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The map label for this gene is hprK [H]

Identifier: 46446108

GI number: 46446108

Start: 609787

End: 610734

Strand: Direct

Name: hprK [H]

Synonym: pc0474

Alternate gene names: 46446108

Gene position: 609787-610734 (Clockwise)

Preceding gene: 46446107

Following gene: 46446109

Centisome position: 25.26

GC content: 34.92

Gene sequence:

>948_bases
ATGTATTTAGTTAAAAAATTATATGAAGAACACGCAAAAAAACTTGGACTTGAGTTGACTGCGGGTAAAAATGGGATAAA
TAGACGCATTAAAGTTCCAGAGGCTCAAAGACCTGGATTGAGCTTAAGCGGATATCTTAAGTATTATGCTGAAAAGCGAA
TTCTTATTTTCGGTAAAGTAGAGATCGAGTATATCCGAGATTTAGATTCTCAAATTCGCATAGAGCGTCTAGAAGCAATT
GTTAAGCAAAATACTCCGGCAGTGATAGTGAGTAGGCGTTATCGTCCCCCAAAAGAGCTGAGGGCTATTTGTGAAAAATT
AAATATTCCTCTTTTTCGTACAAATTTATCTACCATGAATTTGATGAGCCAATTAACACTACTTTTAACAGAAGAATTTG
CTCCTAGTGTTAGTTGTCATGGGTCTCTTGTTGAGGTATTTGGAGTGGGTGTTTTAATTCAAGGGGATTCTTCTGTAGGT
AAAAGCGAGGCTGCTCTTGGATTAATTGAAAGAGGGCATCGTCTTATTTCAGATGATATCGTGAAAGTAAAAAAGAAAGA
AGGAACATATTTAGAAGGTTCTGGAGTTGCTTTAACGCGCCATCATATGGAAATTAGAGGAATTGGGATTATTAATGTTG
CTAATCTTTATGGAGCAGTTTGCGTAAGAGATCAAAAAAGTATTGATATTGTTGTCCGATTAGAGGCATGGCATGATGAA
CATTTTTATGATCGGATTGGTTTAGACGAAAAATTTACAAAAATTCTAGATGTAAAACTTCCGTATTTAACTTTACCTGT
TAAGCCAGGAAGAGATGTTGTTTTATTACTAGAAACCATGGCTTTAAATCATCGCTTGAAGAATATGGGTTATAACTCGG
CTCAAGAATTTACGACAAAAGTATTAGAATTAACGACATCTAAAGTCAGAAAGAAAATTTTACCTTAA

Upstream 100 bases:

>100_bases
TAGATTGTGCGAAGCTGGATGATTGCGTAGAAACAATGGCTTTTGCAACGTTTACTGAGTGGTTAATGTTCTATCTTGAA
AAAATCGACTAATTTGGCTC

Downstream 100 bases:

>100_bases
GGATGTAAATACATTCTAAAAACCAAGGAAAAATTGTGAAACTCGTTTGTAAAGTACAAGTAAAAAATCGCATGGGTCTT
CATACGCGACCAGCAACCAC

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MYLVKKLYEEHAKKLGLELTAGKNGINRRIKVPEAQRPGLSLSGYLKYYAEKRILIFGKVEIEYIRDLDSQIRIERLEAI
VKQNTPAVIVSRRYRPPKELRAICEKLNIPLFRTNLSTMNLMSQLTLLLTEEFAPSVSCHGSLVEVFGVGVLIQGDSSVG
KSEAALGLIERGHRLISDDIVKVKKKEGTYLEGSGVALTRHHMEIRGIGIINVANLYGAVCVRDQKSIDIVVRLEAWHDE
HFYDRIGLDEKFTKILDVKLPYLTLPVKPGRDVVLLLETMALNHRLKNMGYNSAQEFTTKVLELTTSKVRKKILP

Sequences:

>Translated_315_residues
MYLVKKLYEEHAKKLGLELTAGKNGINRRIKVPEAQRPGLSLSGYLKYYAEKRILIFGKVEIEYIRDLDSQIRIERLEAI
VKQNTPAVIVSRRYRPPKELRAICEKLNIPLFRTNLSTMNLMSQLTLLLTEEFAPSVSCHGSLVEVFGVGVLIQGDSSVG
KSEAALGLIERGHRLISDDIVKVKKKEGTYLEGSGVALTRHHMEIRGIGIINVANLYGAVCVRDQKSIDIVVRLEAWHDE
HFYDRIGLDEKFTKILDVKLPYLTLPVKPGRDVVLLLETMALNHRLKNMGYNSAQEFTTKVLELTTSKVRKKILP
>Mature_315_residues
MYLVKKLYEEHAKKLGLELTAGKNGINRRIKVPEAQRPGLSLSGYLKYYAEKRILIFGKVEIEYIRDLDSQIRIERLEAI
VKQNTPAVIVSRRYRPPKELRAICEKLNIPLFRTNLSTMNLMSQLTLLLTEEFAPSVSCHGSLVEVFGVGVLIQGDSSVG
KSEAALGLIERGHRLISDDIVKVKKKEGTYLEGSGVALTRHHMEIRGIGIINVANLYGAVCVRDQKSIDIVVRLEAWHDE
HFYDRIGLDEKFTKILDVKLPYLTLPVKPGRDVVLLLETMALNHRLKNMGYNSAQEFTTKVLELTTSKVRKKILP

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126 [H]

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N [H]

EC number: NA

Molecular weight: Translated: 35661; Mature: 35661

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLVKKLYEEHAKKLGLELTAGKNGINRRIKVPEAQRPGLSLSGYLKYYAEKRILIFGKV
CHHHHHHHHHHHHHCCCEEECCCCCCCCEEECCCCCCCCCCHHHHHHHHCCCEEEEEEEE
EIEYIRDLDSQIRIERLEAIVKQNTPAVIVSRRYRPPKELRAICEKLNIPLFRTNLSTMN
EHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCEEECCHHHHH
LMSQLTLLLTEEFAPSVSCHGSLVEVFGVGVLIQGDSSVGKSEAALGLIERGHRLISDDI
HHHHHHHHHHHHCCCCCCCCCHHHHHHCCEEEEECCCCCCCHHHHHHHHHHCCHHHHHHH
VKVKKKEGTYLEGSGVALTRHHMEIRGIGIINVANLYGAVCVRDQKSIDIVVRLEAWHDE
HHEECCCCCEECCCCEEEEEECEEEEEEEEEEHHHHHHEEEEECCCCEEEEEEEEECCCC
HFYDRIGLDEKFTKILDVKLPYLTLPVKPGRDVVLLLETMALNHRLKNMGYNSAQEFTTK
HHHHHCCCCHHHHHHHHEECCEEEECCCCCCCEEEEHHHHHHHHHHHHCCCCCHHHHHHH
VLELTTSKVRKKILP
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MYLVKKLYEEHAKKLGLELTAGKNGINRRIKVPEAQRPGLSLSGYLKYYAEKRILIFGKV
CHHHHHHHHHHHHHCCCEEECCCCCCCCEEECCCCCCCCCCHHHHHHHHCCCEEEEEEEE
EIEYIRDLDSQIRIERLEAIVKQNTPAVIVSRRYRPPKELRAICEKLNIPLFRTNLSTMN
EHHHHHCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCEEECCHHHHH
LMSQLTLLLTEEFAPSVSCHGSLVEVFGVGVLIQGDSSVGKSEAALGLIERGHRLISDDI
HHHHHHHHHHHHCCCCCCCCCHHHHHHCCEEEEECCCCCCCHHHHHHHHHHCCHHHHHHH
VKVKKKEGTYLEGSGVALTRHHMEIRGIGIINVANLYGAVCVRDQKSIDIVVRLEAWHDE
HHEECCCCCEECCCCEEEEEECEEEEEEEEEEHHHHHHEEEEECCCCEEEEEEEEECCCC
HFYDRIGLDEKFTKILDVKLPYLTLPVKPGRDVVLLLETMALNHRLKNMGYNSAQEFTTK
HHHHHCCCCHHHHHHHHEECCEEEECCCCCCCEEEEHHHHHHHHHHHHCCCCCHHHHHHH
VLELTTSKVRKKILP
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA