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The map label for this gene is xerD [H]

Identifier: 46446417

GI number: 46446417

Start: 965289

End: 966164

Strand: Direct

Name: xerD [H]

Synonym: pc0783

Alternate gene names: 46446417

Gene position: 965289-966164 (Clockwise)

Preceding gene: 46446416

Following gene: 46446421

Centisome position: 39.98

GC content: 35.05

Gene sequence:

>876_bases
ATGATTAGAGACTTAGAAGATTTTTTTATTTATTTAGCTTCAGAAAAAGGATTAGCTCAAAATACTTTAGAGGCTTATCG
AAGAGACCTTTTCTCTTTTGCAACCTTTTTGAAACAACGTTCAGTAAATAATTGGTCACAGATTCATTTGCAAGCTATAA
TTGATTATTTAGCTTTAAAACAACAACAACATTACGCCTCAGCTTCTATTTGTCGAGCTCTTATCGCCATTAAAGTTTTA
TTTCGCTTTTTAAAACGAGAAGGAATGATTACGACAAATATTCTTCTTCTGATGGAAACCCCTAAACTTTGGCAATTAAT
TCCAGATGTTCTTTCTTTAGAAGAAATAGATCGTATATTAGCCATACCTAACATTCAAACATGGAGAGGAGCACGAGATA
AAGCAATTTTAGAAACTTTATATGCTTGTGGATTACGAGTATCAGAACTTTGCCAATTGAAAATTTATGATGTGGACGAT
ACTTTTGTGCGAGTTTTAGGAAAAGGTGGAAAAGAAAGAATTGTTCCCATCGGGCAACAGGCAATTGCAGCCATCGATGG
TTATTTGTCTTTTAGAGAAGGGGGAGAAAATTCCAGAAATGAATTCCTTTTTATCACGAAAAAAAGTAAACCGCTTACTC
GTGCTCTTGTTTGGAAACTTGTCAAATTTTATGCCCGTCAAGCATCTATCTTCAAATCCATTTCTCCTCATACTTTTCGG
CATACGTTTGCGACTCATTTATTAGATCATGGGGCAGACTTAAGGGTTATTCAAGATATGCTTGGACACGCAAGCATCAA
TAGCACAGATCGATATACTCATGTTAGTCAAATACGCTTACAACAAGCTTTTCAAGCTTTTCATCCGAGAAATTGA

Upstream 100 bases:

>100_bases
CAATTAAAATTTTCCCTCTTACCACTTTAGAAACAGAAAAAGTACAAAAAAAATTAGCCGAAAAGTTAGGTGATGGCCAA
AAAATTAAGTCTCAACACTT

Downstream 100 bases:

>100_bases
AGAAATTTAAATTTGTTGTTAAGGTACAACTGCATTCGCTGAATTAGGTTGTTGACGTTGCTTGCAGCGATGGAAAAGAT
ATGTTCCACATTTCGCTGAA

Product: XerD protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MIRDLEDFFIYLASEKGLAQNTLEAYRRDLFSFATFLKQRSVNNWSQIHLQAIIDYLALKQQQHYASASICRALIAIKVL
FRFLKREGMITTNILLLMETPKLWQLIPDVLSLEEIDRILAIPNIQTWRGARDKAILETLYACGLRVSELCQLKIYDVDD
TFVRVLGKGGKERIVPIGQQAIAAIDGYLSFREGGENSRNEFLFITKKSKPLTRALVWKLVKFYARQASIFKSISPHTFR
HTFATHLLDHGADLRVIQDMLGHASINSTDRYTHVSQIRLQQAFQAFHPRN

Sequences:

>Translated_291_residues
MIRDLEDFFIYLASEKGLAQNTLEAYRRDLFSFATFLKQRSVNNWSQIHLQAIIDYLALKQQQHYASASICRALIAIKVL
FRFLKREGMITTNILLLMETPKLWQLIPDVLSLEEIDRILAIPNIQTWRGARDKAILETLYACGLRVSELCQLKIYDVDD
TFVRVLGKGGKERIVPIGQQAIAAIDGYLSFREGGENSRNEFLFITKKSKPLTRALVWKLVKFYARQASIFKSISPHTFR
HTFATHLLDHGADLRVIQDMLGHASINSTDRYTHVSQIRLQQAFQAFHPRN
>Mature_291_residues
MIRDLEDFFIYLASEKGLAQNTLEAYRRDLFSFATFLKQRSVNNWSQIHLQAIIDYLALKQQQHYASASICRALIAIKVL
FRFLKREGMITTNILLLMETPKLWQLIPDVLSLEEIDRILAIPNIQTWRGARDKAILETLYACGLRVSELCQLKIYDVDD
TFVRVLGKGGKERIVPIGQQAIAAIDGYLSFREGGENSRNEFLFITKKSKPLTRALVWKLVKFYARQASIFKSISPHTFR
HTFATHLLDHGADLRVIQDMLGHASINSTDRYTHVSQIRLQQAFQAFHPRN

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=293, Percent_Identity=41.9795221843003, Blast_Score=201, Evalue=6e-53,
Organism=Escherichia coli, GI1790244, Length=291, Percent_Identity=31.9587628865979, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI1790767, Length=169, Percent_Identity=29.585798816568, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790768, Length=155, Percent_Identity=29.6774193548387, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33541; Mature: 33541

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRDLEDFFIYLASEKGLAQNTLEAYRRDLFSFATFLKQRSVNNWSQIHLQAIIDYLALK
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QQQHYASASICRALIAIKVLFRFLKREGMITTNILLLMETPKLWQLIPDVLSLEEIDRIL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHEEEEEECCCHHHHHHHHHHHHHHHHHHH
AIPNIQTWRGARDKAILETLYACGLRVSELCQLKIYDVDDTFVRVLGKGGKERIVPIGQQ
HCCCCHHHCCCCHHHHHHHHHHCCCCHHHHHEEEEECCCHHHHHHHCCCCCCCCCCCHHH
AIAAIDGYLSFREGGENSRNEFLFITKKSKPLTRALVWKLVKFYARQASIFKSISPHTFR
HHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
HTFATHLLDHGADLRVIQDMLGHASINSTDRYTHVSQIRLQQAFQAFHPRN
HHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIRDLEDFFIYLASEKGLAQNTLEAYRRDLFSFATFLKQRSVNNWSQIHLQAIIDYLALK
CCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
QQQHYASASICRALIAIKVLFRFLKREGMITTNILLLMETPKLWQLIPDVLSLEEIDRIL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHEEEEEECCCHHHHHHHHHHHHHHHHHHH
AIPNIQTWRGARDKAILETLYACGLRVSELCQLKIYDVDDTFVRVLGKGGKERIVPIGQQ
HCCCCHHHCCCCHHHHHHHHHHCCCCHHHHHEEEEECCCHHHHHHHCCCCCCCCCCCHHH
AIAAIDGYLSFREGGENSRNEFLFITKKSKPLTRALVWKLVKFYARQASIFKSISPHTFR
HHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
HTFATHLLDHGADLRVIQDMLGHASINSTDRYTHVSQIRLQQAFQAFHPRN
HHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]