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The map label for this gene is creB [H]

Identifier: 45657759

GI number: 45657759

Start: 2293595

End: 2294317

Strand: Reverse

Name: creB [H]

Synonym: LIC11896

Alternate gene names: 45657759

Gene position: 2294317-2293595 (Counterclockwise)

Preceding gene: 45657764

Following gene: 45657758

Centisome position: 53.64

GC content: 37.07

Gene sequence:

>723_bases
ATGGGGCAAAAATCTTCTTTTCCTAAAAATGAGATCGATTTTTTATTTTCGTGGATGCGTACAATTCTACTCACAGAAGA
CGAGCCGGGGATTCGAGATACGATTCAAATCGTTTTGGAATCGGAAGGTTTTAAAATGATCTACGCGATGACTGGTAAAG
AATGTATTTCTCTTTTGAAAGAATCCCCAGACTTATTGGTGCTGGATGTGGGACTTCCAGATGGAAGTGGTTTTGAAATT
TTGAAAGAACTTAGAAAGAAAAATTCGATTCCAGTTATTTTACTTACCGCCAGAGAATCGGAACTTGACAGGGTTCTTGG
TTTAGAGTTAGGTGCAGATGACTATATGGTAAAACCTTTTAGCCCTAGAGAATTGGTCGCCAGAATCAAAGCGGTGTTAA
GAAGGTATGATGGAAACTCTGAAAAAAAACAAACAGAGTTTCTCACGGATGAAGATCGTAAGATTATCTATTATTACGGT
AAGTCTTTATCTCTTACTCCGTATGAGTATAAAACGTTATTATTATTTTTAAAACGACCTGGAAAAATTTTTACAAGAGA
AGAAATTATGGATCGAGTTTGGACGGAACCGGAAGAAAGTTTTGATCGTGCCGTAGACACTGTAATTAAAAACATTCGCT
TTCGATTAAAAGAAATTCGACCTGACTTAGATCCGATTGAAACGAAACGGGGTCAAGGATACGGATTGAAGGATACGTTA
TGA

Upstream 100 bases:

>100_bases
CATAAAATTTAAGTTGTTAAAACAATCGCAAAGTATCTTTCGAGAAGCGACTTATGCAAACCGATTTCGTTTCTAACTTA
AAAAAATTCCAAAGTTTTGG

Downstream 100 bases:

>100_bases
GTCTTTTGATCCGAATTGTAATCGGTTTTTTTTTGCCTTCTTTATCGGTTATTATTACTTTGTAGATAAAATCGAAGAAT
CGATTCGGCCACGTTATATG

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MGQKSSFPKNEIDFLFSWMRTILLTEDEPGIRDTIQIVLESEGFKMIYAMTGKECISLLKESPDLLVLDVGLPDGSGFEI
LKELRKKNSIPVILLTARESELDRVLGLELGADDYMVKPFSPRELVARIKAVLRRYDGNSEKKQTEFLTDEDRKIIYYYG
KSLSLTPYEYKTLLLFLKRPGKIFTREEIMDRVWTEPEESFDRAVDTVIKNIRFRLKEIRPDLDPIETKRGQGYGLKDTL

Sequences:

>Translated_240_residues
MGQKSSFPKNEIDFLFSWMRTILLTEDEPGIRDTIQIVLESEGFKMIYAMTGKECISLLKESPDLLVLDVGLPDGSGFEI
LKELRKKNSIPVILLTARESELDRVLGLELGADDYMVKPFSPRELVARIKAVLRRYDGNSEKKQTEFLTDEDRKIIYYYG
KSLSLTPYEYKTLLLFLKRPGKIFTREEIMDRVWTEPEESFDRAVDTVIKNIRFRLKEIRPDLDPIETKRGQGYGLKDTL
>Mature_239_residues
GQKSSFPKNEIDFLFSWMRTILLTEDEPGIRDTIQIVLESEGFKMIYAMTGKECISLLKESPDLLVLDVGLPDGSGFEIL
KELRKKNSIPVILLTARESELDRVLGLELGADDYMVKPFSPRELVARIKAVLRRYDGNSEKKQTEFLTDEDRKIIYYYGK
SLSLTPYEYKTLLLFLKRPGKIFTREEIMDRVWTEPEESFDRAVDTVIKNIRFRLKEIRPDLDPIETKRGQGYGLKDTL

Specific function: Member of the two-component regulatory system CreC/CreB involved in catabolic regulation [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=44.3946188340807, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI1788394, Length=218, Percent_Identity=35.7798165137615, Blast_Score=147, Evalue=5e-37,
Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=40.0900900900901, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=41.4096916299559, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1786911, Length=181, Percent_Identity=35.3591160220994, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1790863, Length=225, Percent_Identity=33.3333333333333, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=35.2941176470588, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=32.3008849557522, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790552, Length=219, Percent_Identity=34.703196347032, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI87082012, Length=215, Percent_Identity=35.8139534883721, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=34.9775784753363, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1787375, Length=217, Percent_Identity=30.4147465437788, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1789809, Length=224, Percent_Identity=31.6964285714286, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=28.1385281385281, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788550, Length=148, Percent_Identity=29.7297297297297, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27842; Mature: 27710

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQKSSFPKNEIDFLFSWMRTILLTEDEPGIRDTIQIVLESEGFKMIYAMTGKECISLLK
CCCCCCCCCHHHHHHHHHHHHHEECCCCCCHHHHHHHEECCCCCEEEEEECCHHHHHHHH
ESPDLLVLDVGLPDGSGFEILKELRKKNSIPVILLTARESELDRVLGLELGADDYMVKPF
CCCCEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHEECCCCCEECCC
SPRELVARIKAVLRRYDGNSEKKQTEFLTDEDRKIIYYYGKSLSLTPYEYKTLLLFLKRP
CHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCC
GKIFTREEIMDRVWTEPEESFDRAVDTVIKNIRFRLKEIRPDLDPIETKRGQGYGLKDTL
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCC
>Mature Secondary Structure 
GQKSSFPKNEIDFLFSWMRTILLTEDEPGIRDTIQIVLESEGFKMIYAMTGKECISLLK
CCCCCCCCHHHHHHHHHHHHHEECCCCCCHHHHHHHEECCCCCEEEEEECCHHHHHHHH
ESPDLLVLDVGLPDGSGFEILKELRKKNSIPVILLTARESELDRVLGLELGADDYMVKPF
CCCCEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHEECCCCCEECCC
SPRELVARIKAVLRRYDGNSEKKQTEFLTDEDRKIIYYYGKSLSLTPYEYKTLLLFLKRP
CHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCC
GKIFTREEIMDRVWTEPEESFDRAVDTVIKNIRFRLKEIRPDLDPIETKRGQGYGLKDTL
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3531171; 7610040; 9278503 [H]