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The map label for this gene is lspA [H]

Identifier: 46447431

GI number: 46447431

Start: 2150845

End: 2151372

Strand: Reverse

Name: lspA [H]

Synonym: pc1797

Alternate gene names: 46447431

Gene position: 2151372-2150845 (Counterclockwise)

Preceding gene: 46447432

Following gene: 46447430

Centisome position: 89.1

GC content: 35.61

Gene sequence:

>528_bases
ATGAATGAATATTTCTCAGTTATACCAACTCATAAAAATCAATTACTCTTTCGCTTTATCTGGATAGGGTTAGCTATTTT
ATTATTGGATCAGATCTCAAAATTCTTCGTTTTCCATCTTGTTCCTCACATGGATTTTTCTGCATATAAGTATCCTTATG
GAGGGGTGGAAGTCGTGAGGAATTTTGGGGGAATTGAGTTTTCGATCAACCACATGACGAATAAAGGGGCTGCCTGGGGA
ATGTTTGGGAATTACCAGTTGTCTCTGATGCTCTTTCGTATAGGATTGATTGTTGGGTTGTGTGTGTACTTGTTTCATTT
TAACCAACAAAAAGCCTGGCAAATTCCTTTGATTTTAATTATCGCAGGAGCAATTGGTAACGTCTTGGATTTCTTTTTTT
ATGGACATGTGGTGGATATGCTTCATTTCGTATTATGGGGATATGACTTTCCTGTTTTTAATGTTGCCGATAGCTTTATT
TCAATTGGCATTGGTTTATTGTTTATTCTTTCTTTGTTTAAGTCTTAA

Upstream 100 bases:

>100_bases
ATTCCTATTGCGCGATTAGACGCTGTTCCTTACGCGGTTATGACTGTTAAAGCACAAGAAAAATTTGAAAAAGGTTTGCT
ATAGGACTTAAGTTAAGTAA

Downstream 100 bases:

>100_bases
CGGTGCCCATGTATCCTTCCTTACCTATTCGTACAAAAGTGGAATCCCCTTTTCAAGCTTCAAGATGGTTGCAATGCCCA
GTCTTATTAGATGAAGAAGA

Product: putative signal peptidase II (prolipoprotein signal peptidase)

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 175; Mature: 175

Protein sequence:

>175_residues
MNEYFSVIPTHKNQLLFRFIWIGLAILLLDQISKFFVFHLVPHMDFSAYKYPYGGVEVVRNFGGIEFSINHMTNKGAAWG
MFGNYQLSLMLFRIGLIVGLCVYLFHFNQQKAWQIPLILIIAGAIGNVLDFFFYGHVVDMLHFVLWGYDFPVFNVADSFI
SIGIGLLFILSLFKS

Sequences:

>Translated_175_residues
MNEYFSVIPTHKNQLLFRFIWIGLAILLLDQISKFFVFHLVPHMDFSAYKYPYGGVEVVRNFGGIEFSINHMTNKGAAWG
MFGNYQLSLMLFRIGLIVGLCVYLFHFNQQKAWQIPLILIIAGAIGNVLDFFFYGHVVDMLHFVLWGYDFPVFNVADSFI
SIGIGLLFILSLFKS
>Mature_175_residues
MNEYFSVIPTHKNQLLFRFIWIGLAILLLDQISKFFVFHLVPHMDFSAYKYPYGGVEVVRNFGGIEFSINHMTNKGAAWG
MFGNYQLSLMLFRIGLIVGLCVYLFHFNQQKAWQIPLILIIAGAIGNVLDFFFYGHVVDMLHFVLWGYDFPVFNVADSFI
SIGIGLLFILSLFKS

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 20135; Mature: 20135

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEYFSVIPTHKNQLLFRFIWIGLAILLLDQISKFFVFHLVPHMDFSAYKYPYGGVEVVR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
NFGGIEFSINHMTNKGAAWGMFGNYQLSLMLFRIGLIVGLCVYLFHFNQQKAWQIPLILI
HCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
IAGAIGNVLDFFFYGHVVDMLHFVLWGYDFPVFNVADSFISIGIGLLFILSLFKS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNEYFSVIPTHKNQLLFRFIWIGLAILLLDQISKFFVFHLVPHMDFSAYKYPYGGVEVVR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
NFGGIEFSINHMTNKGAAWGMFGNYQLSLMLFRIGLIVGLCVYLFHFNQQKAWQIPLILI
HCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
IAGAIGNVLDFFFYGHVVDMLHFVLWGYDFPVFNVADSFISIGIGLLFILSLFKS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]