvaE [H]

Identifier: 49183341

GI number: 49183341

Start: 336583

End: 336906

Strand: Direct

Name: yvaE [H]

Synonym: BAS0313

Alternate gene names: 49183341

Gene position: 336583-336906 (Clockwise)

Preceding gene: 49183340

Following gene: 49183346

Centisome position: 6.44

GC content: 32.1

Gene sequence:

>324_bases
ATGGTATATTGGCTATTATTACTCGTAACAATTATTTTTGAAGTAGCTGGAACAATTGCGATGAAATTATCAAATGGTTT
AACAAAGCTCGTTCCAAGTGTACTTATTTTCGTATTTTATGGAATTTGTTTCAGCGTGTTCGCCATCGTTGTAAAAAAGA
TTCATTTAAGTATTGCTTATGCAATTTGGTCTGGTGTTGGGACGTTACTTATTACAATTATTAGTGTGTACTTTTTTAAA
GAGCACATTAGCTTATTCCAAGCATGTTGTATTCTTTTTATCGTGTTAGGAGTAATTGGACTTAAGGTGTCATCTGCATC
ATAA

Upstream 100 bases:

>100_bases
ATTTCGGTATCGAGGAATATTTAGAAATTAAATATATTTCATTAGGACTATAAGTAGTATACTAGAATCTCTATAAGGTA
ACAGAGAAGGAGATTCTATT

Downstream 100 bases:

>100_bases
AAGGCTATCTTCCACTGGGGAGATAGCCTTTTACTTTTATTAAAATGCCCAATTACCTTTACGGAAGATTGGTTCATGTC
TGCCATCAGCTGTAATACCG

Product: SMR family multidrug efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 107; Mature: 107

Protein sequence:

>107_residues
MVYWLLLLVTIIFEVAGTIAMKLSNGLTKLVPSVLIFVFYGICFSVFAIVVKKIHLSIAYAIWSGVGTLLITIISVYFFK
EHISLFQACCILFIVLGVIGLKVSSAS

Sequences:

>Translated_107_residues
MVYWLLLLVTIIFEVAGTIAMKLSNGLTKLVPSVLIFVFYGICFSVFAIVVKKIHLSIAYAIWSGVGTLLITIISVYFFK
EHISLFQACCILFIVLGVIGLKVSSAS
>Mature_107_residues
MVYWLLLLVTIIFEVAGTIAMKLSNGLTKLVPSVLIFVFYGICFSVFAIVVKKIHLSIAYAIWSGVGTLLITIISVYFFK
EHISLFQACCILFIVLGVIGLKVSSAS

Specific function: Unknown

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family [H]

Homologues:

Organism=Escherichia coli, GI1787884, Length=101, Percent_Identity=34.6534653465347, Blast_Score=61, Evalue=1e-11,
Organism=Escherichia coli, GI1786755, Length=97, Percent_Identity=40.2061855670103, Blast_Score=61, Evalue=2e-11,
Organism=Escherichia coli, GI87082378, Length=102, Percent_Identity=28.4313725490196, Blast_Score=60, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11750; Mature: 11750

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVYWLLLLVTIIFEVAGTIAMKLSNGLTKLVPSVLIFVFYGICFSVFAIVVKKIHLSIAY
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIWSGVGTLLITIISVYFFKEHISLFQACCILFIVLGVIGLKVSSAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVYWLLLLVTIIFEVAGTIAMKLSNGLTKLVPSVLIFVFYGICFSVFAIVVKKIHLSIAY
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIWSGVGTLLITIISVYFFKEHISLFQACCILFIVLGVIGLKVSSAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]