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The map label for this gene is atoS [H]

Identifier: 46446999

GI number: 46446999

Start: 1635004

End: 1636236

Strand: Reverse

Name: atoS [H]

Synonym: pc1365

Alternate gene names: 46446999

Gene position: 1636236-1635004 (Counterclockwise)

Preceding gene: 46447004

Following gene: 46446998

Centisome position: 67.77

GC content: 35.36

Gene sequence:

>1233_bases
GTGCGAATGGGGCAGGCTTTTAAGCAATTTTCTTTGGAAACAGAACGATTAGAATTTGCTTATCAAAGTTTGCAAGAGCA
GTTTAAAAGTGTTCAAAAAAGTTTGCAAGAGTCACATACGAAACATTCAGGAAAGCTAGCAGAATTAGATTTTGTCACGC
GTTATTTAGAAACAATTCTTAACCATATCTCACAAGGAATCCTTTTTGTTGATCTTAATGGAATTATTACGACTTGTAAT
ACAAAAACGGAAGAAATTTTGAAAGTGCAGGCCAGTCGGCTTCTTTTTCATTCATTTAGTGATTGTTTTGAAGATATGGC
CTTTGGATTTTCTATTCAGGAAGTTTTACAAACAAAAACTTGTCCTCGCATTTGTTTTGTGACACGAGCTTTAGAAAATG
ATTTAAAAGTTGAATTAGAAATTGAACCGACTTTTGTTTCGATGAGCGAGCACTCTTTTCCATTAGATCATCGGCAACCT
TCTTCCCCTCCTGTTCAAGGACTTTTAATTTTAATTCGTAACATCACAGAAGTTAGAAGTTTGCAGCAAGCGGCTAATCA
ATACAGTCGTCTAAAAGAATTAGGAGAAATGGCGGCTCATTTAGCTCATGAAATTCGAAATCCTCTAGGGGGTATTAAAG
GATTTGCCACCCTTCTTCAGCAAGATTTAGCAGATCGACCCGAACTTCAACAAATGGCTTATCATATTATCGAAGGAACC
GATAGTCTAAATCATTTTGTATCAAGTATTCTAACATATACAAGACCCTTTCAAGCTCGTTTTGAACATGTCAATTTGAA
AACTTACTTAGAAGAAATCGGACTTCTTTTACAAGCTGACGTGAGTTGGAACGCTTCATTCTCATTCAATCTCAATACTC
ATCTACCAGATCTTGTCCTTTCAATAGATCCTCCTTTATTAAAATCAGCAATTTTAAATTTGTTGGTTAATGCTATGCAA
GCGATGCCGCAAGGCGGAAAAATTACTGTCTCGGTAGAAAAAATGCAAGATGAAGTCGTCATCATTATTTCTGATACAGG
AATTGGAATTTCTAAAGAAAATTTAAATAAAATCTTTTCCCCCTTTTTTACAACCAAAGAAACAGGGACTGGTTTAGGGT
TGGCAGAGGTTCAAAAAGTTATTCAGGCGCATCAAGGAACAATTGAAGTAAAATCTGAAGTTGGTAATGGAACTTCTTTT
ACTATCAAACTTCCTTTAAAAGTCGTTCAATAA

Upstream 100 bases:

>100_bases
AGCCTATTGCGTAGATTATATATTGCGTTATGTGAAGGTCCTTTAACGGTGAGAATAGATGGCAGAGCGATCAGAGTTTA
AAATGGAAGAAAAAGAAGAT

Downstream 100 bases:

>100_bases
ATCATTCAATGTAAGGGCAAAATTATGACCATTGAAAAAATTTTAATTGTTGATGATGAATTGATTATGCGAAACTTTCT
TACAGAAGCTCTGAAACGAA

Product: putative two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MRMGQAFKQFSLETERLEFAYQSLQEQFKSVQKSLQESHTKHSGKLAELDFVTRYLETILNHISQGILFVDLNGIITTCN
TKTEEILKVQASRLLFHSFSDCFEDMAFGFSIQEVLQTKTCPRICFVTRALENDLKVELEIEPTFVSMSEHSFPLDHRQP
SSPPVQGLLILIRNITEVRSLQQAANQYSRLKELGEMAAHLAHEIRNPLGGIKGFATLLQQDLADRPELQQMAYHIIEGT
DSLNHFVSSILTYTRPFQARFEHVNLKTYLEEIGLLLQADVSWNASFSFNLNTHLPDLVLSIDPPLLKSAILNLLVNAMQ
AMPQGGKITVSVEKMQDEVVIIISDTGIGISKENLNKIFSPFFTTKETGTGLGLAEVQKVIQAHQGTIEVKSEVGNGTSF
TIKLPLKVVQ

Sequences:

