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The map label for this gene is infA [H]

Identifier: 46446228

GI number: 46446228

Start: 732478

End: 732747

Strand: Direct

Name: infA [H]

Synonym: pc0594

Alternate gene names: 46446228

Gene position: 732478-732747 (Clockwise)

Preceding gene: 46446225

Following gene: 46446229

Centisome position: 30.34

GC content: 36.67

Gene sequence:

>270_bases
ATGAAAAGAAGAACTTCTTCTTGTTTTTTAGGTTTTATTACAAGCGGCAACATGGCTAAAGAAGATACAATTAAGATTGA
AGGAAGCGTCGAAGAATTGCTCCCTAATATGCATTTTCGAGTTTCTCTTCAAAATGGATTAAATGTGATCGCACATCTTT
GTGGGAAAATGCGTATGAAAAACATACGTGTTCTAGTCGGAGATGTTGTTACTGTAGAGATGTCGCCTTATGACTTAAGC
AAGGCAAGAATTATTTTTCGACAGCGCTAG

Upstream 100 bases:

>100_bases
GATTGATCAAAAATAAATTTTCTTGATTTTTTGGCTTGACTTTTATCTATAAAATGCTAATTTATTAGTCACTATTTCGA
AGATTTGTCTTTTCAATTTT

Downstream 100 bases:

>100_bases
CGATAGATTAACACAAAGAGTGTTGATTTTTTTTAGCTGACTCTCTACGCTTATTAAATTTTTAATCATGGGTAGAAAGC
GCTTTTGCAAGATTAGCTTG

Product: translation initiation factor IF-1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 89; Mature: 89

Protein sequence:

>89_residues
MKRRTSSCFLGFITSGNMAKEDTIKIEGSVEELLPNMHFRVSLQNGLNVIAHLCGKMRMKNIRVLVGDVVTVEMSPYDLS
KARIIFRQR

Sequences:

>Translated_89_residues
MKRRTSSCFLGFITSGNMAKEDTIKIEGSVEELLPNMHFRVSLQNGLNVIAHLCGKMRMKNIRVLVGDVVTVEMSPYDLS
KARIIFRQR
>Mature_89_residues
MKRRTSSCFLGFITSGNMAKEDTIKIEGSVEELLPNMHFRVSLQNGLNVIAHLCGKMRMKNIRVLVGDVVTVEMSPYDLS
KARIIFRQR

Specific function: No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 [H]

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain [H]

Homologues:

Organism=Escherichia coli, GI1787110, Length=72, Percent_Identity=62.5, Blast_Score=97, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR022967
- InterPro:   IPR006196
- InterPro:   IPR004368 [H]

Pfam domain/function: PF01176 eIF-1a [H]

EC number: NA

Molecular weight: Translated: 10128; Mature: 10128

Theoretical pI: Translated: 10.56; Mature: 10.56

Prosite motif: PS50832 S1_IF1_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
6.7 %Met     (Translated Protein)
9.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
6.7 %Met     (Mature Protein)
9.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRRTSSCFLGFITSGNMAKEDTIKIEGSVEELLPNMHFRVSLQNGLNVIAHLCGKMRMK
CCCCCCCEEEEEEECCCCCCCCEEEEECCHHHHCCCCEEEEEECCCHHHHHHHHHHHCCC
NIRVLVGDVVTVEMSPYDLSKARIIFRQR
CEEEEECCEEEEEECCCCCCCEEEEEECC
>Mature Secondary Structure
MKRRTSSCFLGFITSGNMAKEDTIKIEGSVEELLPNMHFRVSLQNGLNVIAHLCGKMRMK
CCCCCCCEEEEEEECCCCCCCCEEEEECCHHHHCCCCEEEEEECCCHHHHHHHHHHHCCC
NIRVLVGDVVTVEMSPYDLSKARIIFRQR
CEEEEECCEEEEEECCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA