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The map label for this gene is oppD

Identifier: 45657689

GI number: 45657689

Start: 2219161

End: 2219922

Strand: Reverse

Name: oppD

Synonym: LIC11824

Alternate gene names: 45657689

Gene position: 2219922-2219161 (Counterclockwise)

Preceding gene: 45657690

Following gene: 45657688

Centisome position: 51.9

GC content: 37.14

Gene sequence:

>762_bases
GTGAATTCTGTTGCCATAGAAATTTCTAATCTTAAGGTTTCCACTCCTGGCTGCCACATTCTTAAAGGAATCGATTTTAC
ACTCGATGTAGGAGATGTACATTGTATCTTAGGAGAATCTGGAAGCGGCAAATCTACGTTTGCGTCTTGTCTTTTGGGAA
CGACCGAAAAAGAGCTCTTTCTAAGGTCTGATCGTTTTTTTCTGTTAGGCCAAGACGTTCGGTATTTTACCGAAAGAGAG
TGGCAGAATGTTCGAGGAAAAAAAATTGCGTTGATTCCACAAAATCCGATTTGGGGTTTTCATCCATATCGAAAAACTGG
ATCTCAGATTTTAGAAGCGTTTTCACTTTACAACCTAAAACTCGCAGAGAAAAAGAAAATTTTATCTTTATTAGAATCCA
TTTTCATTTTAGAACCGGAAAAAGTTTTCGATTCTCTTCCAAGTTATCTTTCTGGAGGAGAGAGACAGAGGATTTTGATT
CTTTTAGCGGTTTATTCTGGGGCAGAAATTGTTGTGGCGGATGAACCAACTGCAGCCTTGGATTCGATCAGCGAAACAGA
AGTTCTCAAACTTTTGATGAAATTCAGAAAAGAAAAAGAACTTTCTCTTATTTTTATTACTCATGAAATCTCTATCGCCA
AATCTTTGGCCGATACTATAAGTATCCTTTATCAGGGAGATTGGGCTGAAATTCTCAAAAGACCAATTCAGGGAGAATGG
ATTGTTAAATCTGAGTATGGAAAAAGACTTTTTGAAAGTTGA

Upstream 100 bases:

>100_bases
AACGTGACCGCTAGAATCCAAGAATCTCATATTTTAATCGGGCATATCATCTGTAGTATCGTGGAATATAACCTTTTCAA
AATGGAATGACCTGTTTGTT

Downstream 100 bases:

>100_bases
TCTCAGATAGTAGAGTGCGAACGATGAGGTATGCAGTTTTACTGACGTTAATTTTATTTTTTTCTCCGCTTTGGGCGCAG
AAGTCTCCTTTTATCGTGGA

Product: ABC transporter ATP-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Stage 0 sporulation protein KD [H]

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MNSVAIEISNLKVSTPGCHILKGIDFTLDVGDVHCILGESGSGKSTFASCLLGTTEKELFLRSDRFFLLGQDVRYFTERE
WQNVRGKKIALIPQNPIWGFHPYRKTGSQILEAFSLYNLKLAEKKKILSLLESIFILEPEKVFDSLPSYLSGGERQRILI
LLAVYSGAEIVVADEPTAALDSISETEVLKLLMKFRKEKELSLIFITHEISIAKSLADTISILYQGDWAEILKRPIQGEW
IVKSEYGKRLFES

Sequences:

>Translated_253_residues
MNSVAIEISNLKVSTPGCHILKGIDFTLDVGDVHCILGESGSGKSTFASCLLGTTEKELFLRSDRFFLLGQDVRYFTERE
WQNVRGKKIALIPQNPIWGFHPYRKTGSQILEAFSLYNLKLAEKKKILSLLESIFILEPEKVFDSLPSYLSGGERQRILI
LLAVYSGAEIVVADEPTAALDSISETEVLKLLMKFRKEKELSLIFITHEISIAKSLADTISILYQGDWAEILKRPIQGEW
IVKSEYGKRLFES
>Mature_253_residues
MNSVAIEISNLKVSTPGCHILKGIDFTLDVGDVHCILGESGSGKSTFASCLLGTTEKELFLRSDRFFLLGQDVRYFTERE
WQNVRGKKIALIPQNPIWGFHPYRKTGSQILEAFSLYNLKLAEKKKILSLLESIFILEPEKVFDSLPSYLSGGERQRILI
LLAVYSGAEIVVADEPTAALDSISETEVLKLLMKFRKEKELSLIFITHEISIAKSLADTISILYQGDWAEILKRPIQGEW
IVKSEYGKRLFES

Specific function: Part of the binding protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. Required for sporulation and competence [H]

COG id: COG0444

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI21536376, Length=228, Percent_Identity=28.0701754385965, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI116734710, Length=209, Percent_Identity=26.3157894736842, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI1789963, Length=209, Percent_Identity=30.622009569378, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1787759, Length=237, Percent_Identity=29.957805907173, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1788506, Length=216, Percent_Identity=32.4074074074074, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI145693107, Length=218, Percent_Identity=33.0275229357798, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI48994883, Length=231, Percent_Identity=29.8701298701299, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1789962, Length=213, Percent_Identity=34.2723004694836, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1787548, Length=236, Percent_Identity=25.4237288135593, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1787500, Length=214, Percent_Identity=28.9719626168224, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1787758, Length=222, Percent_Identity=30.6306306306306, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789890, Length=227, Percent_Identity=28.6343612334802, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1787105, Length=235, Percent_Identity=30.6382978723404, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786398, Length=212, Percent_Identity=28.3018867924528, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1787547, Length=212, Percent_Identity=27.8301886792453, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1787792, Length=218, Percent_Identity=31.1926605504587, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1788225, Length=234, Percent_Identity=28.6324786324786, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI48994997, Length=244, Percent_Identity=28.6885245901639, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789032, Length=212, Percent_Identity=27.3584905660377, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788761, Length=231, Percent_Identity=27.2727272727273, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1786703, Length=217, Percent_Identity=29.9539170506912, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1789891, Length=238, Percent_Identity=24.7899159663866, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1786345, Length=241, Percent_Identity=26.9709543568465, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87081834, Length=230, Percent_Identity=25.6521739130435, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789672, Length=223, Percent_Identity=28.6995515695067, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788472, Length=245, Percent_Identity=26.9387755102041, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1787370, Length=225, Percent_Identity=22.6666666666667, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1786563, Length=230, Percent_Identity=25.6521739130435, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI87081709, Length=226, Percent_Identity=22.1238938053097, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1789864, Length=233, Percent_Identity=24.4635193133047, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081791, Length=226, Percent_Identity=23.8938053097345, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI87082267, Length=220, Percent_Identity=25.4545454545455, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1786981, Length=219, Percent_Identity=28.7671232876712, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787089, Length=216, Percent_Identity=25.9259259259259, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788450, Length=237, Percent_Identity=23.6286919831224, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787972, Length=234, Percent_Identity=26.0683760683761, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71996550, Length=239, Percent_Identity=30.1255230125523, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115534520, Length=262, Percent_Identity=28.2442748091603, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17541710, Length=230, Percent_Identity=27.8260869565217, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193208177, Length=244, Percent_Identity=29.0983606557377, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17565938, Length=223, Percent_Identity=26.0089686098655, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI115533608, Length=226, Percent_Identity=28.7610619469027, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323959, Length=217, Percent_Identity=28.110599078341, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24650853, Length=209, Percent_Identity=25.8373205741627, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650855, Length=209, Percent_Identity=25.8373205741627, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281362751, Length=215, Percent_Identity=26.5116279069767, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR010066
- InterPro:   IPR013563 [H]

Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]

EC number: NA

Molecular weight: Translated: 28547; Mature: 28547

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSVAIEISNLKVSTPGCHILKGIDFTLDVGDVHCILGESGSGKSTFASCLLGTTEKELF
CCCEEEEEECEEEECCCCEEEECCCEEEECCCEEEEECCCCCCHHHHHHHHHCCCCHHHE
LRSDRFFLLGQDVRYFTEREWQNVRGKKIALIPQNPIWGFHPYRKTGSQILEAFSLYNLK
EECCCEEEEECCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCC
LAEKKKILSLLESIFILEPEKVFDSLPSYLSGGERQRILILLAVYSGAEIVVADEPTAAL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEEEEECCCEEEEECCCCHHH
DSISETEVLKLLMKFRKEKELSLIFITHEISIAKSLADTISILYQGDWAEILKRPIQGEW
HCCCHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCE
IVKSEYGKRLFES
EEECHHHHHHHCC
>Mature Secondary Structure
MNSVAIEISNLKVSTPGCHILKGIDFTLDVGDVHCILGESGSGKSTFASCLLGTTEKELF
CCCEEEEEECEEEECCCCEEEECCCEEEECCCEEEEECCCCCCHHHHHHHHHCCCCHHHE
LRSDRFFLLGQDVRYFTEREWQNVRGKKIALIPQNPIWGFHPYRKTGSQILEAFSLYNLK
EECCCEEEEECCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCC
LAEKKKILSLLESIFILEPEKVFDSLPSYLSGGERQRILILLAVYSGAEIVVADEPTAAL
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEEEEECCCEEEEECCCCHHH
DSISETEVLKLLMKFRKEKELSLIFITHEISIAKSLADTISILYQGDWAEILKRPIQGEW
HCCCHHHHHHHHHHHCCCCCEEEEEEEEHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCE
IVKSEYGKRLFES
EEECHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1901616; 1899858; 9384377 [H]