>Translated_410_residues
MRMGQAFKQFSLETERLEFAYQSLQEQFKSVQKSLQESHTKHSGKLAELDFVTRYLETILNHISQGILFVDLNGIITTCN
TKTEEILKVQASRLLFHSFSDCFEDMAFGFSIQEVLQTKTCPRICFVTRALENDLKVELEIEPTFVSMSEHSFPLDHRQP
SSPPVQGLLILIRNITEVRSLQQAANQYSRLKELGEMAAHLAHEIRNPLGGIKGFATLLQQDLADRPELQQMAYHIIEGT
DSLNHFVSSILTYTRPFQARFEHVNLKTYLEEIGLLLQADVSWNASFSFNLNTHLPDLVLSIDPPLLKSAILNLLVNAMQ
AMPQGGKITVSVEKMQDEVVIIISDTGIGISKENLNKIFSPFFTTKETGTGLGLAEVQKVIQAHQGTIEVKSEVGNGTSF
TIKLPLKVVQ
>Mature_410_residues
MRMGQAFKQFSLETERLEFAYQSLQEQFKSVQKSLQESHTKHSGKLAELDFVTRYLETILNHISQGILFVDLNGIITTCN
TKTEEILKVQASRLLFHSFSDCFEDMAFGFSIQEVLQTKTCPRICFVTRALENDLKVELEIEPTFVSMSEHSFPLDHRQP
SSPPVQGLLILIRNITEVRSLQQAANQYSRLKELGEMAAHLAHEIRNPLGGIKGFATLLQQDLADRPELQQMAYHIIEGT
DSLNHFVSSILTYTRPFQARFEHVNLKTYLEEIGLLLQADVSWNASFSFNLNTHLPDLVLSIDPPLLKSAILNLLVNAMQ
AMPQGGKITVSVEKMQDEVVIIISDTGIGISKENLNKIFSPFFTTKETGTGLGLAEVQKVIQAHQGTIEVKSEVGNGTSF
TIKLPLKVVQ

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=361, Percent_Identity=32.9639889196676, Blast_Score=175, Evalue=5e-45,
Organism=Escherichia coli, GI1790436, Length=231, Percent_Identity=37.6623376623377, Blast_Score=151, Evalue=7e-38,
Organism=Escherichia coli, GI1790300, Length=362, Percent_Identity=27.9005524861878, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1786600, Length=267, Percent_Identity=23.9700374531835, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI48994928, Length=253, Percent_Identity=30.4347826086957, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI145693157, Length=260, Percent_Identity=30, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788713, Length=226, Percent_Identity=28.7610619469027, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1789149, Length=252, Percent_Identity=27.3809523809524, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081816, Length=226, Percent_Identity=30.5309734513274, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786783, Length=220, Percent_Identity=28.1818181818182, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790346, Length=226, Percent_Identity=27.4336283185841, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790861, Length=247, Percent_Identity=26.7206477732794, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1789808, Length=248, Percent_Identity=26.6129032258064, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790567, Length=363, Percent_Identity=25.068870523416, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786912, Length=269, Percent_Identity=27.1375464684015, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788393, Length=227, Percent_Identity=27.3127753303965, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87082128, Length=227, Percent_Identity=25.5506607929515, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 46035; Mature: 46035

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMGQAFKQFSLETERLEFAYQSLQEQFKSVQKSLQESHTKHSGKLAELDFVTRYLETIL
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
NHISQGILFVDLNGIITTCNTKTEEILKVQASRLLFHSFSDCFEDMAFGFSIQEVLQTKT
HHHHCCEEEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCC
CPRICFVTRALENDLKVELEIEPTFVSMSEHSFPLDHRQPSSPPVQGLLILIRNITEVRS
CCHHHHHHHHHCCCCEEEEEECCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LQQAANQYSRLKELGEMAAHLAHEIRNPLGGIKGFATLLQQDLADRPELQQMAYHIIEGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
DSLNHFVSSILTYTRPFQARFEHVNLKTYLEEIGLLLQADVSWNASFSFNLNTHLPDLVL
HHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHCCEEEECCCCCCEEEEEECCCCCCCEE
SIDPPLLKSAILNLLVNAMQAMPQGGKITVSVEKMQDEVVIIISDTGIGISKENLNKIFS
ECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHH
PFFTTKETGTGLGLAEVQKVIQAHQGTIEVKSEVGNGTSFTIKLPLKVVQ
HHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCEECC
>Mature Secondary Structure
MRMGQAFKQFSLETERLEFAYQSLQEQFKSVQKSLQESHTKHSGKLAELDFVTRYLETIL
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
NHISQGILFVDLNGIITTCNTKTEEILKVQASRLLFHSFSDCFEDMAFGFSIQEVLQTKT
HHHHCCEEEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCC
CPRICFVTRALENDLKVELEIEPTFVSMSEHSFPLDHRQPSSPPVQGLLILIRNITEVRS
CCHHHHHHHHHCCCCEEEEEECCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LQQAANQYSRLKELGEMAAHLAHEIRNPLGGIKGFATLLQQDLADRPELQQMAYHIIEGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
DSLNHFVSSILTYTRPFQARFEHVNLKTYLEEIGLLLQADVSWNASFSFNLNTHLPDLVL
HHHHHHHHHHHHHCCCHHHHHHHCHHHHHHHHHCCEEEECCCCCCEEEEEECCCCCCCEE
SIDPPLLKSAILNLLVNAMQAMPQGGKITVSVEKMQDEVVIIISDTGIGISKENLNKIFS
ECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHH
PFFTTKETGTGLGLAEVQKVIQAHQGTIEVKSEVGNGTSFTIKLPLKVVQ
HHHCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCEEEEEECCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]