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The map label for this gene is yfhM [H]

Identifier: 45657322

GI number: 45657322

Start: 1783392

End: 1784282

Strand: Direct

Name: yfhM [H]

Synonym: LIC11446

Alternate gene names: 45657322

Gene position: 1783392-1784282 (Clockwise)

Preceding gene: 45657320

Following gene: 45657323

Centisome position: 41.7

GC content: 35.8

Gene sequence:

>891_bases
ATGTCAGAAATCAAAACCTCTTTTTTAAAAAACGGAGAAAGAGAATATAAATATCTAAGTTTAGGGAATGGTAAAAAACT
TATTTTTTTCTTTCACGGATTTCCGGATGACGCCGGTTCTATGAAAGAACTAATGCAGATCTTTTCTAAAAAAGATTTTA
CGTGTATCGCTCCTTTTATGAGAGGATATTCTCCCGGTTCCAGTGTTCCTTTTTCTGGTACTGTCAGTATCGCCGAATTG
GCAGGAGATTTAAAATTTATCGTGGAATCTTTGAAGTCCGTGTACAATCCAGAAACTACCATTGTATTGGGGCACGATTG
GGGAGCAATTGCGTCCTATGCGTTTTCTAATCTTTCGCCAGGAATAATAGATACATTAGTCGCACTTTCCGTTCCTCCCA
TTCCTACGTATTTAAAAAATTTACTCGTTTATCCTTCTCAAATCGTTCGAAGTTGGTATATTTTATTTTTTCAAATTAGG
GCAGGAATTCCGGAAGCGGCATTGTTGAAAAATGATCTTTTACGTAGACTTTGGGAAGATTGGAGTCCTGGTTGGAAAAT
TCCCGAAGAACGGTTTAGAGAAGTTTTTGAAAATTTAAAAGTTCACGAAAATTTAATCACAGCGCTTGGTTATTATAGGG
GTTTATTAACTCCTGGAAATTTTGCTCTTTGGAATTCGAGTAGGGAATTAGTATTTCATAAAATTTCAGTTCCGACTTTA
ATACTCGCCGGAGAAAAAGACGAATGTATTTCCACTTCGGTATATAAAGGTCTTGAATCGGAATTTTATTCTAGGGTTTC
TTTCCAAGTAATTGACAAGGCGGGACATTTTTTACATTTAGAAGCGCCCGAACGGGTTGCAAAAGAAATATTTCGTTTTA
TTAAATTATAA

Upstream 100 bases:

>100_bases
ATAATAAGTTGTCGGAAATTTCGCTTCTAAGCGAAGATTTTTGCACTCAAATTTAAGGAATTTTATTATGCAAGTTTTCG
GTAAATAACCGGGAGTTTTC

Downstream 100 bases:

>100_bases
AATTAGTATATTTTTTAATATGAATGTTTTTTATGTAGCTATTTGTAGTATATTAGAATTGTTGAAAAAAATTCATAGAG
GCGGTTAATAAAATTGCTTC

Product: hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSEIKTSFLKNGEREYKYLSLGNGKKLIFFFHGFPDDAGSMKELMQIFSKKDFTCIAPFMRGYSPGSSVPFSGTVSIAEL
AGDLKFIVESLKSVYNPETTIVLGHDWGAIASYAFSNLSPGIIDTLVALSVPPIPTYLKNLLVYPSQIVRSWYILFFQIR
AGIPEAALLKNDLLRRLWEDWSPGWKIPEERFREVFENLKVHENLITALGYYRGLLTPGNFALWNSSRELVFHKISVPTL
ILAGEKDECISTSVYKGLESEFYSRVSFQVIDKAGHFLHLEAPERVAKEIFRFIKL

Sequences:

>Translated_296_residues
MSEIKTSFLKNGEREYKYLSLGNGKKLIFFFHGFPDDAGSMKELMQIFSKKDFTCIAPFMRGYSPGSSVPFSGTVSIAEL
AGDLKFIVESLKSVYNPETTIVLGHDWGAIASYAFSNLSPGIIDTLVALSVPPIPTYLKNLLVYPSQIVRSWYILFFQIR
AGIPEAALLKNDLLRRLWEDWSPGWKIPEERFREVFENLKVHENLITALGYYRGLLTPGNFALWNSSRELVFHKISVPTL
ILAGEKDECISTSVYKGLESEFYSRVSFQVIDKAGHFLHLEAPERVAKEIFRFIKL
>Mature_295_residues
SEIKTSFLKNGEREYKYLSLGNGKKLIFFFHGFPDDAGSMKELMQIFSKKDFTCIAPFMRGYSPGSSVPFSGTVSIAELA
GDLKFIVESLKSVYNPETTIVLGHDWGAIASYAFSNLSPGIIDTLVALSVPPIPTYLKNLLVYPSQIVRSWYILFFQIRA
GIPEAALLKNDLLRRLWEDWSPGWKIPEERFREVFENLKVHENLITALGYYRGLLTPGNFALWNSSRELVFHKISVPTLI
LAGEKDECISTSVYKGLESEFYSRVSFQVIDKAGHFLHLEAPERVAKEIFRFIKL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI218777840, Length=292, Percent_Identity=27.7397260273973, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI13376164, Length=292, Percent_Identity=27.7397260273973, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI218777837, Length=290, Percent_Identity=24.8275862068966, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17554012, Length=298, Percent_Identity=24.496644295302, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17562298, Length=301, Percent_Identity=26.2458471760797, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 33626; Mature: 33495

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIKTSFLKNGEREYKYLSLGNGKKLIFFFHGFPDDAGSMKELMQIFSKKDFTCIAPFM
CCHHHHHHHHCCCCCEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEHHHH
RGYSPGSSVPFSGTVSIAELAGDLKFIVESLKSVYNPETTIVLGHDWGAIASYAFSNLSP
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCC
GIIDTLVALSVPPIPTYLKNLLVYPSQIVRSWYILFFQIRAGIPEAALLKNDLLRRLWED
HHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
WSPGWKIPEERFREVFENLKVHENLITALGYYRGLLTPGNFALWNSSRELVFHKISVPTL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCCEE
ILAGEKDECISTSVYKGLESEFYSRVSFQVIDKAGHFLHLEAPERVAKEIFRFIKL
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEIKTSFLKNGEREYKYLSLGNGKKLIFFFHGFPDDAGSMKELMQIFSKKDFTCIAPFM
CHHHHHHHHCCCCCEEEEEECCCCEEEEEEECCCCCCHHHHHHHHHHCCCCCEEEHHHH
RGYSPGSSVPFSGTVSIAELAGDLKFIVESLKSVYNPETTIVLGHDWGAIASYAFSNLSP
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCC
GIIDTLVALSVPPIPTYLKNLLVYPSQIVRSWYILFFQIRAGIPEAALLKNDLLRRLWED
HHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
WSPGWKIPEERFREVFENLKVHENLITALGYYRGLLTPGNFALWNSSRELVFHKISVPTL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCCEE
ILAGEKDECISTSVYKGLESEFYSRVSFQVIDKAGHFLHLEAPERVAKEIFRFIKL
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]