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The map label for this gene is mdoH

Identifier: 45657786

GI number: 45657786

Start: 2328516

End: 2329649

Strand: Reverse

Name: mdoH

Synonym: LIC11926

Alternate gene names: 45657786

Gene position: 2329649-2328516 (Counterclockwise)

Preceding gene: 45657787

Following gene: 45657785

Centisome position: 54.47

GC content: 35.19

Gene sequence:

>1134_bases
ATGAAAAAAAAGAATATCACCTATGTAATCCCGTGTTTGAACGAGGAAAAAACTCTTCCTCTTGTTTTAGAAAAATTAGT
TCGGCTCAAAAAAGAATTAAAACAATATAATGTGGAAATTTTGGTTTCGGACAACGGAAGTGAAGATAAATCCGTATCCA
TTGCAAAAAAATATGGAGCTAAAGTAGTACATTGTAAAGAAAGAGGTTACGGAGCTGCTCTCAATTTTGGAATCATAAAC
GCAAACGGAGAAATTGTACTTTTTGCGGATGCGGATGATACTTACGACTTTTTAGAATCACCAGCACTTCTTGCTGAAAT
GGAGAAAGGTGCAGAGTTTGTGATTGGTTCTAGACTTGACGGAACTATTTATAAAGGGGCGATGCCTTTTTTACATCGTT
ATTTAGGAACACCGGTTATCAATTGGATTATTAATTTATTATATTCTAAAAGAGGAAATCGTGTTAGAGATTCAAATTCG
GGTTTTCGTTGTTTTTTAAAAAAGAAATATCTAGAATGGGAGATAGAAAGTACTGGGATGGAATTTGCTTCTGAGATGTT
GGTAAAAGCGCTTAGAAGTGGAGTTAAACTTTCTCATGTGCCAATTAGTTTACACCCAGACGTAGCGGGAAGAATTCCTC
ATCTAAGAACTTGGAGGGATGGGATGAGGCATCTTTTGCAGATACTCATTCATTCTCAGCAACTGTTTTATTACACTGGC
TTTACTCTATTTTGGATAGGTTGGGTAGTCACAATTTTAGGGTATTTTACTGGAATTATTGCCATCGGTCCTTTTCATAT
TTTTGGAATTCATTCTCTTACTGTTTCTCTATTAGTCGCTACTTTAGGTCAGACCGTTTGGGCGATCGGGTTATTTTTGG
CCGCTCGAAAAATTCCAGAACTCAAATTGTATTCGAAACTGATTCACTTATCCGAAGATCTTTTGTTTTGGTATTCAGCG
AGAATGATATTAGTCGTAATTTTACTTTTTGCTTTTATTGTATTTCGTTGGTGGAGAAACTCTTTTCAGCTTTTGGATTT
AGAGAAAGAAATTTTAATGATTAGTTTTTTAAGTGTCCAAATTTTGAATGCAATTGGACAAACGATCACTGCTCACTTAT
TGAAAAGGACGTAA

Upstream 100 bases:

>100_bases
ATCATTATTTATGCGTAGTAACTTTGATAGAAAAGATCAATTGTTTTACGGGATGAGAGTCGTCACGATTCGCAAAAAGT
AAATTCCGGAATTTTAAACT

Downstream 100 bases:

>100_bases
CTTACGGAATCTGCATTGCGGTTTTTCGATTGGGTTCAGAAAAAACGATAGAATTAAAAAAATAGATGCTTTTTTTGTTC
TTATATAAGTGAGATTTTGG

Product: dolichol-P-glucose synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MKKKNITYVIPCLNEEKTLPLVLEKLVRLKKELKQYNVEILVSDNGSEDKSVSIAKKYGAKVVHCKERGYGAALNFGIIN
ANGEIVLFADADDTYDFLESPALLAEMEKGAEFVIGSRLDGTIYKGAMPFLHRYLGTPVINWIINLLYSKRGNRVRDSNS
GFRCFLKKKYLEWEIESTGMEFASEMLVKALRSGVKLSHVPISLHPDVAGRIPHLRTWRDGMRHLLQILIHSQQLFYYTG
FTLFWIGWVVTILGYFTGIIAIGPFHIFGIHSLTVSLLVATLGQTVWAIGLFLAARKIPELKLYSKLIHLSEDLLFWYSA
RMILVVILLFAFIVFRWWRNSFQLLDLEKEILMISFLSVQILNAIGQTITAHLLKRT

Sequences:

>Translated_377_residues
MKKKNITYVIPCLNEEKTLPLVLEKLVRLKKELKQYNVEILVSDNGSEDKSVSIAKKYGAKVVHCKERGYGAALNFGIIN
ANGEIVLFADADDTYDFLESPALLAEMEKGAEFVIGSRLDGTIYKGAMPFLHRYLGTPVINWIINLLYSKRGNRVRDSNS
GFRCFLKKKYLEWEIESTGMEFASEMLVKALRSGVKLSHVPISLHPDVAGRIPHLRTWRDGMRHLLQILIHSQQLFYYTG
FTLFWIGWVVTILGYFTGIIAIGPFHIFGIHSLTVSLLVATLGQTVWAIGLFLAARKIPELKLYSKLIHLSEDLLFWYSA
RMILVVILLFAFIVFRWWRNSFQLLDLEKEILMISFLSVQILNAIGQTITAHLLKRT
>Mature_377_residues
MKKKNITYVIPCLNEEKTLPLVLEKLVRLKKELKQYNVEILVSDNGSEDKSVSIAKKYGAKVVHCKERGYGAALNFGIIN
ANGEIVLFADADDTYDFLESPALLAEMEKGAEFVIGSRLDGTIYKGAMPFLHRYLGTPVINWIINLLYSKRGNRVRDSNS
GFRCFLKKKYLEWEIESTGMEFASEMLVKALRSGVKLSHVPISLHPDVAGRIPHLRTWRDGMRHLLQILIHSQQLFYYTG
FTLFWIGWVVTILGYFTGIIAIGPFHIFGIHSLTVSLLVATLGQTVWAIGLFLAARKIPELKLYSKLIHLSEDLLFWYSA
RMILVVILLFAFIVFRWWRNSFQLLDLEKEILMISFLSVQILNAIGQTITAHLLKRT

Specific function: Involved In O Antigen Modification. Catalyzes The Transfer Of The Glucose Residue From Udp-Glucose To A Lipid Carrier (By Similarity). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family [H]

Homologues:

Organism=Homo sapiens, GI7019323, Length=119, Percent_Identity=36.1344537815126, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: 2.4.1.- [C]

Molecular weight: Translated: 43042; Mature: 43042

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKNITYVIPCLNEEKTLPLVLEKLVRLKKELKQYNVEILVSDNGSEDKSVSIAKKYGA
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHCC
KVVHCKERGYGAALNFGIINANGEIVLFADADDTYDFLESPALLAEMEKGAEFVIGSRLD
EEEEEECCCCCEEEEEEEEECCCCEEEEECCCCCHHHHCCCHHHHHHHCCCCEEECCCCC
GTIYKGAMPFLHRYLGTPVINWIINLLYSKRGNRVRDSNSGFRCFLKKKYLEWEIESTGM
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHEEEEHHHHH
EFASEMLVKALRSGVKLSHVPISLHPDVAGRIPHLRTWRDGMRHLLQILIHSQQLFYYTG
HHHHHHHHHHHHCCCEEEECCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHEEHHH
FTLFWIGWVVTILGYFTGIIAIGPFHIFGIHSLTVSLLVATLGQTVWAIGLFLAARKIPE
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
LKLYSKLIHLSEDLLFWYSARMILVVILLFAFIVFRWWRNSFQLLDLEKEILMISFLSVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHH
ILNAIGQTITAHLLKRT
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKKNITYVIPCLNEEKTLPLVLEKLVRLKKELKQYNVEILVSDNGSEDKSVSIAKKYGA
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHCC
KVVHCKERGYGAALNFGIINANGEIVLFADADDTYDFLESPALLAEMEKGAEFVIGSRLD
EEEEEECCCCCEEEEEEEEECCCCEEEEECCCCCHHHHCCCHHHHHHHCCCCEEECCCCC
GTIYKGAMPFLHRYLGTPVINWIINLLYSKRGNRVRDSNSGFRCFLKKKYLEWEIESTGM
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEHHHHEEEEHHHHH
EFASEMLVKALRSGVKLSHVPISLHPDVAGRIPHLRTWRDGMRHLLQILIHSQQLFYYTG
HHHHHHHHHHHHCCCEEEECCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHEEHHH
FTLFWIGWVVTILGYFTGIIAIGPFHIFGIHSLTVSLLVATLGQTVWAIGLFLAARKIPE
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
LKLYSKLIHLSEDLLFWYSARMILVVILLFAFIVFRWWRNSFQLLDLEKEILMISFLSVQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHH
ILNAIGQTITAHLLKRT
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]