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The map label for this gene is dnaX [H]

Identifier: 49183057

GI number: 49183057

Start: 25513

End: 27201

Strand: Direct

Name: dnaX [H]

Synonym: BAS0021

Alternate gene names: 49183057

Gene position: 25513-27201 (Clockwise)

Preceding gene: 49183056

Following gene: 49183058

Centisome position: 0.49

GC content: 38.9

Gene sequence:

>1689_bases
GTGTCATACCAAGCGTTATACCGAACATGGAGACCGCAAAAATTTGAAGATGTAGTCGGTCAAAAGCACGTGACAAAAAC
GTTGCAAAATGCCCTTCTTCAAGAGAAAGTTTCACATGCATATTTATTTTCTGGCCCAAGGGGAACAGGAAAAACGACAA
TTGCAAAAGTATTTGCAAAGGCAATCAACTGTGAACATGCCCCGGTAGCTGAACCTTGTAATGAATGTCCCTCTTGTTTG
GGAATTACGCAAGGGTCTATTTCAGATGTATTAGAAATTGATGCGGCTTCAAATAACGGTGTAGATGAAATTCGAGATAT
TAGAGATAAAGTAAAATATGCTCCAAGTGCTGTAGAATATAAAGTATACATTATTGATGAAGTCCACATGCTTTCTATGG
GTGCCTTCAATGCGCTTTTAAAAACGTTAGAAGAGCCGCCAGGACATGTTATCTTTATTTTGGCGACAACAGAACCGCAT
AAGATACCGCCTACAATCATTTCGCGTTGCCAACGTTTCGAATTTCGAAAAATATCAGTAAATGATATTGTTGAGAGATT
GTCGACGGTTGTGACTAATGAAGGTACGCAAGTAGAAGATGAGGCGTTACAAATTGTTGCGCGTGCCGCTGAAGGTGGTA
TGCGTGATGCGCTTAGTCTTATTGATCAGGCGATATCTTATAGTGATGAGAGGGTTACGACAGAAGATGTATTAGCTGTA
ACGGGTTCTGTTTCTCAGCAATACTTAGGCAACTTAGTAGAGTGTATACGTGAAAATGATGTATCAAGGGCGTTACGTAT
CATAGATGAGATGATGGGTAAAGGGAAAGATCCAGTTCGTTTTATGGAGGATTTCATTTACTATTATCGTGATATGCTTT
TATATCAAACTTCACCACAACTGGAACATATGTTGGAACGAGTAATGGTAGATGAGCAATTCCGTATGTTAAGTGAAGAA
ATGCAACCGGAAGTAATCTATGAAATCATTCATACTCTTAGTAAGGGACAACAGGAAATGAAGTGGACAAATCATCCGCG
AATTTTCTTAGAAGTCGTTATGGTACAACTGTGTCAACAGTTTATGATGCAAGCAAACGGTGCAGATCGTTTACAAGCAA
TTATGAACAGGATGCAGCAATTGGAGAAAGAGTTAGAACAAGTCAAAAAGAATGGTGTGCCGGTCGGTGTGCAACAGGAA
GTTAAAGAGACGCGTGCAGCACCAAAGCCAGTGCGGACAGGGAGTATGAAGATTCCTGTTGGACGTGTAAATGAAGTATT
AAAACAAGCAAAGCGTCAAGATTTAGAACAATTAAAAGCTGTGTGGGGTGAGTTACTAGGAAGACTCAAAGCATACAACA
AAGTAGCATTTGCCGTTTTATTAGAAAATAGCGAACCAGTAGCAGCTTCGGATGATACTTACGTTTTAGCGTTTCAATAT
GAGATTCACTGTAAAATGGCAAGCGAAAATCGAGAAGCTATGGATACAGTGGAACAAGCTTTATTTGAATTGCTAAGTAA
AAAATTAAATATGATTGCCATTCCAAAAAGTGAATGGGGTAAAATTCGTGAAGATTTTTTAAAACGTGAAGGTGGAAGTT
CTGAAGAAAGCCCAGAGAAAAAAGAAGATCCTCTTATAGAAGAGGCCATAAAATTAGTAGGGCAAGAACTCATTGAAATA
AAAGAGTAA

Upstream 100 bases:

>100_bases
ACTAAGGTGGGTTTTTTGTATAGAAAATAACTTTTGGAATCTATAAACAGAATGGGTTATAATAAATGAGATAATAACCT
TTGAGGGAGGCCGTATTTTC

Downstream 100 bases:

>100_bases
TAATAATTAGGAGGAATTAATTATGATGCGTGGCGGAATGGGAAATATGAATAACATGATGAAACAAATGCAAAAGATGC
AAAAGGAAATGGCAAAGGCG

Product: DNA polymerase III subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 562; Mature: 561

Protein sequence:

>562_residues
MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCL
GITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPH
KIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDERVTTEDVLAV
TGSVSQQYLGNLVECIRENDVSRALRIIDEMMGKGKDPVRFMEDFIYYYRDMLLYQTSPQLEHMLERVMVDEQFRMLSEE
MQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQQFMMQANGADRLQAIMNRMQQLEKELEQVKKNGVPVGVQQE
VKETRAAPKPVRTGSMKIPVGRVNEVLKQAKRQDLEQLKAVWGELLGRLKAYNKVAFAVLLENSEPVAASDDTYVLAFQY
EIHCKMASENREAMDTVEQALFELLSKKLNMIAIPKSEWGKIREDFLKREGGSSEESPEKKEDPLIEEAIKLVGQELIEI
KE

Sequences:

>Translated_562_residues
MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCL
GITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPH
KIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDERVTTEDVLAV
TGSVSQQYLGNLVECIRENDVSRALRIIDEMMGKGKDPVRFMEDFIYYYRDMLLYQTSPQLEHMLERVMVDEQFRMLSEE
MQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQQFMMQANGADRLQAIMNRMQQLEKELEQVKKNGVPVGVQQE
VKETRAAPKPVRTGSMKIPVGRVNEVLKQAKRQDLEQLKAVWGELLGRLKAYNKVAFAVLLENSEPVAASDDTYVLAFQY
EIHCKMASENREAMDTVEQALFELLSKKLNMIAIPKSEWGKIREDFLKREGGSSEESPEKKEDPLIEEAIKLVGQELIEI
KE
>Mature_561_residues
SYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCLG
ITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHK
IPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDERVTTEDVLAVT
GSVSQQYLGNLVECIRENDVSRALRIIDEMMGKGKDPVRFMEDFIYYYRDMLLYQTSPQLEHMLERVMVDEQFRMLSEEM
QPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQQFMMQANGADRLQAIMNRMQQLEKELEQVKKNGVPVGVQQEV
KETRAAPKPVRTGSMKIPVGRVNEVLKQAKRQDLEQLKAVWGELLGRLKAYNKVAFAVLLENSEPVAASDDTYVLAFQYE
IHCKMASENREAMDTVEQALFELLSKKLNMIAIPKSEWGKIREDFLKREGGSSEESPEKKEDPLIEEAIKLVGQELIEIK
E

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=266, Percent_Identity=27.0676691729323, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI194306571, Length=266, Percent_Identity=27.0676691729323, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI194306567, Length=266, Percent_Identity=27.0676691729323, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI31563534, Length=285, Percent_Identity=26.6666666666667, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI194306569, Length=186, Percent_Identity=28.494623655914, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI4506491, Length=368, Percent_Identity=20.9239130434783, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI31881687, Length=368, Percent_Identity=20.9239130434783, Blast_Score=73, Evalue=8e-13,
Organism=Escherichia coli, GI1786676, Length=358, Percent_Identity=43.5754189944134, Blast_Score=297, Evalue=1e-81,
Organism=Escherichia coli, GI1787119, Length=306, Percent_Identity=25.1633986928105, Blast_Score=70, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71986063, Length=295, Percent_Identity=23.728813559322, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17554730, Length=225, Percent_Identity=27.1111111111111, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17541988, Length=237, Percent_Identity=28.6919831223629, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324039, Length=309, Percent_Identity=24.9190938511327, Blast_Score=88, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6322528, Length=309, Percent_Identity=23.3009708737864, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324478, Length=222, Percent_Identity=25.6756756756757, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI18859927, Length=290, Percent_Identity=22.4137931034483, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17647857, Length=314, Percent_Identity=25.4777070063694, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI19921076, Length=237, Percent_Identity=24.8945147679325, Blast_Score=83, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 63793; Mature: 63662

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAK
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHH
AINCEHAPVAEPCNECPSCLGITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEY
HHCCCCCCCCCHHHHCHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEE
KVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTIISRCQRFEFRKISV
EEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCH
NDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDERVTTEDVLAV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
TGSVSQQYLGNLVECIRENDVSRALRIIDEMMGKGKDPVRFMEDFIYYYRDMLLYQTSPQ
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHH
LEHMLERVMVDEQFRMLSEEMQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQQ
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHH
FMMQANGADRLQAIMNRMQQLEKELEQVKKNGVPVGVQQEVKETRAAPKPVRTGSMKIPV
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCH
GRVNEVLKQAKRQDLEQLKAVWGELLGRLKAYNKVAFAVLLENSEPVAASDDTYVLAFQY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCEEEEEEE
EIHCKMASENREAMDTVEQALFELLSKKLNMIAIPKSEWGKIREDFLKREGGSSEESPEK
EEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCC
KEDPLIEEAIKLVGQELIEIKE
CCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAK
CCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHH
AINCEHAPVAEPCNECPSCLGITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEY
HHCCCCCCCCCHHHHCHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEE
KVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTIISRCQRFEFRKISV
EEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCH
NDIVERLSTVVTNEGTQVEDEALQIVARAAEGGMRDALSLIDQAISYSDERVTTEDVLAV
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
TGSVSQQYLGNLVECIRENDVSRALRIIDEMMGKGKDPVRFMEDFIYYYRDMLLYQTSPQ
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHH
LEHMLERVMVDEQFRMLSEEMQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQQ
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHH
FMMQANGADRLQAIMNRMQQLEKELEQVKKNGVPVGVQQEVKETRAAPKPVRTGSMKIPV
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCH
GRVNEVLKQAKRQDLEQLKAVWGELLGRLKAYNKVAFAVLLENSEPVAASDDTYVLAFQY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCEEEEEEE
EIHCKMASENREAMDTVEQALFELLSKKLNMIAIPKSEWGKIREDFLKREGGSSEESPEK
EEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCC
KEDPLIEEAIKLVGQELIEIKE
CCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]