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The map label for this gene is murG

Identifier: 46446882

GI number: 46446882

Start: 1488899

End: 1490029

Strand: Reverse

Name: murG

Synonym: pc1248

Alternate gene names: 46446882

Gene position: 1490029-1488899 (Counterclockwise)

Preceding gene: 46446883

Following gene: 46446881

Centisome position: 61.71

GC content: 34.39

Gene sequence:

>1131_bases
ATGTCTAAACGGTTTATGATTACAGCTGGTGGGACGGGGGGGCATATTTTTCCTGCTCAAGGATTAGCACAAGAACTCAT
CAAAAAAACCTATTCTTCCTCTATTTTGTTTGTTGCGGGCGGCCTTTCAACAAATAAATATTTTGATCGCTCCATTTTCC
CTTTTCAAGAAGTTTCTGCAAGTCCACTCTTTTCTAAAAATCCTTTTAAATTATTAAAAGGTGTTTTTAATCTTTTAAGA
GGCGTTTGGCAAAGTATTCGAATTATTAGAAAATTTAAACCAGATGTTGTTGTTGGATTTGGAAGTTACTATACAGTGCC
TCCTTTACTTGCAGCAAAAATTCTCCGTATTCCAATTGTTTTGCATGAAGCAAATAGTATTCCAGGAAAAGCTAACAAAT
GGCTTGCTTCAATGGCTTGGCGAGTAGGTATTCATTTTCCTTTTACAGCTACTTTGTTGAAAGGAAATACGATAGAAGTA
GGGATGCCTTTAAGAGAAGGGTATCAGCTTGATCAAATTGATAAAATAGAGGCATTATCTTATTTTGGATTAAGTAAAAA
TAACTCTACACTTTTAGTTTTCGGTGGATCTCAGGGAGCTTTAGCCATTAACAGATTGATGAGAAATTTAGCCAATACAT
GGAAGAATACACCTATTCAAATCATTCATATTACAGGAAGTATACAAGAAGCAGATGAACTTAAAATTTTTTATGCTAAT
TACCAAGTAAAAGCCTCTGTCAAAGCATTTGAAAAAAATATGCATTTAGCATGGCGTGCAGCAGAAGTATTTATAAGTCG
TTCAGGAGCTTCTACAATTGCTGAAGCAATGGAATTTGAAGTGCCAGGGATTTTAATTCCTTATCCTCACGCAACAGATC
ATCATCAAGACAAAAATGCTGATTTTTTTGTTGATATTGTTAAGGGTGGAATAAAAATTGTTGAAGAGAAAGCTAAACCA
GAAATTGTTCTTAAATCTATTCAACTGTTAATTGACCCTATAGCATTAGATAAAAGGAAAAGCGCTATCCATTCTTATAA
ATGTAGGCCAGATCGTACAACGCTTTGCGAGCTTGTTTTAGACACAAGCGAATTAAAAAGTTTACATAAAGCACCACAGA
AAAGGAAATAA

Upstream 100 bases:

>100_bases
GATTAAATCTTCCTTTTTTTAGCCAAGGTGGGACTTCATTAATGGCTAACATCGCAGGTCTCGGACTGTTATTAAATATT
GCTCATCAGAGGAGTCAAGT

Downstream 100 bases:

>100_bases
CCATGAGAGGGCATTATCATTTCATTGGAATCGGTGGAATAGGAATGAGCGGGCTTGCGCGAATTCTACTTCAACAAAAT
CTGAGTGTGTCAGGTAGTGA

Product: putative UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase MurG

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MSKRFMITAGGTGGHIFPAQGLAQELIKKTYSSSILFVAGGLSTNKYFDRSIFPFQEVSASPLFSKNPFKLLKGVFNLLR
GVWQSIRIIRKFKPDVVVGFGSYYTVPPLLAAKILRIPIVLHEANSIPGKANKWLASMAWRVGIHFPFTATLLKGNTIEV
GMPLREGYQLDQIDKIEALSYFGLSKNNSTLLVFGGSQGALAINRLMRNLANTWKNTPIQIIHITGSIQEADELKIFYAN
YQVKASVKAFEKNMHLAWRAAEVFISRSGASTIAEAMEFEVPGILIPYPHATDHHQDKNADFFVDIVKGGIKIVEEKAKP
EIVLKSIQLLIDPIALDKRKSAIHSYKCRPDRTTLCELVLDTSELKSLHKAPQKRK

Sequences:

>Translated_376_residues
MSKRFMITAGGTGGHIFPAQGLAQELIKKTYSSSILFVAGGLSTNKYFDRSIFPFQEVSASPLFSKNPFKLLKGVFNLLR
GVWQSIRIIRKFKPDVVVGFGSYYTVPPLLAAKILRIPIVLHEANSIPGKANKWLASMAWRVGIHFPFTATLLKGNTIEV
GMPLREGYQLDQIDKIEALSYFGLSKNNSTLLVFGGSQGALAINRLMRNLANTWKNTPIQIIHITGSIQEADELKIFYAN
YQVKASVKAFEKNMHLAWRAAEVFISRSGASTIAEAMEFEVPGILIPYPHATDHHQDKNADFFVDIVKGGIKIVEEKAKP
EIVLKSIQLLIDPIALDKRKSAIHSYKCRPDRTTLCELVLDTSELKSLHKAPQKRK
>Mature_375_residues
SKRFMITAGGTGGHIFPAQGLAQELIKKTYSSSILFVAGGLSTNKYFDRSIFPFQEVSASPLFSKNPFKLLKGVFNLLRG
VWQSIRIIRKFKPDVVVGFGSYYTVPPLLAAKILRIPIVLHEANSIPGKANKWLASMAWRVGIHFPFTATLLKGNTIEVG
MPLREGYQLDQIDKIEALSYFGLSKNNSTLLVFGGSQGALAINRLMRNLANTWKNTPIQIIHITGSIQEADELKIFYANY
QVKASVKAFEKNMHLAWRAAEVFISRSGASTIAEAMEFEVPGILIPYPHATDHHQDKNADFFVDIVKGGIKIVEEKAKPE
IVLKSIQLLIDPIALDKRKSAIHSYKCRPDRTTLCELVLDTSELKSLHKAPQKRK

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=335, Percent_Identity=30.4477611940298, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_PARUW (Q6MBS7)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_008247.1
- ProteinModelPortal:   Q6MBS7
- SMR:   Q6MBS7
- STRING:   Q6MBS7
- GeneID:   2780521
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc1248
- NMPDR:   fig|264201.1.peg.1248
- eggNOG:   COG0707
- OMA:   PHGNGEQ
- ProtClustDB:   CLSK2762358
- BioCyc:   CPRO264201:PC1248-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 41940; Mature: 41808

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRFMITAGGTGGHIFPAQGLAQELIKKTYSSSILFVAGGLSTNKYFDRSIFPFQEVSA
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHCCC
SPLFSKNPFKLLKGVFNLLRGVWQSIRIIRKFKPDVVVGFGSYYTVPPLLAAKILRIPIV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHEEE
LHEANSIPGKANKWLASMAWRVGIHFPFTATLLKGNTIEVGMPLREGYQLDQIDKIEALS
EEECCCCCCCHHHHHHHHHHHHEECCCEEEEEEECCEEEECCCHHCCCCCCCCHHHHHHH
YFGLSKNNSTLLVFGGSQGALAINRLMRNLANTWKNTPIQIIHITGSIQEADELKIFYAN
HCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEC
YQVKASVKAFEKNMHLAWRAAEVFISRSGASTIAEAMEFEVPGILIPYPHATDHHQDKNA
EEEEEHHHHHHCCCHHEEEEEEHEEECCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCC
DFFVDIVKGGIKIVEEKAKPEIVLKSIQLLIDPIALDKRKSAIHSYKCRPDRTTLCELVL
CEEEEEHHCCHHEEHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCHHHHHHHHH
DTSELKSLHKAPQKRK
CHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SKRFMITAGGTGGHIFPAQGLAQELIKKTYSSSILFVAGGLSTNKYFDRSIFPFQEVSA
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHCCC
SPLFSKNPFKLLKGVFNLLRGVWQSIRIIRKFKPDVVVGFGSYYTVPPLLAAKILRIPIV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHEEE
LHEANSIPGKANKWLASMAWRVGIHFPFTATLLKGNTIEVGMPLREGYQLDQIDKIEALS
EEECCCCCCCHHHHHHHHHHHHEECCCEEEEEEECCEEEECCCHHCCCCCCCCHHHHHHH
YFGLSKNNSTLLVFGGSQGALAINRLMRNLANTWKNTPIQIIHITGSIQEADELKIFYAN
HCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCEEEEEEC
YQVKASVKAFEKNMHLAWRAAEVFISRSGASTIAEAMEFEVPGILIPYPHATDHHQDKNA
EEEEEHHHHHHCCCHHEEEEEEHEEECCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCC
DFFVDIVKGGIKIVEEKAKPEIVLKSIQLLIDPIALDKRKSAIHSYKCRPDRTTLCELVL
CEEEEEHHCCHHEEHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCCHHHHHHHHH
DTSELKSLHKAPQKRK
CHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA