Click here to switch to the map view.

The map label for this gene is appC [H]

Identifier: 49183253

GI number: 49183253

Start: 222033

End: 222956

Strand: Direct

Name: appC [H]

Synonym: BAS0220

Alternate gene names: 49183253

Gene position: 222033-222956 (Clockwise)

Preceding gene: 49183252

Following gene: 49183254

Centisome position: 4.25

GC content: 39.07

Gene sequence:

>924_bases
ATGGAGACTATTACACCAATAATAGAGAAAAAGAAAGAACGGAAAAAGAGAAATGAATCATCACCATGGCGCCAAGCGTA
TAAAAAAATCAAGAAAAATAAGATGGCGCTGTGTGGCTTATACGTTTTAATATTTATGTTTTTATTTAGTTTTATCGGTC
CAATCTTTTCACCGTATGCAGATGGGAAAGTACAAGTAACACAAATTAATAAACCGCCTAGCCTGTCACATTGGCTTGGA
ACAGACCAGTTGGGACGGGATATTTTAACTAGACTTATGCAAGCAGGGCGTATTTCATTAACAATTGGTTTAGCGTCGAT
GCTACTATCCGTTATACTAGGAGCTTTATTAGGGGCAATTGCTGGTTTTTATCGAGGGGTTGTGGATCATTTAATTATGC
GTGTTGCGGATGTGTTAATGTCCATTCCGGGATTACCGCTCCTTATTATAATGGGAGCAATTTTATCAGAATGGAAATTA
CCATCAGAATACCGTTTATATGTTGTAATGATTATTTTGAGTTTAGTAGGATGGCCAGGACTTGCTCGTCTTGTGAGAGG
ACAAATTTTAACATTGCGGGAGCAAGCCTTTATGCAAGCGGCAGATGTATTAGGATTAAAGGATTCTCGAAAAATTATTC
ATCATTTAATTCCTAATGTCTTTCCGTTGCTTATTGTTGTAGCAACCTTGGGTGTGGCTGGATCTATTTTAAGTGAGTCC
GCACTAAGTTACTTAGGTCTCGGAGTCGTCCCACCTACACCGCCATGGGGGAATATGATTAGCGCAGCGAACTCATTAAT
TGATTTTCAAAAGCGTCCGTGGTTATGGATTCCACCTGGTTTCGCAATTTTTATAACAGTTGTATCCATTAATTTACTTG
GTGATGCACTTCGTGATGCGTTAGATCCAAAGATGAGACGGTAG

Upstream 100 bases:

>100_bases
AATGTTTCTTTCTTGTTTAACAATTATGGCTAATTTCTTAGCTGATATTGTATATGCGTTTGTTGATCCAAGAATTCGAT
TGAAGTAAGGGGGGAAAGAT

Downstream 100 bases:

>100_bases
GTGAGGGAATATGAGTAAAGCGGTAGTAGAGCTGAAAGATTTACAAACACACTTTCAGACAGAAGAAGGAACAGTAAAAG
CTGTGAATCATGTTAGTTTT

Product: oligopeptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
METITPIIEKKKERKKRNESSPWRQAYKKIKKNKMALCGLYVLIFMFLFSFIGPIFSPYADGKVQVTQINKPPSLSHWLG
TDQLGRDILTRLMQAGRISLTIGLASMLLSVILGALLGAIAGFYRGVVDHLIMRVADVLMSIPGLPLLIIMGAILSEWKL
PSEYRLYVVMIILSLVGWPGLARLVRGQILTLREQAFMQAADVLGLKDSRKIIHHLIPNVFPLLIVVATLGVAGSILSES
ALSYLGLGVVPPTPPWGNMISAANSLIDFQKRPWLWIPPGFAIFITVVSINLLGDALRDALDPKMRR

Sequences:

>Translated_307_residues
METITPIIEKKKERKKRNESSPWRQAYKKIKKNKMALCGLYVLIFMFLFSFIGPIFSPYADGKVQVTQINKPPSLSHWLG
TDQLGRDILTRLMQAGRISLTIGLASMLLSVILGALLGAIAGFYRGVVDHLIMRVADVLMSIPGLPLLIIMGAILSEWKL
PSEYRLYVVMIILSLVGWPGLARLVRGQILTLREQAFMQAADVLGLKDSRKIIHHLIPNVFPLLIVVATLGVAGSILSES
ALSYLGLGVVPPTPPWGNMISAANSLIDFQKRPWLWIPPGFAIFITVVSINLLGDALRDALDPKMRR
>Mature_307_residues
METITPIIEKKKERKKRNESSPWRQAYKKIKKNKMALCGLYVLIFMFLFSFIGPIFSPYADGKVQVTQINKPPSLSHWLG
TDQLGRDILTRLMQAGRISLTIGLASMLLSVILGALLGAIAGFYRGVVDHLIMRVADVLMSIPGLPLLIIMGAILSEWKL
PSEYRLYVVMIILSLVGWPGLARLVRGQILTLREQAFMQAADVLGLKDSRKIIHHLIPNVFPLLIVVATLGVAGSILSES
ALSYLGLGVVPPTPPWGNMISAANSLIDFQKRPWLWIPPGFAIFITVVSINLLGDALRDALDPKMRR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=293, Percent_Identity=36.518771331058, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1787498, Length=305, Percent_Identity=34.7540983606557, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1787760, Length=300, Percent_Identity=31.6666666666667, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1789889, Length=248, Percent_Identity=40.3225806451613, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1789964, Length=295, Percent_Identity=36.271186440678, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1788505, Length=235, Percent_Identity=31.4893617021277, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1787549, Length=285, Percent_Identity=30.5263157894737, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34017; Mature: 34017

Theoretical pI: Translated: 10.67; Mature: 10.67

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCC
>Mature Secondary Structure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CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]