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The map label for this gene is pckI [C]

Identifier: 46446217

GI number: 46446217

Start: 718642

End: 718980

Strand: Direct

Name: pckI [C]

Synonym: pc0583

Alternate gene names: 46446217

Gene position: 718642-718980 (Clockwise)

Preceding gene: 46446216

Following gene: 46446218

Centisome position: 29.76

GC content: 37.46

Gene sequence:

>339_bases
TTGATGACGACAGTATTCGGAAAAATTATTAAAGGCGAGCTTTCAGCAGAAAAAGTTTTTGAAAATGAACGCATTATGGT
CATCAAAGATCTTTATCCAGTCGCTCCAGTCCACTTACTTATTATTCCCAAAAAAGAAATTCCGAATTTACAGTCTATCC
AACAAGAAGATCTTGAACTCGTGAGCGAAATCGTAGTCATTGCTCAGCAACTTGCCAAGCAATTTAATATTGAAGAAGGG
TATCGGTTGGTCACAAATAATGGAACGATGGCTGGGCAGGTTATTTTTCATTTGCATTTCCATTTAATTGGAGGACGTCA
ATTAGGAAGCTTGGGATAA

Upstream 100 bases:

>100_bases
GTTTTTTGCCATAAAGGGCGTTTTATATCGGTTTGGGAAACAAAAGAAGATGCATTGAAAGCTTTAGATTACACCTTAAA
GTATACTTAGGAGATTTTAA

Downstream 100 bases:

>100_bases
CTTTTTCAAAAATCTATCCATTTGGATGATTCCCGAATTATTTTAATTTGGGTTTAAATATAAAAAAGTTTAGAAACTAT
TATGATCTTACCTATTAACT

Product: putative protein kinase C inhibitor 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 112; Mature: 112

Protein sequence:

>112_residues
MMTTVFGKIIKGELSAEKVFENERIMVIKDLYPVAPVHLLIIPKKEIPNLQSIQQEDLELVSEIVVIAQQLAKQFNIEEG
YRLVTNNGTMAGQVIFHLHFHLIGGRQLGSLG

Sequences:

>Translated_112_residues
MMTTVFGKIIKGELSAEKVFENERIMVIKDLYPVAPVHLLIIPKKEIPNLQSIQQEDLELVSEIVVIAQQLAKQFNIEEG
YRLVTNNGTMAGQVIFHLHFHLIGGRQLGSLG
>Mature_112_residues
MMTTVFGKIIKGELSAEKVFENERIMVIKDLYPVAPVHLLIIPKKEIPNLQSIQQEDLELVSEIVVIAQQLAKQFNIEEG
YRLVTNNGTMAGQVIFHLHFHLIGGRQLGSLG

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI14211923, Length=105, Percent_Identity=41.9047619047619, Blast_Score=108, Evalue=9e-25,
Organism=Homo sapiens, GI4885413, Length=106, Percent_Identity=37.7358490566038, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1787346, Length=109, Percent_Identity=36.697247706422, Blast_Score=79, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17506713, Length=105, Percent_Identity=43.8095238095238, Blast_Score=107, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6320078, Length=108, Percent_Identity=36.1111111111111, Blast_Score=65, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28574010, Length=105, Percent_Identity=36.1904761904762, Blast_Score=100, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24581222, Length=105, Percent_Identity=36.1904761904762, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 12580; Mature: 12580

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00892 HIT_1 ; PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTTVFGKIIKGELSAEKVFENERIMVIKDLYPVAPVHLLIIPKKEIPNLQSIQQEDLEL
CCHHHHHHHHHCCCCHHHHHCCCCEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHH
VSEIVVIAQQLAKQFNIEEGYRLVTNNGTMAGQVIFHLHFHLIGGRQLGSLG
HHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MMTTVFGKIIKGELSAEKVFENERIMVIKDLYPVAPVHLLIIPKKEIPNLQSIQQEDLEL
CCHHHHHHHHHCCCCHHHHHCCCCEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHH
VSEIVVIAQQLAKQFNIEEGYRLVTNNGTMAGQVIFHLHFHLIGGRQLGSLG
HHHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]