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The map label for this gene is nuoN

Identifier: 46446206

GI number: 46446206

Start: 706056

End: 707498

Strand: Direct

Name: nuoN

Synonym: pc0572

Alternate gene names: 46446206

Gene position: 706056-707498 (Clockwise)

Preceding gene: 46446205

Following gene: 46446208

Centisome position: 29.24

GC content: 35.14

Gene sequence:

>1443_bases
ATGAATCCTACTTTGACATTAACCGATTTTATTTCTATCGGGCCATTATTAATTGTTTTAATGACCGCTTTAATCATTAT
CCTTATAGAAAGTTTCAGTGAGAACTGTTCCAAAAAATGGTCTTCTCTTATTTCTATTGGTGGACTCACACTATCCATTT
TCGCCGTATGGGGGGGAATTTCTTCTAATCATAGCTCATTGTTAAATCCTTGGATTCATTTTGATACTTTAGCACGATTT
TTTACTGTTTTTTTCTTAGTAATCGGAATCGGAGCCTCTCTTTTAGCAACTGCATTTTTTCAAAGATTCAAAGCATCGCA
TGGGGAATATTTTTTTCTTCTTCAATCGGCCGTTTTTGGATTGATTTTGATTGGAGCCGCTGCGGATCTTCTAACATTAT
TTTTAGGAATTGAAACACTTTCTATCTCATTATACGTTTTATGCGGGTATATGAAAAAATGGGAAATTTCTCATGAATCA
TCTTTTAAATATTTTTTGATGGGCTCGATTGTCGCTGGATTTCTCTTATATGGAATTGCTTTAGTTTATGGTGCAATTGG
GACGACACGATTAGATGTTTTACTTTCTTCTTATCAAACGATTTCTTTAACTACGGAAAAAGTTTTGTTTTTCAGTGGAA
TTGCCATGATAACTTTAGGACTGGCTTTTAAAGCGGCTCTTGTTCCTTTTCATACTTGGTCACCAGATGTTTATGCTGGG
GCTTCAAACCCGGTTACGGCATTTATGGCTGTAGGGACTAAGGTAGGGGTTTTTGCTGCTTTTGTGCGCTTATTTTTTGA
AGCCTTGCCACAATTTGATGCAGCTTGGAATCAGGTGATTGATACATTAGTTTACGCAACTCTTATTTATGCTAATTTTG
TCGCATTAAAACAAATACAATTACGTCGCTTTTTTGCCTATTCAAGCATTTCGCACGCAGGATTTTTAATGATTCCTGTT
GTTATAGGAAATCAAGAAGCCTTATCCGCTTTGACTTTTTATCTTGTGATTTATGCTATTGCAACGTTTGGATGTTTTGC
CGTTTTAGCTTATCTTGATCAAAATCAAGAAGGTGTTCATTTTTCAGATTTACATGGATTATTTAGTCGATCTCCTTGGC
TGGCAAGTCTTCTTTCTATTTGTTTATTAACCCTAGCAGGTATTCCTCCTACAGCGGGATTTTTGGCTAAATTTTATGTT
TTTAAAGTGGCCTTTCAAGCAGGTTATTATGGACTCGTTATTGTTGGGTTACTCACAACAATTCTTTCTTCGTATTATTA
CTTACGAATTATTGGAATATTGTTTTCAGAATCCAAAAATGATGAAAAACTCCCTTACTCTATGCCAGCGGCAATTGTGG
GAACCACCTCATTTATAGCTATTATTATTCTCTCTTTTTATCCAGCTCCCTTTTTAAAGGTTCTAAGTCATTTATCAAAC
TAA

Upstream 100 bases:

>100_bases
TCTTTTTAAACTTATGGATTGGCTTATATCCCATGGGAATTCTCAAATATTTAGACGCTGATCATTCCAAATCGCAAGTA
TTGACTCAGGAGATGATAAA

Downstream 100 bases:

>100_bases
CTTAACGTAACCATTTGCTTAAATTTATCAAAAAATACGGGATTATTAAAAAATATCTTTAAGTTTTCTTCCTTCTGTTA
GATGAGGAGAGGGTGGATGC

Product: putative NADH-ubiquinone oxidoreductase chain N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MNPTLTLTDFISIGPLLIVLMTALIIILIESFSENCSKKWSSLISIGGLTLSIFAVWGGISSNHSSLLNPWIHFDTLARF
FTVFFLVIGIGASLLATAFFQRFKASHGEYFFLLQSAVFGLILIGAAADLLTLFLGIETLSISLYVLCGYMKKWEISHES
SFKYFLMGSIVAGFLLYGIALVYGAIGTTRLDVLLSSYQTISLTTEKVLFFSGIAMITLGLAFKAALVPFHTWSPDVYAG
ASNPVTAFMAVGTKVGVFAAFVRLFFEALPQFDAAWNQVIDTLVYATLIYANFVALKQIQLRRFFAYSSISHAGFLMIPV
VIGNQEALSALTFYLVIYAIATFGCFAVLAYLDQNQEGVHFSDLHGLFSRSPWLASLLSICLLTLAGIPPTAGFLAKFYV
FKVAFQAGYYGLVIVGLLTTILSSYYYLRIIGILFSESKNDEKLPYSMPAAIVGTTSFIAIIILSFYPAPFLKVLSHLSN

Sequences:

>Translated_480_residues
MNPTLTLTDFISIGPLLIVLMTALIIILIESFSENCSKKWSSLISIGGLTLSIFAVWGGISSNHSSLLNPWIHFDTLARF
FTVFFLVIGIGASLLATAFFQRFKASHGEYFFLLQSAVFGLILIGAAADLLTLFLGIETLSISLYVLCGYMKKWEISHES
SFKYFLMGSIVAGFLLYGIALVYGAIGTTRLDVLLSSYQTISLTTEKVLFFSGIAMITLGLAFKAALVPFHTWSPDVYAG
ASNPVTAFMAVGTKVGVFAAFVRLFFEALPQFDAAWNQVIDTLVYATLIYANFVALKQIQLRRFFAYSSISHAGFLMIPV
VIGNQEALSALTFYLVIYAIATFGCFAVLAYLDQNQEGVHFSDLHGLFSRSPWLASLLSICLLTLAGIPPTAGFLAKFYV
FKVAFQAGYYGLVIVGLLTTILSSYYYLRIIGILFSESKNDEKLPYSMPAAIVGTTSFIAIIILSFYPAPFLKVLSHLSN
>Mature_480_residues
MNPTLTLTDFISIGPLLIVLMTALIIILIESFSENCSKKWSSLISIGGLTLSIFAVWGGISSNHSSLLNPWIHFDTLARF
FTVFFLVIGIGASLLATAFFQRFKASHGEYFFLLQSAVFGLILIGAAADLLTLFLGIETLSISLYVLCGYMKKWEISHES
SFKYFLMGSIVAGFLLYGIALVYGAIGTTRLDVLLSSYQTISLTTEKVLFFSGIAMITLGLAFKAALVPFHTWSPDVYAG
ASNPVTAFMAVGTKVGVFAAFVRLFFEALPQFDAAWNQVIDTLVYATLIYANFVALKQIQLRRFFAYSSISHAGFLMIPV
VIGNQEALSALTFYLVIYAIATFGCFAVLAYLDQNQEGVHFSDLHGLFSRSPWLASLLSICLLTLAGIPPTAGFLAKFYV
FKVAFQAGYYGLVIVGLLTTILSSYYYLRIIGILFSESKNDEKLPYSMPAAIVGTTSFIAIIILSFYPAPFLKVLSHLSN

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family

Homologues:

Organism=Escherichia coli, GI145693160, Length=482, Percent_Identity=30.9128630705394, Blast_Score=222, Evalue=3e-59,
Organism=Escherichia coli, GI1788831, Length=341, Percent_Identity=22.2873900293255, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788614, Length=399, Percent_Identity=23.3082706766917, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788613, Length=189, Percent_Identity=25.9259259259259, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788827, Length=451, Percent_Identity=21.7294900221729, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUON_PARUW (Q6MDQ3)

Other databases:

- EMBL:   BX908798
- RefSeq:   YP_007571.1
- STRING:   Q6MDQ3
- GeneID:   2781353
- GenomeReviews:   BX908798_GR
- KEGG:   pcu:pc0572
- NMPDR:   fig|264201.1.peg.572
- HOGENOM:   HBG747830
- OMA:   FESVSIM
- PhylomeDB:   Q6MDQ3
- BioCyc:   CPRO264201:PC0572-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00445
- InterPro:   IPR010096
- InterPro:   IPR001750
- TIGRFAMs:   TIGR01770

Pfam domain/function: PF00361 Oxidored_q1

EC number: =1.6.99.5

Molecular weight: Translated: 52627; Mature: 52627

Theoretical pI: Translated: 7.97; Mature: 7.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x403a0d10)-; HASH(0xc3c4078)-; HASH(0xcb88d34)-; HASH(0xcefb3a0)-; HASH(0xc353bd8)-; HASH(0xca6247c)-; HASH(0xbf8bb08)-; HASH(0x9519274)-; HASH(0xcef89dc)-; HASH(0xc78c930)-; HASH(0xce9c59c)-; HASH(0xbe61c90)-; HASH(0x94beb20)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPTLTLTDFISIGPLLIVLMTALIIILIESFSENCSKKWSSLISIGGLTLSIFAVWGGI
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
SSNHSSLLNPWIHFDTLARFFTVFFLVIGIGASLLATAFFQRFKASHGEYFFLLQSAVFG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LILIGAAADLLTLFLGIETLSISLYVLCGYMKKWEISHESSFKYFLMGSIVAGFLLYGIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
LVYGAIGTTRLDVLLSSYQTISLTTEKVLFFSGIAMITLGLAFKAALVPFHTWSPDVYAG
HHHHCCCHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
ASNPVTAFMAVGTKVGVFAAFVRLFFEALPQFDAAWNQVIDTLVYATLIYANFVALKQIQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRRFFAYSSISHAGFLMIPVVIGNQEALSALTFYLVIYAIATFGCFAVLAYLDQNQEGVH
HHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
FSDLHGLFSRSPWLASLLSICLLTLAGIPPTAGFLAKFYVFKVAFQAGYYGLVIVGLLTT
HHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ILSSYYYLRIIGILFSESKNDEKLPYSMPAAIVGTTSFIAIIILSFYPAPFLKVLSHLSN
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCH
>Mature Secondary Structure
MNPTLTLTDFISIGPLLIVLMTALIIILIESFSENCSKKWSSLISIGGLTLSIFAVWGGI
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
SSNHSSLLNPWIHFDTLARFFTVFFLVIGIGASLLATAFFQRFKASHGEYFFLLQSAVFG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LILIGAAADLLTLFLGIETLSISLYVLCGYMKKWEISHESSFKYFLMGSIVAGFLLYGIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
LVYGAIGTTRLDVLLSSYQTISLTTEKVLFFSGIAMITLGLAFKAALVPFHTWSPDVYAG
HHHHCCCHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
ASNPVTAFMAVGTKVGVFAAFVRLFFEALPQFDAAWNQVIDTLVYATLIYANFVALKQIQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRRFFAYSSISHAGFLMIPVVIGNQEALSALTFYLVIYAIATFGCFAVLAYLDQNQEGVH
HHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
FSDLHGLFSRSPWLASLLSICLLTLAGIPPTAGFLAKFYVFKVAFQAGYYGLVIVGLLTT
HHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
ILSSYYYLRIIGILFSESKNDEKLPYSMPAAIVGTTSFIAIIILSFYPAPFLKVLSHLSN
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA