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The map label for this gene is yacO [H]

Identifier: 49183125

GI number: 49183125

Start: 101664

End: 102407

Strand: Direct

Name: yacO [H]

Synonym: BAS0091

Alternate gene names: 49183125

Gene position: 101664-102407 (Clockwise)

Preceding gene: 49183124

Following gene: 49183126

Centisome position: 1.94

GC content: 37.5

Gene sequence:

>744_bases
ATGAGTAGTGAATATATTATTGGACGTAACCCTGTAATTGAAGCGTTACGATCAGGGAGAGATATTAATAAAATTTGGAT
CGCAGAAGGTGCTGCCAAAGGACAAGTACAAATTGTACTAGCGCTAGCGAAAGAAAATAAGATTATTTTACAACATGCAC
CAAAAAAGAAATTAGATCAATTAGTTGAGGGGAACCATCAAGGTGTAATTGCTCAAGTGGCCGCATATCAATATGCTGAG
CTAGAAGATCTATTCAAAGTAGCAGAGAAGCGCAATGAAGATCCGTTCTTCTTAATTTTAGATGAAATTGAAGACCCGCA
TAACCTAGGTTCTATTATGCGTACTGCGGATGCAACAGGAGCTCATGGAATTATTATTCCGAAAAGAAGAGCTGTGGGAC
TTACAGCTTCAGTTGCGAAAGCATCTACCGGGGCAATTGAATATATTCCTGTTGCACGTGTAACGAATTTATCTCGTACA
ATCGATGAATTAAAAGAACGTGGACTTTGGATTGCTGGTACAGATGCAAAAGGGAAAACGGATTACCGTAATTTAGATGG
TAAAATGCCAATTGGATTAGTAATTGGAAGTGAAGGAAAAGGTATGAGCCGTATTATTGGTGAAAAATGTGATTTCTTAA
TTACTTTACCGATGGTTGGTAAAGTTACATCCTTAAATGCTTCAGTGGCCGCAAGTTTGTTAATGTATGAGGTATATCGT
AAACGTAACGAAATTGGTAAATAA

Upstream 100 bases:

>100_bases
TGATTGGCTATCATCACTTATTAAATAATCGTGAAAGATTAGACGAAATTGTATATAAGGCAATTGCTGTTTTAGAAGAA
AAGGAAGGGGGCACATCATC

Downstream 100 bases:

>100_bases
AAAATGAACGATATTTTAATCGTTGACGGTTACAACATTATTGGAGCTTGGGGAGACTTGAAAAAACTACGGGATGTAGA
TTTGCAATCATCAAGAGATG

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MSSEYIIGRNPVIEALRSGRDINKIWIAEGAAKGQVQIVLALAKENKIILQHAPKKKLDQLVEGNHQGVIAQVAAYQYAE
LEDLFKVAEKRNEDPFFLILDEIEDPHNLGSIMRTADATGAHGIIIPKRRAVGLTASVAKASTGAIEYIPVARVTNLSRT
IDELKERGLWIAGTDAKGKTDYRNLDGKMPIGLVIGSEGKGMSRIIGEKCDFLITLPMVGKVTSLNASVAASLLMYEVYR
KRNEIGK

Sequences:

>Translated_247_residues
MSSEYIIGRNPVIEALRSGRDINKIWIAEGAAKGQVQIVLALAKENKIILQHAPKKKLDQLVEGNHQGVIAQVAAYQYAE
LEDLFKVAEKRNEDPFFLILDEIEDPHNLGSIMRTADATGAHGIIIPKRRAVGLTASVAKASTGAIEYIPVARVTNLSRT
IDELKERGLWIAGTDAKGKTDYRNLDGKMPIGLVIGSEGKGMSRIIGEKCDFLITLPMVGKVTSLNASVAASLLMYEVYR
KRNEIGK
>Mature_246_residues
SSEYIIGRNPVIEALRSGRDINKIWIAEGAAKGQVQIVLALAKENKIILQHAPKKKLDQLVEGNHQGVIAQVAAYQYAEL
EDLFKVAEKRNEDPFFLILDEIEDPHNLGSIMRTADATGAHGIIIPKRRAVGLTASVAKASTGAIEYIPVARVTNLSRTI
DELKERGLWIAGTDAKGKTDYRNLDGKMPIGLVIGSEGKGMSRIIGEKCDFLITLPMVGKVTSLNASVAASLLMYEVYRK
RNEIGK

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=259, Percent_Identity=27.027027027027, Blast_Score=99, Evalue=4e-21,
Organism=Escherichia coli, GI1790623, Length=248, Percent_Identity=39.1129032258064, Blast_Score=173, Evalue=9e-45,
Organism=Escherichia coli, GI1790083, Length=159, Percent_Identity=30.188679245283, Blast_Score=86, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17555908, Length=258, Percent_Identity=29.4573643410853, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6324775, Length=165, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 27008; Mature: 26877

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSEYIIGRNPVIEALRSGRDINKIWIAEGAAKGQVQIVLALAKENKIILQHAPKKKLDQ
CCCCEEECCCHHHHHHHCCCCCCEEEEECCCCCCEEEEEEEEECCCEEEEECCCHHHHHH
LVEGNHQGVIAQVAAYQYAELEDLFKVAEKRNEDPFFLILDEIEDPHNLGSIMRTADATG
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCC
AHGIIIPKRRAVGLTASVAKASTGAIEYIPVARVTNLSRTIDELKERGLWIAGTDAKGKT
CCEEEEECCCCCCCCHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHCCCEEEECCCCCCC
DYRNLDGKMPIGLVIGSEGKGMSRIIGEKCDFLITLPMVGKVTSLNASVAASLLMYEVYR
CHHCCCCCCCEEEEECCCCCCHHHHHCCCCCEEEECCCCCCEECCCHHHHHHHHHHHHHH
KRNEIGK
HHHHCCC
>Mature Secondary Structure 
SSEYIIGRNPVIEALRSGRDINKIWIAEGAAKGQVQIVLALAKENKIILQHAPKKKLDQ
CCCEEECCCHHHHHHHCCCCCCEEEEECCCCCCEEEEEEEEECCCEEEEECCCHHHHHH
LVEGNHQGVIAQVAAYQYAELEDLFKVAEKRNEDPFFLILDEIEDPHNLGSIMRTADATG
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCCC
AHGIIIPKRRAVGLTASVAKASTGAIEYIPVARVTNLSRTIDELKERGLWIAGTDAKGKT
CCEEEEECCCCCCCCHHHHHCCCCCEEEECHHHHHHHHHHHHHHHHCCCEEEECCCCCCC
DYRNLDGKMPIGLVIGSEGKGMSRIIGEKCDFLITLPMVGKVTSLNASVAASLLMYEVYR
CHHCCCCCCCEEEEECCCCCCHHHHHCCCCCEEEECCCCCCEECCCHHHHHHHHHHHHHH
KRNEIGK
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]