Click here to switch to the map view.

The map label for this gene is infA [H]

Identifier: 49183167

GI number: 49183167

Start: 132963

End: 133181

Strand: Direct

Name: infA [H]

Synonym: BAS0133

Alternate gene names: 49183167

Gene position: 132963-133181 (Clockwise)

Preceding gene: 49183166

Following gene: 49183168

Centisome position: 2.54

GC content: 37.44

Gene sequence:

>219_bases
ATGGCTAAAGATGATGTAATTGAAGTCGAAGGTACCGTTCTTGAAACGTTGCCAAATGCTATGTTCAAAGTAGAATTAGA
GAATGGGCATGTCGTATTGGCTCACGTTTCTGGTAAAATCCGTATGAACTTCATTCGTATTTTACCAGGAGACAAAGTTA
CGGTAGAATTATCTCCGTACGATTTAAATCGTGGTCGTATTACGTACCGTTTTAAATAA

Upstream 100 bases:

>100_bases
AAGCAGGATACGAAATCCTTACCACTTTATAAGTAGCTGGCTCTCCGGGATTTCAGAGCAGTGTAAAATGTTACTGATTT
GATGAAGGGAGAACTATTGA

Downstream 100 bases:

>100_bases
TATAGCACTCCGTAATCTTTAAGGAGGTTCGAGACATGAAAGTAAGACCGTCAGTTAAACCAATCTGCGAAAAATGTAAA
GTTATTCGTAGACGTGGAAA

Product: translation initiation factor IF-1

Products: GDP; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 72; Mature: 71

Protein sequence:

>72_residues
MAKDDVIEVEGTVLETLPNAMFKVELENGHVVLAHVSGKIRMNFIRILPGDKVTVELSPYDLNRGRITYRFK

Sequences:

>Translated_72_residues
MAKDDVIEVEGTVLETLPNAMFKVELENGHVVLAHVSGKIRMNFIRILPGDKVTVELSPYDLNRGRITYRFK
>Mature_71_residues
AKDDVIEVEGTVLETLPNAMFKVELENGHVVLAHVSGKIRMNFIRILPGDKVTVELSPYDLNRGRITYRFK

Specific function: No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 [H]

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain [H]

Homologues:

Organism=Escherichia coli, GI1787110, Length=72, Percent_Identity=73.6111111111111, Blast_Score=116, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR022967
- InterPro:   IPR006196
- InterPro:   IPR004368 [H]

Pfam domain/function: PF01176 eIF-1a [H]

EC number: 3.6.5.3

Molecular weight: Translated: 8186; Mature: 8054

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: PS50832 S1_IF1_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKDDVIEVEGTVLETLPNAMFKVELENGHVVLAHVSGKIRMNFIRILPGDKVTVELSPY
CCCCCEEEECCEEEECCCCEEEEEEECCCCEEEEEECCEEEEEEEEECCCCEEEEEECCC
DLNRGRITYRFK
CCCCCEEEEEEC
>Mature Secondary Structure 
AKDDVIEVEGTVLETLPNAMFKVELENGHVVLAHVSGKIRMNFIRILPGDKVTVELSPY
CCCCEEEECCEEEECCCCEEEEEEECCCCEEEEEECCEEEEEEEEECCCCEEEEEECCC
DLNRGRITYRFK
CCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA