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The map label for this gene is appB [H]

Identifier: 49183252

GI number: 49183252

Start: 221097

End: 222020

Strand: Direct

Name: appB [H]

Synonym: BAS0219

Alternate gene names: 49183252

Gene position: 221097-222020 (Clockwise)

Preceding gene: 49183251

Following gene: 49183253

Centisome position: 4.23

GC content: 32.03

Gene sequence:

>924_bases
ATGATCCCTACATTGTTTGGTACATCTATTATTATTTTTTTCTTATTTGCACTTTTGCCGGGAGATTATATTGATTCAAA
TCCAAAATTAACACCAGAGAGAGCCCAAGAATTAAGGGAATTATACGGCTTAAACAAACCAATTATTGAAAGGTATTTTC
ATTGGTTAGTGAATGCTTTGCATGGTGATTTTGGATTTTCTTTACAGTATCAAGAACCGGTAACTTCATTACTTAATAAA
TTCATTTGGAATACATTTATTGTTGCTGTTGCAGCTTTATTTTTCACTTGGATTATTGCTCTTATTATTGGGGTTATTTC
TGCAACAAAGCAGCACTCTTGGTTTGATAGATTGGTAACAATCGGTGTATTTGCAGCAATGTCATTTCCATCATTCTTTA
TTGGACTATTTTTAATTAAATTATTAGCAGTTGATTTAAAGTTATTACCTATTGGTGGCATGATTGATATTGGGAGTAAC
TCAACAGGGATAGCATACATATTAGAGGTATTACGTCATATGATTCTACCTGTATTTATTTTAACGCTTCTTGGTGTAGG
ATCGTTAACACGATATTTTAGAACTGGCATGTTGGATGTTATTAGACAAGATTATATTCGTACCGCTCGTGCAAAAGGTT
TAAAAGAAAGAACCGTTATTTATAAACATGCATTGAAAAATGCAATTTTGCCAGCAATTACATTACTCGCTTTTGAATTA
CCGGGTTTATTTTCAGGAGCTATTATTATTGAACAGATTTTTAATTGGCCAGGGATTGGGAGTATTCAATTAGAAGCATT
AAACTTCCGTGATTATACGGTATTAATGGCGTTTACAATGTTTCTTTCTTGTTTAACAATTATGGCTAATTTCTTAGCTG
ATATTGTATATGCGTTTGTTGATCCAAGAATTCGATTGAAGTAA

Upstream 100 bases:

>100_bases
TGAAATGGTAGCTGTTTTGAAAAAATGTTCTTCTATTTTTAAGTAAATAGGATTGGGGAGACAAAAGGTGAAAACATATA
TCATTCGTAGGTTCCTTCAA

Downstream 100 bases:

>100_bases
GGGGGGAAAGATATGGAGACTATTACACCAATAATAGAGAAAAAGAAAGAACGGAAAAAGAGAAATGAATCATCACCATG
GCGCCAAGCGTATAAAAAAA

Product: oligopeptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MIPTLFGTSIIIFFLFALLPGDYIDSNPKLTPERAQELRELYGLNKPIIERYFHWLVNALHGDFGFSLQYQEPVTSLLNK
FIWNTFIVAVAALFFTWIIALIIGVISATKQHSWFDRLVTIGVFAAMSFPSFFIGLFLIKLLAVDLKLLPIGGMIDIGSN
STGIAYILEVLRHMILPVFILTLLGVGSLTRYFRTGMLDVIRQDYIRTARAKGLKERTVIYKHALKNAILPAITLLAFEL
PGLFSGAIIIEQIFNWPGIGSIQLEALNFRDYTVLMAFTMFLSCLTIMANFLADIVYAFVDPRIRLK

Sequences:

>Translated_307_residues
MIPTLFGTSIIIFFLFALLPGDYIDSNPKLTPERAQELRELYGLNKPIIERYFHWLVNALHGDFGFSLQYQEPVTSLLNK
FIWNTFIVAVAALFFTWIIALIIGVISATKQHSWFDRLVTIGVFAAMSFPSFFIGLFLIKLLAVDLKLLPIGGMIDIGSN
STGIAYILEVLRHMILPVFILTLLGVGSLTRYFRTGMLDVIRQDYIRTARAKGLKERTVIYKHALKNAILPAITLLAFEL
PGLFSGAIIIEQIFNWPGIGSIQLEALNFRDYTVLMAFTMFLSCLTIMANFLADIVYAFVDPRIRLK
>Mature_307_residues
MIPTLFGTSIIIFFLFALLPGDYIDSNPKLTPERAQELRELYGLNKPIIERYFHWLVNALHGDFGFSLQYQEPVTSLLNK
FIWNTFIVAVAALFFTWIIALIIGVISATKQHSWFDRLVTIGVFAAMSFPSFFIGLFLIKLLAVDLKLLPIGGMIDIGSN
STGIAYILEVLRHMILPVFILTLLGVGSLTRYFRTGMLDVIRQDYIRTARAKGLKERTVIYKHALKNAILPAITLLAFEL
PGLFSGAIIIEQIFNWPGIGSIQLEALNFRDYTVLMAFTMFLSCLTIMANFLADIVYAFVDPRIRLK

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=309, Percent_Identity=32.3624595469256, Blast_Score=201, Evalue=4e-53,
Organism=Escherichia coli, GI1789965, Length=327, Percent_Identity=33.9449541284404, Blast_Score=200, Evalue=8e-53,
Organism=Escherichia coli, GI1787497, Length=308, Percent_Identity=35.7142857142857, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1789888, Length=310, Percent_Identity=32.5806451612903, Blast_Score=160, Evalue=9e-41,
Organism=Escherichia coli, GI1787761, Length=316, Percent_Identity=31.6455696202532, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1788504, Length=295, Percent_Identity=29.8305084745763, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1787550, Length=268, Percent_Identity=28.3582089552239, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 34712; Mature: 34712

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPTLFGTSIIIFFLFALLPGDYIDSNPKLTPERAQELRELYGLNKPIIERYFHWLVNAL
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
HGDFGFSLQYQEPVTSLLNKFIWNTFIVAVAALFFTWIIALIIGVISATKQHSWFDRLVT
HCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGVFAAMSFPSFFIGLFLIKLLAVDLKLLPIGGMIDIGSNSTGIAYILEVLRHMILPVFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHH
LTLLGVGSLTRYFRTGMLDVIRQDYIRTARAKGLKERTVIYKHALKNAILPAITLLAFEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
PGLFSGAIIIEQIFNWPGIGSIQLEALNFRDYTVLMAFTMFLSCLTIMANFLADIVYAFV
CHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DPRIRLK
CCCCCCC
>Mature Secondary Structure
MIPTLFGTSIIIFFLFALLPGDYIDSNPKLTPERAQELRELYGLNKPIIERYFHWLVNAL
CCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
HGDFGFSLQYQEPVTSLLNKFIWNTFIVAVAALFFTWIIALIIGVISATKQHSWFDRLVT
HCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGVFAAMSFPSFFIGLFLIKLLAVDLKLLPIGGMIDIGSNSTGIAYILEVLRHMILPVFI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHH
LTLLGVGSLTRYFRTGMLDVIRQDYIRTARAKGLKERTVIYKHALKNAILPAITLLAFEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
PGLFSGAIIIEQIFNWPGIGSIQLEALNFRDYTVLMAFTMFLSCLTIMANFLADIVYAFV
CHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DPRIRLK
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]