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The map label for this gene is trxB [H]

Identifier: 46447347

GI number: 46447347

Start: 2051352

End: 2052302

Strand: Reverse

Name: trxB [H]

Synonym: pc1713

Alternate gene names: 46447347

Gene position: 2052302-2051352 (Counterclockwise)

Preceding gene: 46447351

Following gene: 46447346

Centisome position: 85.0

GC content: 38.59

Gene sequence:

>951_bases
ATGGAAAAAGCAAAGCTAATTATTATTGGATCTGGGCCCGCAGGATATACAGCTGCTATTTATGCTGCTCGAGCTAACTT
AGAGCCTATTTTATTTGAAGGATTTTTTACAGGCGCTGCAGGGGGTCAATTGATGACAACAACTGAGGTAGAAAATTTTC
CTGGCTTTCCTGATGGAATTACAGGACCCGAGCTAGTCGATCGTTTTCGACAACAGGCCATTCGTTTTGGAACAACTATA
ATTAGTGAGGATGTAGACTCTGTTGATTTTCAAGTTTACCCTTTTATTATTAAAGGTAAGAAATCGCATTATCAAGCTAG
TTCTGTTATTGTCTCTACTGGAGCTACAGCAAAACGTTTACCCATTCCAGGCGCAGGTGATGATGAATTTTGGCAAAAAG
GTGTGACAGCTTGTGCTGTCTGTGATGGGGCGGCTCCTATTTTTCGCAATCGCCCTTTATTTGTCATAGGTGGAGGAGAT
TCAGCCATTGAAGAAGCCACATTTTTGACAAAGTTTGGAAGTCGTGTTTTTATTGTTCATCGAAGAGATACATTACGAGC
TTCTAAAATCATGCAGGAAAGAGCCTTTAATAACCCTAAAATTGAAATGATTTGGAATTCAGAAGTTATTCAAGTAAAGG
GAGACCAAATCGTAAAAAATCTTGTGATTAGAAATGTCAAAACAGGACAGGAAAAAGAATATGAAGCAGCAGGACTTTTT
TTCGCGATTGGACATAATCCAAATACTGAGTTTTTAAAAAATCAATTGGAATTACATTCGAATGGTTACTTAAAAGTTTT
CAAAGGAACCCAAACAAGCATTAAAGGCGTATTTGCAGCAGGAGATGTTCAAGATTTTGAATATCGGCAAGCTATTACTG
CTGCAGGTAGTGGTTGTATGGCAGCCTTGGATGCTGAAAGATGGCTCGCTGAAAAAGGATTAGACAATTAA

Upstream 100 bases:

>100_bases
TTTTAAGAGATATTAATTGATAATAATATTCTCTTTTTTTCTCCTTTATGATACGGATATGAATCAGTAAATATAAAATT
TAAATTGGTTAGGAAAGAAA

Downstream 100 bases:

>100_bases
TGTTTTTCAGAAAAATTTGGAAATGGTTATTTTGTGTTTATTTATTACCAATTCTAGGCTGGGCTTATGAAGATCAGCCT
TGGATAGGCAATTATCTTGA

Product: thioredoxin-disulfide reductase 2

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MEKAKLIIIGSGPAGYTAAIYAARANLEPILFEGFFTGAAGGQLMTTTEVENFPGFPDGITGPELVDRFRQQAIRFGTTI
ISEDVDSVDFQVYPFIIKGKKSHYQASSVIVSTGATAKRLPIPGAGDDEFWQKGVTACAVCDGAAPIFRNRPLFVIGGGD
SAIEEATFLTKFGSRVFIVHRRDTLRASKIMQERAFNNPKIEMIWNSEVIQVKGDQIVKNLVIRNVKTGQEKEYEAAGLF
FAIGHNPNTEFLKNQLELHSNGYLKVFKGTQTSIKGVFAAGDVQDFEYRQAITAAGSGCMAALDAERWLAEKGLDN

Sequences:

>Translated_316_residues
MEKAKLIIIGSGPAGYTAAIYAARANLEPILFEGFFTGAAGGQLMTTTEVENFPGFPDGITGPELVDRFRQQAIRFGTTI
ISEDVDSVDFQVYPFIIKGKKSHYQASSVIVSTGATAKRLPIPGAGDDEFWQKGVTACAVCDGAAPIFRNRPLFVIGGGD
SAIEEATFLTKFGSRVFIVHRRDTLRASKIMQERAFNNPKIEMIWNSEVIQVKGDQIVKNLVIRNVKTGQEKEYEAAGLF
FAIGHNPNTEFLKNQLELHSNGYLKVFKGTQTSIKGVFAAGDVQDFEYRQAITAAGSGCMAALDAERWLAEKGLDN
>Mature_316_residues
MEKAKLIIIGSGPAGYTAAIYAARANLEPILFEGFFTGAAGGQLMTTTEVENFPGFPDGITGPELVDRFRQQAIRFGTTI
ISEDVDSVDFQVYPFIIKGKKSHYQASSVIVSTGATAKRLPIPGAGDDEFWQKGVTACAVCDGAAPIFRNRPLFVIGGGD
SAIEEATFLTKFGSRVFIVHRRDTLRASKIMQERAFNNPKIEMIWNSEVIQVKGDQIVKNLVIRNVKTGQEKEYEAAGLF
FAIGHNPNTEFLKNQLELHSNGYLKVFKGTQTSIKGVFAAGDVQDFEYRQAITAAGSGCMAALDAERWLAEKGLDN

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=318, Percent_Identity=49.3710691823899, Blast_Score=293, Evalue=7e-81,
Organism=Escherichia coli, GI87081763, Length=317, Percent_Identity=32.807570977918, Blast_Score=138, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6320560, Length=317, Percent_Identity=55.205047318612, Blast_Score=357, Evalue=1e-99,
Organism=Saccharomyces cerevisiae, GI6321898, Length=318, Percent_Identity=51.8867924528302, Blast_Score=338, Evalue=8e-94,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34474; Mature: 34474

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKAKLIIIGSGPAGYTAAIYAARANLEPILFEGFFTGAAGGQLMTTTEVENFPGFPDGI
CCCEEEEEEECCCCCCEEEEEEECCCCCEEEEEEEECCCCCCEEEEEEECCCCCCCCCCC
TGPELVDRFRQQAIRFGTTIISEDVDSVDFQVYPFIIKGKKSHYQASSVIVSTGATAKRL
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCEECEEEEECCCCCCCC
PIPGAGDDEFWQKGVTACAVCDGAAPIFRNRPLFVIGGGDSAIEEATFLTKFGSRVFIVH
CCCCCCCHHHHHCCCCEEEEECCCCHHHCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEE
RRDTLRASKIMQERAFNNPKIEMIWNSEVIQVKGDQIVKNLVIRNVKTGQEKEYEAAGLF
CCCHHHHHHHHHHHCCCCCCEEEEECCEEEEECHHHHHHHHHHHCCCCCCCCCEEECEEE
FAIGHNPNTEFLKNQLELHSNGYLKVFKGTQTSIKGVFAAGDVQDFEYRQAITAAGSGCM
EEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHCCCCCE
AALDAERWLAEKGLDN
EEHHHHHHHHHCCCCC
>Mature Secondary Structure
MEKAKLIIIGSGPAGYTAAIYAARANLEPILFEGFFTGAAGGQLMTTTEVENFPGFPDGI
CCCEEEEEEECCCCCCEEEEEEECCCCCEEEEEEEECCCCCCEEEEEEECCCCCCCCCCC
TGPELVDRFRQQAIRFGTTIISEDVDSVDFQVYPFIIKGKKSHYQASSVIVSTGATAKRL
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCEECEEEEECCCCCCCC
PIPGAGDDEFWQKGVTACAVCDGAAPIFRNRPLFVIGGGDSAIEEATFLTKFGSRVFIVH
CCCCCCCHHHHHCCCCEEEEECCCCHHHCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEE
RRDTLRASKIMQERAFNNPKIEMIWNSEVIQVKGDQIVKNLVIRNVKTGQEKEYEAAGLF
CCCHHHHHHHHHHHCCCCCCEEEEECCEEEEECHHHHHHHHHHHCCCCCCCCCEEECEEE
FAIGHNPNTEFLKNQLELHSNGYLKVFKGTQTSIKGVFAAGDVQDFEYRQAITAAGSGCM
EEECCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCHHHHHHHHHHCCCCCE
AALDAERWLAEKGLDN
EEHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]