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The map label for this gene is gmhA

Identifier: 45657690

GI number: 45657690

Start: 2219933

End: 2220520

Strand: Reverse

Name: gmhA

Synonym: LIC11825

Alternate gene names: 45657690

Gene position: 2220520-2219933 (Counterclockwise)

Preceding gene: 45657691

Following gene: 45657689

Centisome position: 51.92

GC content: 39.63

Gene sequence:

>588_bases
ATGGATATTAAAGAAATCGCCCTCGGTCAGATTCGGGATTCTATTGCCACCAAACAGAAATGTATTGATTCAATTTTAGA
AGACATCATAAAAGCTGGTGAAATCGTTTCCAAGATTCTACAGGCTGGGAACACGATTTTTCTTTGTGGAAACGGAGGAT
CTTCTTGTGACGCTTCTCATATCGCTGCGGAATTGGTAGTTCGATATAAGTCCGGAAATGAAAGAAAGGCGCTACCCGCA
CTTTCTCTTTCTGCTGATTCCGCCGTTTTGACTGCTTGTTCTAATGACTACGGCTACGAAGAAATTTTTTCAAGACAAAT
AGAAGCTTTTGGTAGAAAGGGAGATTTATTGATTGGGCTTTCTACAAGTGGAAATTCTAAAAACGTTTTACTGGCGCTGG
AAAAAGCAAAAACGAGAGGAGTAAAAACCATATCGTTGTTAGGTGGTGACGGCGGAAAAATGAAAAATCTTTCTGACTTG
GACGTTATCGTTCCGAGTAACGTGACCGCTAGAATCCAAGAATCTCATATTTTAATCGGGCATATCATCTGTAGTATCGT
GGAATATAACCTTTTCAAAATGGAATGA

Upstream 100 bases:

>100_bases
CCGTATACGGAAAATCTTTCTCTTCAGGATTTTGAAAAAGCAAAGAAGGAATTTTTTCAAGTGCTCGAACAGATTCGAAA
AAAAAGAGGAAACACCTAAG

Downstream 100 bases:

>100_bases
CCTGTTTGTTGTGAATTCTGTTGCCATAGAAATTTCTAATCTTAAGGTTTCCACTCCTGGCTGCCACATTCTTAAAGGAA
TCGATTTTACACTCGATGTA

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MDIKEIALGQIRDSIATKQKCIDSILEDIIKAGEIVSKILQAGNTIFLCGNGGSSCDASHIAAELVVRYKSGNERKALPA
LSLSADSAVLTACSNDYGYEEIFSRQIEAFGRKGDLLIGLSTSGNSKNVLLALEKAKTRGVKTISLLGGDGGKMKNLSDL
DVIVPSNVTARIQESHILIGHIICSIVEYNLFKME

Sequences:

>Translated_195_residues
MDIKEIALGQIRDSIATKQKCIDSILEDIIKAGEIVSKILQAGNTIFLCGNGGSSCDASHIAAELVVRYKSGNERKALPA
LSLSADSAVLTACSNDYGYEEIFSRQIEAFGRKGDLLIGLSTSGNSKNVLLALEKAKTRGVKTISLLGGDGGKMKNLSDL
DVIVPSNVTARIQESHILIGHIICSIVEYNLFKME
>Mature_195_residues
MDIKEIALGQIRDSIATKQKCIDSILEDIIKAGEIVSKILQAGNTIFLCGNGGSSCDASHIAAELVVRYKSGNERKALPA
LSLSADSAVLTACSNDYGYEEIFSRQIEAFGRKGDLLIGLSTSGNSKNVLLALEKAKTRGVKTISLLGGDGGKMKNLSDL
DVIVPSNVTARIQESHILIGHIICSIVEYNLFKME

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1786416, Length=172, Percent_Identity=43.0232558139535, Blast_Score=144, Evalue=3e-36,
Organism=Escherichia coli, GI1789539, Length=186, Percent_Identity=36.5591397849462, Blast_Score=141, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 20857; Mature: 20857

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKEIALGQIRDSIATKQKCIDSILEDIIKAGEIVSKILQAGNTIFLCGNGGSSCDASH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHH
IAAELVVRYKSGNERKALPALSLSADSAVLTACSNDYGYEEIFSRQIEAFGRKGDLLIGL
HHHHHHHEECCCCCCCCCCEEECCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEE
STSGNSKNVLLALEKAKTRGVKTISLLGGDGGKMKNLSDLDVIVPSNVTARIQESHILIG
ECCCCCCEEEEEEECHHCCCCEEEEEEECCCCCCCCCCCCEEECCCCCEEEEECCEEHHH
HIICSIVEYNLFKME
HHHHHHHHHHHEECC
>Mature Secondary Structure
MDIKEIALGQIRDSIATKQKCIDSILEDIIKAGEIVSKILQAGNTIFLCGNGGSSCDASH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHH
IAAELVVRYKSGNERKALPALSLSADSAVLTACSNDYGYEEIFSRQIEAFGRKGDLLIGL
HHHHHHHEECCCCCCCCCCEEECCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEE
STSGNSKNVLLALEKAKTRGVKTISLLGGDGGKMKNLSDLDVIVPSNVTARIQESHILIG
ECCCCCCEEEEEEECHHCCCCEEEEEEECCCCCCCCCCCCEEECCCCCEEEEECCEEHHH
HIICSIVEYNLFKME
HHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA