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The map label for this gene is gmhA [H]

Identifier: 46447421

GI number: 46447421

Start: 2142690

End: 2143334

Strand: Reverse

Name: gmhA [H]

Synonym: pc1787

Alternate gene names: 46447421

Gene position: 2143334-2142690 (Counterclockwise)

Preceding gene: 46447425

Following gene: 46447420

Centisome position: 88.77

GC content: 36.43

Gene sequence:

>645_bases
GTGAGTCAAAATAATGATACCATTTTTATAATTTACTTTATCAATTCAATCTTCAGATCTCTTGATATGCAAACTAATTT
ATTAGACGCAATCGATGATTGCATAAAAGCCGTTGAACAACTCAAACTTCCTTCTTCAATTAATTTTATAGAACAGACCG
CTCTTCTTTTAGCTACGTGTTTCCAAAATGGGGGTAAAATTATTCTTGCTGGGAATGGAGGAAGTTTGTGTGATGCTTGC
CATTTTGCTGAAGAATTAACAGGGTATTTCAGAAAAGCACGGCGACCTCTGCCAGCCATTGCTTTATCTGAACCTGGGCA
TATCACTTGTACTGCCAATGACAAAGGATTTGAATGGATCTTTTCAAGAGGCGTAGAGGCTTATGGTAAAACTGGCGACG
TTTTTATCGGTCTCACAACAAGTGGAAATTCTCTAAATATAATTCGTGCTTTTGAGCAGGCAAAAAAACAAAGTATGCAT
ACGATTGCGTTTTTAGGAAAAGACGGAGGAGTGTTGAAAGATGTTGCTGATTTCGAATTAATTATTCAGGGATTTCAAAC
ATCGGATCGCATTCAAGAAGCTCATATGGCAGCTATCCATCTCATAATCGAATTAGTTGAAGTGCATTTATTTGCAAAAA
ATTAA

Upstream 100 bases:

>100_bases
ATCCTTATTAGTTAGCATCATAAAGAAATTCTAAAAAACATCTTATATTTAAAAAAAACACAGTTTAAGAAAAAGGAAAA
CCCTTGCTTCTTAACGAAGA

Downstream 100 bases:

>100_bases
ATTTTATCAAATGTTAATGATTGGGAGTTTTTAAAATTTTATCATTCATTTTTATCGAGCTTAATAAGGTTTTTTGCATG
TTTTTGAGAAAAATTGAAAT

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MSQNNDTIFIIYFINSIFRSLDMQTNLLDAIDDCIKAVEQLKLPSSINFIEQTALLLATCFQNGGKIILAGNGGSLCDAC
HFAEELTGYFRKARRPLPAIALSEPGHITCTANDKGFEWIFSRGVEAYGKTGDVFIGLTTSGNSLNIIRAFEQAKKQSMH
TIAFLGKDGGVLKDVADFELIIQGFQTSDRIQEAHMAAIHLIIELVEVHLFAKN

Sequences:

>Translated_214_residues
MSQNNDTIFIIYFINSIFRSLDMQTNLLDAIDDCIKAVEQLKLPSSINFIEQTALLLATCFQNGGKIILAGNGGSLCDAC
HFAEELTGYFRKARRPLPAIALSEPGHITCTANDKGFEWIFSRGVEAYGKTGDVFIGLTTSGNSLNIIRAFEQAKKQSMH
TIAFLGKDGGVLKDVADFELIIQGFQTSDRIQEAHMAAIHLIIELVEVHLFAKN
>Mature_213_residues
SQNNDTIFIIYFINSIFRSLDMQTNLLDAIDDCIKAVEQLKLPSSINFIEQTALLLATCFQNGGKIILAGNGGSLCDACH
FAEELTGYFRKARRPLPAIALSEPGHITCTANDKGFEWIFSRGVEAYGKTGDVFIGLTTSGNSLNIIRAFEQAKKQSMHT
IAFLGKDGGVLKDVADFELIIQGFQTSDRIQEAHMAAIHLIIELVEVHLFAKN

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1786416, Length=167, Percent_Identity=50.8982035928144, Blast_Score=177, Evalue=3e-46,
Organism=Escherichia coli, GI1789539, Length=173, Percent_Identity=35.8381502890173, Blast_Score=105, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004515
- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 23559; Mature: 23428

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQNNDTIFIIYFINSIFRSLDMQTNLLDAIDDCIKAVEQLKLPSSINFIEQTALLLATC
CCCCCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
FQNGGKIILAGNGGSLCDACHFAEELTGYFRKARRPLPAIALSEPGHITCTANDKGFEWI
HCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEECCCCHHHH
FSRGVEAYGKTGDVFIGLTTSGNSLNIIRAFEQAKKQSMHTIAFLGKDGGVLKDVADFEL
HHCCHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHH
IIQGFQTSDRIQEAHMAAIHLIIELVEVHLFAKN
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SQNNDTIFIIYFINSIFRSLDMQTNLLDAIDDCIKAVEQLKLPSSINFIEQTALLLATC
CCCCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
FQNGGKIILAGNGGSLCDACHFAEELTGYFRKARRPLPAIALSEPGHITCTANDKGFEWI
HCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEEECCCCHHHH
FSRGVEAYGKTGDVFIGLTTSGNSLNIIRAFEQAKKQSMHTIAFLGKDGGVLKDVADFEL
HHCCHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHH
IIQGFQTSDRIQEAHMAAIHLIIELVEVHLFAKN
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]