Definition Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence.
Accession NC_005823
Length 4,277,185

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The map label for this gene is yddE [C]

Identifier: 45659082

GI number: 45659082

Start: 3997780

End: 3998604

Strand: Reverse

Name: yddE [C]

Synonym: LIC13261

Alternate gene names: 45659082

Gene position: 3998604-3997780 (Counterclockwise)

Preceding gene: 45659083

Following gene: 45659079

Centisome position: 93.49

GC content: 37.21

Gene sequence:

>825_bases
TTGAAATCAATCTTACAATGGGAGTGTTCCAAAGCCATCTTTATGAAACTTAGAATGTTACAAATTGACTCGTTTGCGGA
AAAAGTTTTTCAAGGAAATCCAGCCGCCGTTTGTCCATTACAAGAATGGATCTCCGACGAATGGATGCAAAAGATTGCGT
CGGAAAACAATCTGAGTGAAACCGCCTTTTTTGTGCTTGAAGGAGAATCGTATCGGATTCGGTGGTTTACGCCTTTACGC
GAAGTGGATCTTTGTGGTCATGCTACTTTGGCTGCAGCCTATCATCTTTTTCGAGAAGGTGAAGTGATAGGAGACAAGTT
AAATTTTCAATCCTTATCTGGGGAATTAAACGTATTTAAAAAAGAAAATATTCTCTATTTGGATTTTCCTTCTCGGAAAC
CAGAAAAAGTAGAAACTCCAAAAGAGATTTTGAATTCATTTTCAATTTCTCCTAAAGAAGTTTTTAAATCTAGAGATTAT
ATGCTCTTGTATGAAAATGAAAACCAACTTAAAAAGTTAGAATATTCTGTGGAGGGAGTTAGAGAACTGAATACATTAGG
CATCATTGCTACTTGTGTGGGAAACGATTCTTACGATTTTTTGTCTCGGTTTTTTGCTCCGTCTGTGGGTTTGTATGAAG
ATCCGGTAACCGGTTCTGCACATTGTACTCTCATTCCATTTTGGTCTGAGCGTTTGGGTAAAAAAATAATGAAAGCATAT
CAAACTTCTGCTCGAGGTGGAAAACTTTTTTGCGAAGATTTAGGAGAAAGAGTTCGTATTGGAGGAACTTGTGTTCCCTA
TTTGGATGGGTGGATTGAAATATAA

Upstream 100 bases:

>100_bases
GTAAATTACCGAAGGAAACGGTTTTTATGGGAGCCATTACTTCACGTTTTTTGTTAAAAACTTGCAAAATGGATTTCCAT
TAAATTTTGGGTAATTCTTT

Downstream 100 bases:

>100_bases
AGGAATTCTTAAGTAATTTCGTTTTTAAGATGTTTATGTTTGAAAAGAAGTTCTTTGATAAGGTTTTTTTCTGATCTTCC
CAAAATTTCTTTTTCTTCAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MKSILQWECSKAIFMKLRMLQIDSFAEKVFQGNPAAVCPLQEWISDEWMQKIASENNLSETAFFVLEGESYRIRWFTPLR
EVDLCGHATLAAAYHLFREGEVIGDKLNFQSLSGELNVFKKENILYLDFPSRKPEKVETPKEILNSFSISPKEVFKSRDY
MLLYENENQLKKLEYSVEGVRELNTLGIIATCVGNDSYDFLSRFFAPSVGLYEDPVTGSAHCTLIPFWSERLGKKIMKAY
QTSARGGKLFCEDLGERVRIGGTCVPYLDGWIEI

Sequences:

>Translated_274_residues
MKSILQWECSKAIFMKLRMLQIDSFAEKVFQGNPAAVCPLQEWISDEWMQKIASENNLSETAFFVLEGESYRIRWFTPLR
EVDLCGHATLAAAYHLFREGEVIGDKLNFQSLSGELNVFKKENILYLDFPSRKPEKVETPKEILNSFSISPKEVFKSRDY
MLLYENENQLKKLEYSVEGVRELNTLGIIATCVGNDSYDFLSRFFAPSVGLYEDPVTGSAHCTLIPFWSERLGKKIMKAY
QTSARGGKLFCEDLGERVRIGGTCVPYLDGWIEI
>Mature_274_residues
MKSILQWECSKAIFMKLRMLQIDSFAEKVFQGNPAAVCPLQEWISDEWMQKIASENNLSETAFFVLEGESYRIRWFTPLR
EVDLCGHATLAAAYHLFREGEVIGDKLNFQSLSGELNVFKKENILYLDFPSRKPEKVETPKEILNSFSISPKEVFKSRDY
MLLYENENQLKKLEYSVEGVRELNTLGIIATCVGNDSYDFLSRFFAPSVGLYEDPVTGSAHCTLIPFWSERLGKKIMKAY
QTSARGGKLFCEDLGERVRIGGTCVPYLDGWIEI

Specific function: Unknown

COG id: COG0384

COG function: function code R; Predicted epimerase, PhzC/PhzF homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phzF family [H]

Homologues:

Organism=Homo sapiens, GI62177133, Length=286, Percent_Identity=37.0629370629371, Blast_Score=162, Evalue=3e-40,
Organism=Homo sapiens, GI74316009, Length=252, Percent_Identity=36.9047619047619, Blast_Score=147, Evalue=1e-35,
Organism=Escherichia coli, GI1787737, Length=291, Percent_Identity=29.2096219931272, Blast_Score=88, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17542160, Length=308, Percent_Identity=33.1168831168831, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17542154, Length=308, Percent_Identity=33.1168831168831, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17542158, Length=306, Percent_Identity=32.6797385620915, Blast_Score=123, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI17542152, Length=306, Percent_Identity=32.6797385620915, Blast_Score=123, Evalue=9e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003719 [H]

Pfam domain/function: PF02567 PhzC-PhzF [H]

EC number: NA

Molecular weight: Translated: 31381; Mature: 31381

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSILQWECSKAIFMKLRMLQIDSFAEKVFQGNPAAVCPLQEWISDEWMQKIASENNLSE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHCCCCCCC
TAFFVLEGESYRIRWFTPLREVDLCGHATLAAAYHLFREGEVIGDKLNFQSLSGELNVFK
EEEEEEECCCEEEEEECCHHHHHHCCHHHHHHHHHHHHCCCEECCCCCHHHCCCCEEEEE
KENILYLDFPSRKPEKVETPKEILNSFSISPKEVFKSRDYMLLYENENQLKKLEYSVEGV
ECCEEEEECCCCCCCCCCCHHHHHHHCCCCHHHHHCCCCEEEEECCCCHHHHHHHHHHHH
RELNTLGIIATCVGNDSYDFLSRFFAPSVGLYEDPVTGSAHCTLIPFWSERLGKKIMKAY
HHHHHHEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHH
QTSARGGKLFCEDLGERVRIGGTCVPYLDGWIEI
HHCCCCCEEHHHHHCCEEECCCEECCCCCCEECC
>Mature Secondary Structure
MKSILQWECSKAIFMKLRMLQIDSFAEKVFQGNPAAVCPLQEWISDEWMQKIASENNLSE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHCCCCCCC
TAFFVLEGESYRIRWFTPLREVDLCGHATLAAAYHLFREGEVIGDKLNFQSLSGELNVFK
EEEEEEECCCEEEEEECCHHHHHHCCHHHHHHHHHHHHCCCEECCCCCHHHCCCCEEEEE
KENILYLDFPSRKPEKVETPKEILNSFSISPKEVFKSRDYMLLYENENQLKKLEYSVEGV
ECCEEEEECCCCCCCCCCCHHHHHHHCCCCHHHHHCCCCEEEEECCCCHHHHHHHHHHHH
RELNTLGIIATCVGNDSYDFLSRFFAPSVGLYEDPVTGSAHCTLIPFWSERLGKKIMKAY
HHHHHHEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHH
QTSARGGKLFCEDLGERVRIGGTCVPYLDGWIEI
HHCCCCCEEHHHHHCCEEECCCEECCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]