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The map label for this gene is mreB [H]

Identifier: 46447006

GI number: 46447006

Start: 1642725

End: 1643816

Strand: Reverse

Name: mreB [H]

Synonym: pc1372

Alternate gene names: 46447006

Gene position: 1643816-1642725 (Counterclockwise)

Preceding gene: 46447007

Following gene: 46447005

Centisome position: 68.08

GC content: 42.03

Gene sequence:

>1092_bases
ATGACTAAAAAAAATCAAGCCAGTTTTACAGGCATGGCTAATCAACTATATCGTTCTGCATTTGGACAGCTTAATAAGTT
TAGAGGGGTTTTTTCTAACGATATAGGGATCGACCTAGGAACTGCCAATACACTGGTTTTTGTGAGAGGAAAAGGAATTG
TTTTGGCTGAACCTTCCGTGGTTGCTGTCGACTCGGTGACAAATGAGGTATTGGCTGTTGGTCATAAAGCTAAGGCGATG
CTTGGTAAAACTCCTCGTAGGATCCATGCTGTAAGGCCTATGAAGGATGGCGTTATCGCCGATTTCGAAATTGCAGAGGG
AATGCTAAAAGCTTTAATCAGAAGGGTAACGCCTTCACGGAGTTTATTCAGACCAAAGATTCTTATTGCGGTTCCTTCCG
GAATCACAGGTGTTGAAAAAAGGGCAGTTGAAGACTCGGCTCTTCACGCTGGGGCCCAAGAAGTTTTTTTGATTGAAGAA
CCGATGGCTGCGGCAATTGGTGTGGACCTTCCAGTACACGAAGCTTGCGCGAGCATGATTATTGATGTTGGAGGAGGGAC
AACCGAAATTGCGATTTTGTCGCTTGGAGGAATTGTTGAATCTCGCTCGCTACGCATTGCAGGAGATGAATTTGATGAAT
GTATCATCAATTATATGAGACGTACTTATAATTTAATGATTGGTCCTCGTACGGCAGAAGAAATAAAAATCACCATTGGT
TCAGCTTATCCTCTTGGTGGAAATGAATTGGAAATGGAAGTGCGTGGGCGAGATCAAGTTGCAGGACTACCTGTTACTAA
ACGCATTAACTCTGTTGAGATCCGAGAATGTTTAGCAGAACCTATTCAACAGGTTGTGGAAAGTGTTAAATTGACTCTTG
AAAAATGTCCTCCTGAATTAGCTGCTGATCTTGTTGAACGAGGAATGGTGTTGGCCGGAGGTGGTGCGCTGATTAAAGGT
TTAGATAAAGCTTTGATTAAAGAGACAGGTTTACCTGTTATTGTTGCCCCTAACCCTTTATTAGCAGTTTGTTTAGGAAC
AGGAAAAGCCCTTGAGTACTTAGATAAATTTAAAAAACGTAAAGCAATTTGA

Upstream 100 bases:

>100_bases
ATTTATTATGTAGTTAAATTAAAATAAATTCCAACACCACAAATAATGAATAAGGGATTTATAGCAAACAACGGGGGGTT
GAATCCCGATGGGAAAAACA

Downstream 100 bases:

>100_bases
GTTTTTTAAGAGGAATTTTTCAGCATGAAATATGAAGAATTAAAACCTTGGATTCAAGAAATCGCTGAACTTTGTCAACC
TCAAATTGTGCATATTTGCG

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MTKKNQASFTGMANQLYRSAFGQLNKFRGVFSNDIGIDLGTANTLVFVRGKGIVLAEPSVVAVDSVTNEVLAVGHKAKAM
LGKTPRRIHAVRPMKDGVIADFEIAEGMLKALIRRVTPSRSLFRPKILIAVPSGITGVEKRAVEDSALHAGAQEVFLIEE
PMAAAIGVDLPVHEACASMIIDVGGGTTEIAILSLGGIVESRSLRIAGDEFDECIINYMRRTYNLMIGPRTAEEIKITIG
SAYPLGGNELEMEVRGRDQVAGLPVTKRINSVEIRECLAEPIQQVVESVKLTLEKCPPELAADLVERGMVLAGGGALIKG
LDKALIKETGLPVIVAPNPLLAVCLGTGKALEYLDKFKKRKAI

Sequences:

>Translated_363_residues
MTKKNQASFTGMANQLYRSAFGQLNKFRGVFSNDIGIDLGTANTLVFVRGKGIVLAEPSVVAVDSVTNEVLAVGHKAKAM
LGKTPRRIHAVRPMKDGVIADFEIAEGMLKALIRRVTPSRSLFRPKILIAVPSGITGVEKRAVEDSALHAGAQEVFLIEE
PMAAAIGVDLPVHEACASMIIDVGGGTTEIAILSLGGIVESRSLRIAGDEFDECIINYMRRTYNLMIGPRTAEEIKITIG
SAYPLGGNELEMEVRGRDQVAGLPVTKRINSVEIRECLAEPIQQVVESVKLTLEKCPPELAADLVERGMVLAGGGALIKG
LDKALIKETGLPVIVAPNPLLAVCLGTGKALEYLDKFKKRKAI
>Mature_362_residues
TKKNQASFTGMANQLYRSAFGQLNKFRGVFSNDIGIDLGTANTLVFVRGKGIVLAEPSVVAVDSVTNEVLAVGHKAKAML
GKTPRRIHAVRPMKDGVIADFEIAEGMLKALIRRVTPSRSLFRPKILIAVPSGITGVEKRAVEDSALHAGAQEVFLIEEP
MAAAIGVDLPVHEACASMIIDVGGGTTEIAILSLGGIVESRSLRIAGDEFDECIINYMRRTYNLMIGPRTAEEIKITIGS
AYPLGGNELEMEVRGRDQVAGLPVTKRINSVEIRECLAEPIQQVVESVKLTLEKCPPELAADLVERGMVLAGGGALIKGL
DKALIKETGLPVIVAPNPLLAVCLGTGKALEYLDKFKKRKAI

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=339, Percent_Identity=58.9970501474926, Blast_Score=381, Evalue=1e-107,
Organism=Escherichia coli, GI1788875, Length=228, Percent_Identity=28.5087719298246, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 38890; Mature: 38759

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKNQASFTGMANQLYRSAFGQLNKFRGVFSNDIGIDLGTANTLVFVRGKGIVLAEPSV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHCCCCCEEECCCCEEEEEECCEEEEECCCE
VAVDSVTNEVLAVGHKAKAMLGKTPRRIHAVRPMKDGVIADFEIAEGMLKALIRRVTPSR
EEEHHHHHHHHHHCCHHHHHHCCCCHHHEECCCCCCCCEECHHHHHHHHHHHHHHCCCCC
SLFRPKILIAVPSGITGVEKRAVEDSALHAGAQEVFLIEEPMAAAIGVDLPVHEACASMI
HHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHCCCCCHHHHHHHHE
IDVGGGTTEIAILSLGGIVESRSLRIAGDEFDECIINYMRRTYNLMIGPRTAEEIKITIG
EECCCCCEEEEEEEECCEEECCCEEECCCHHHHHHHHHHHHHHEEEECCCCCCEEEEEEE
SAYPLGGNELEMEVRGRDQVAGLPVTKRINSVEIRECLAEPIQQVVESVKLTLEKCPPEL
CCCCCCCCEEEEEECCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
AADLVERGMVLAGGGALIKGLDKALIKETGLPVIVAPNPLLAVCLGTGKALEYLDKFKKR
HHHHHHCCEEEECCCHHHHHHHHHHHHHCCCCEEECCCCEEEEEECCCHHHHHHHHHHHH
KAI
CCC
>Mature Secondary Structure 
TKKNQASFTGMANQLYRSAFGQLNKFRGVFSNDIGIDLGTANTLVFVRGKGIVLAEPSV
CCCCCCHHHHHHHHHHHHHHHHHHHHHCHHCCCCCEEECCCCEEEEEECCEEEEECCCE
VAVDSVTNEVLAVGHKAKAMLGKTPRRIHAVRPMKDGVIADFEIAEGMLKALIRRVTPSR
EEEHHHHHHHHHHCCHHHHHHCCCCHHHEECCCCCCCCEECHHHHHHHHHHHHHHCCCCC
SLFRPKILIAVPSGITGVEKRAVEDSALHAGAQEVFLIEEPMAAAIGVDLPVHEACASMI
HHCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCHHHHCCCCCHHHHHHHHE
IDVGGGTTEIAILSLGGIVESRSLRIAGDEFDECIINYMRRTYNLMIGPRTAEEIKITIG
EECCCCCEEEEEEEECCEEECCCEEECCCHHHHHHHHHHHHHHEEEECCCCCCEEEEEEE
SAYPLGGNELEMEVRGRDQVAGLPVTKRINSVEIRECLAEPIQQVVESVKLTLEKCPPEL
CCCCCCCCEEEEEECCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
AADLVERGMVLAGGGALIKGLDKALIKETGLPVIVAPNPLLAVCLGTGKALEYLDKFKKR
HHHHHHCCEEEECCCHHHHHHHHHHHHHCCCCEEECCCCEEEEEECCCHHHHHHHHHHHH
KAI
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]