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The map label for this gene is rnhB

Identifier: 45657433

GI number: 45657433

Start: 1921387

End: 1922082

Strand: Direct

Name: rnhB

Synonym: LIC11560

Alternate gene names: 45657433

Gene position: 1921387-1922082 (Clockwise)

Preceding gene: 45657432

Following gene: 45657434

Centisome position: 44.92

GC content: 34.34

Gene sequence:

>696_bases
TTGCCGGAACCGAAACTTTCCAATTTTTTTGAATTAGAAGAACACCGATTTTATTCGGAGTCGATTCCATGTGGGATTGA
TGAGGCGGGAAGAGGTCCTTATGCGGGGCCTCTTTCTGTAGCTTTAGTTTCTTTTTCTCAAAATTCTCTTACTCAAATCC
TAGAAGGAAAAATTCTCAAGGGATTAACTGATTCCAAAAAACTTTCTGAAAAAAAAAGAGAATCTCTTTATCCTGAAATT
ATAAAGGCCGCACAATTTTCTTACCAAACTTTTATAAGTCCGAATTATATTGATCGGAAAGGTATCAATCGAGCCGTTTT
AGAAGGAATTTTAAAATGTACAAAATTGATAAACCGGTTTACTCAATCTAAATTTCCTCTAAAACTATTAATTGATGGGA
ATTATAACTTCAACCGTTACCCAGAATGGATGAATCTCAAAGGTTGTTCCACTTTTTATATAAAAGGGGATCTCAGAATT
GTAAGTATCGCCGCCGCTTCTATTCTTGCTAAAGTTAGCAGAGATCGTTATATGATTTCCGTTTCTAAAAAATATCCTAT
TTATCGTTTTGATCAACATAAAGGATACGGTACAAAACTTCACGAAGAACTGATTCTTCTACATGGTCTTTCCGATATTC
ATAGAAGAAGTTTTACCGGAAAGTTTCTAGAACAGATCTCAGAGTCTAATCTTTAA

Upstream 100 bases:

>100_bases
TATTAAAGAACTCAAAGGTGGTAAAGCTCTTGTAAGTGAAGACAGAAAGAGACAACAAGCTGCTGCGGCTACAAAATCTA
CGACGACGGAATAATCCGGT

Downstream 100 bases:

>100_bases
GAGATACGAAATTATCAGAAAGTTTTCGAGTGAGAGTAGTGTCTAAATAAGATACATTAAAGCGAGCGCTTATGAAACTT
TCAACGGATTTTTCTGTACG

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII [H]

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MPEPKLSNFFELEEHRFYSESIPCGIDEAGRGPYAGPLSVALVSFSQNSLTQILEGKILKGLTDSKKLSEKKRESLYPEI
IKAAQFSYQTFISPNYIDRKGINRAVLEGILKCTKLINRFTQSKFPLKLLIDGNYNFNRYPEWMNLKGCSTFYIKGDLRI
VSIAAASILAKVSRDRYMISVSKKYPIYRFDQHKGYGTKLHEELILLHGLSDIHRRSFTGKFLEQISESNL

Sequences:

>Translated_231_residues
MPEPKLSNFFELEEHRFYSESIPCGIDEAGRGPYAGPLSVALVSFSQNSLTQILEGKILKGLTDSKKLSEKKRESLYPEI
IKAAQFSYQTFISPNYIDRKGINRAVLEGILKCTKLINRFTQSKFPLKLLIDGNYNFNRYPEWMNLKGCSTFYIKGDLRI
VSIAAASILAKVSRDRYMISVSKKYPIYRFDQHKGYGTKLHEELILLHGLSDIHRRSFTGKFLEQISESNL
>Mature_230_residues
PEPKLSNFFELEEHRFYSESIPCGIDEAGRGPYAGPLSVALVSFSQNSLTQILEGKILKGLTDSKKLSEKKRESLYPEII
KAAQFSYQTFISPNYIDRKGINRAVLEGILKCTKLINRFTQSKFPLKLLIDGNYNFNRYPEWMNLKGCSTFYIKGDLRIV
SIAAASILAKVSRDRYMISVSKKYPIYRFDQHKGYGTKLHEELILLHGLSDIHRRSFTGKFLEQISESNL

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family [H]

Homologues:

Organism=Escherichia coli, GI1786380, Length=195, Percent_Identity=37.9487179487179, Blast_Score=109, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01351 RNase_HII [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 26474; Mature: 26343

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEPKLSNFFELEEHRFYSESIPCGIDEAGRGPYAGPLSVALVSFSQNSLTQILEGKILK
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHEECCCHHHHHHHHHHHHHH
GLTDSKKLSEKKRESLYPEIIKAAQFSYQTFISPNYIDRKGINRAVLEGILKCTKLINRF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
TQSKFPLKLLIDGNYNFNRYPEWMNLKGCSTFYIKGDLRIVSIAAASILAKVSRDRYMIS
HCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCEEEEHHHHHHHHHHHHCCEEEEE
VSKKYPIYRFDQHKGYGTKLHEELILLHGLSDIHRRSFTGKFLEQISESNL
ECCCCCEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PEPKLSNFFELEEHRFYSESIPCGIDEAGRGPYAGPLSVALVSFSQNSLTQILEGKILK
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHEECCCHHHHHHHHHHHHHH
GLTDSKKLSEKKRESLYPEIIKAAQFSYQTFISPNYIDRKGINRAVLEGILKCTKLINRF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
TQSKFPLKLLIDGNYNFNRYPEWMNLKGCSTFYIKGDLRIVSIAAASILAKVSRDRYMIS
HCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCEEEEHHHHHHHHHHHHCCEEEEE
VSKKYPIYRFDQHKGYGTKLHEELILLHGLSDIHRRSFTGKFLEQISESNL
ECCCCCEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA