Click here to switch to the map view.

The map label for this gene is wecG

Identifier: 45657774

GI number: 45657774

Start: 2312284

End: 2313111

Strand: Reverse

Name: wecG

Synonym: LIC11914

Alternate gene names: 45657774

Gene position: 2313111-2312284 (Counterclockwise)

Preceding gene: 45657775

Following gene: 45657766

Centisome position: 54.08

GC content: 36.71

Gene sequence:

>828_bases
ATGAAAAAGCCAGGTGAAATTATACATCTATCCGCAAAGGATGACAGAGATTATCTTTTGGATTATCAGGTAATTCAAAC
GGAGACGTTAGGAAAAACCGATATTTTAGGAGTCCAGTTTGATAATGTAACTCAAGATGAATCCGTGGCTAAAATTTATA
GACTTATGGAGGAAAAGGAAAAGTTTCATCACATTCTTTTTTTAGATCCGATTAAAATCATGTCGGTTCGAAAGGGAAAA
AAACTCCATAGAATTACTGAAAAAGCCACTATGATTCTTGCGGAAGGCGCGGGATTACAATGGGCGGCGACTCGTCTTAG
GAGAGTTCTTAAGGAAAGAATTTCTCCGATAGCTTTGATGATGGATTTGGTTCGTCTTTGCGAACTTAGAAATTATTCTA
TCTTTATGTTAGGTGGTAAAGAAGACATTATTGAAAGAGTGTATTTTACTCTTTCAAGACATTTTCCTGGAGTGAGAATT
GTAGGAAGGCACGCTGGTTATATGAATCCTCAGAGGGAATTGATGGTAAAGGAATCGATTCGTAAGACGAGCCCCAATCT
GATTTTTCTTGCAATGGATTTTCCGGAACAAGAAATTTGGATTGAAAACAATACAGCATTCTTTGGACACTCCGTGATCA
TTGGGGTTGGCGGCTCTTTGGATATTCTTTCCGGGAAAGTAAGAAAGGCTCCTAATTTTTTTAAACTCAAAGGGCTCATT
TGGTTGTGGAGAATTCTTTCTAAACCTTGGAGACTTTTTCGTTTTTTTAGAATGTTCCAATTCTTTACTTTAGTATTCTT
TAAATCTCTCTTCCAAAAGAAATCTTAG

Upstream 100 bases:

>100_bases
TTTAGAAAATGAATTTAGGACCGCCGCCACGAAATTACGGAAATAAATTTAGGTAAGTTTCAATTGACTCTAAGTTTATG
TCGTATAGTATGCCTTTAAG

Downstream 100 bases:

>100_bases
TAACTTGAGTTCAGTTGTAAAGAACTGAATTTTTATAAAGAGATTATCTAAAAATCTAGAAACTATCTTAATTAACGTGA
GTTCGGCTATGATTCATTTT

Product: UDP-n-acetyl-d-mannosamine transferase

Products: NA

Alternate protein names: Major teichoic acid biosynthesis protein A; N-acetylglucosaminyldiphospho-undecaprenol N-acetyl-beta-D-mannosaminyltransferase; UDP-N-acetylmannosamine transferase [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MKKPGEIIHLSAKDDRDYLLDYQVIQTETLGKTDILGVQFDNVTQDESVAKIYRLMEEKEKFHHILFLDPIKIMSVRKGK
KLHRITEKATMILAEGAGLQWAATRLRRVLKERISPIALMMDLVRLCELRNYSIFMLGGKEDIIERVYFTLSRHFPGVRI
VGRHAGYMNPQRELMVKESIRKTSPNLIFLAMDFPEQEIWIENNTAFFGHSVIIGVGGSLDILSGKVRKAPNFFKLKGLI
WLWRILSKPWRLFRFFRMFQFFTLVFFKSLFQKKS

Sequences:

>Translated_275_residues
MKKPGEIIHLSAKDDRDYLLDYQVIQTETLGKTDILGVQFDNVTQDESVAKIYRLMEEKEKFHHILFLDPIKIMSVRKGK
KLHRITEKATMILAEGAGLQWAATRLRRVLKERISPIALMMDLVRLCELRNYSIFMLGGKEDIIERVYFTLSRHFPGVRI
VGRHAGYMNPQRELMVKESIRKTSPNLIFLAMDFPEQEIWIENNTAFFGHSVIIGVGGSLDILSGKVRKAPNFFKLKGLI
WLWRILSKPWRLFRFFRMFQFFTLVFFKSLFQKKS
>Mature_275_residues
MKKPGEIIHLSAKDDRDYLLDYQVIQTETLGKTDILGVQFDNVTQDESVAKIYRLMEEKEKFHHILFLDPIKIMSVRKGK
KLHRITEKATMILAEGAGLQWAATRLRRVLKERISPIALMMDLVRLCELRNYSIFMLGGKEDIIERVYFTLSRHFPGVRI
VGRHAGYMNPQRELMVKESIRKTSPNLIFLAMDFPEQEIWIENNTAFFGHSVIIGVGGSLDILSGKVRKAPNFFKLKGLI
WLWRILSKPWRLFRFFRMFQFFTLVFFKSLFQKKS

Specific function: Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, a key lipid intermediate in the de novo synthesis of teichoic acid (Potential) [H]

COG id: COG1922

COG function: function code M; Teichoic acid biosynthesis proteins

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 26 family [H]

Homologues:

Organism=Escherichia coli, GI2367289, Length=140, Percent_Identity=29.2857142857143, Blast_Score=81, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004629 [H]

Pfam domain/function: PF03808 Glyco_tran_WecB [H]

EC number: =2.4.1.187 [H]

Molecular weight: Translated: 32262; Mature: 32262

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKPGEIIHLSAKDDRDYLLDYQVIQTETLGKTDILGVQFDNVTQDESVAKIYRLMEEKE
CCCCCCEEEEECCCCCCCEEEEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHH
KFHHILFLDPIKIMSVRKGKKLHRITEKATMILAEGAGLQWAATRLRRVLKERISPIALM
HHCEEEEECCHHHHHHHCCHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
MDLVRLCELRNYSIFMLGGKEDIIERVYFTLSRHFPGVRIVGRHAGYMNPQRELMVKESI
HHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHH
RKTSPNLIFLAMDFPEQEIWIENNTAFFGHSVIIGVGGSLDILSGKVRKAPNFFKLKGLI
HHCCCCEEEEEECCCCCEEEEECCCEEEECEEEEECCCCHHHHCCHHHCCCCHHHHHHHH
WLWRILSKPWRLFRFFRMFQFFTLVFFKSLFQKKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKPGEIIHLSAKDDRDYLLDYQVIQTETLGKTDILGVQFDNVTQDESVAKIYRLMEEKE
CCCCCCEEEEECCCCCCCEEEEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHH
KFHHILFLDPIKIMSVRKGKKLHRITEKATMILAEGAGLQWAATRLRRVLKERISPIALM
HHCEEEEECCHHHHHHHCCHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
MDLVRLCELRNYSIFMLGGKEDIIERVYFTLSRHFPGVRIVGRHAGYMNPQRELMVKESI
HHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHH
RKTSPNLIFLAMDFPEQEIWIENNTAFFGHSVIIGVGGSLDILSGKVRKAPNFFKLKGLI
HHCCCCEEEEEECCCCCEEEEECCCEEEECEEEEECCCCHHHHCCHHHCCCCHHHHHHHH
WLWRILSKPWRLFRFFRMFQFFTLVFFKSLFQKKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA