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The map label for this gene is flhF

Identifier: 45657255

GI number: 45657255

Start: 1694979

End: 1696265

Strand: Direct

Name: flhF

Synonym: LIC11377

Alternate gene names: 45657255

Gene position: 1694979-1696265 (Clockwise)

Preceding gene: 45657254

Following gene: 45657256

Centisome position: 39.63

GC content: 38.46

Gene sequence:

>1287_bases
TTGAATATGGAGTTTGCTAAAATTCGGGGCAAAAGTTATCAAGATTGTTTGATGGAAATGAAAATGAAATACGGTTCTGA
AGCTACTGTAATTTCTCAAACGGTCGTAACCGAAGGTGGTGTGATGGGAACCGGGCTTCTTGCAAAAAAGATGATCGAAA
TACAAATTGGAATCCCAGAGAAACAAGCGTCTCGAGAAAAGATAGAACGTAAACTGCAAGACTTAAAGGATCTTTTAAAA
CAAAAATCTTATGCTTCACCGGAAAGAAAAAAAACTCTACAAACTTTAAAACCTCTTTCTAAAACTTTAGAAGAAAAAGA
AATTGCAGTCGAAGAGGAAATAGAAGAAATCACTACTGAGCCGGACAGAGTGGGTCTCTCTTTTGAAAAAGAACTTTTAG
ATAAAAATTCTTTTTTAAGAAGAGAAACTTCTACTGTTCGAAAGGATTCCCCCTTAATCCGATTGGGAGAAAAATTAGTT
CGAGAAGGAATGAGTCAGTCTTATGTGGAGGAGATTATTTCTAAAGTAGAAGAAAGACTTTCACCTCTAGATCAAGGACG
TAATCACGCCGTTTTAGAAAGGACAATTGAAATCTTAAAAGAAAGAGTGAGTGTGGACTCAGACCTTTTTCGGGGAACCG
GAAAAAATCAAAGAAAAGTGATCTTTTTTGTAGGACCTACTGGTTCCGGTAAAACTACAAGTGTGGCAAAACTTGCCGCA
AAATACTTTTTACACCGAGGTAAATCGGTTTCTCTTTATACTACGGACAATTATAGAATTGCTGCCATTGAACAACTCAA
ACGTTACGCAGATACGATGGGAATGCCGTTTTATCCGGTTAAAGACATAAAAAAATTCAAGGAAACCCTGGCTCGGGATG
GTTCCGAGCTCATTCTAATCGATACTGCGGGGTATAGTCATAGAAATTTAGAACAACTAGAAAGGATGAATAGTCTGCTT
TCTTGTTTTGGAGAAAAAGACTCTGTGGAAAATCTACTTGTCCTTTCGTCCACTTCTTCCTACCATCATACGAGCACTGT
ATTGAAAGCCTATGAGTCTTTAAATTACCGAAGAATTCTACTCACAAAACTAGATGAGGCGGATTTTTTAGGTGGTTTTC
TCGAACTGGCCGATACATACTCTAAGAGTTTCACATACTACAGCGTAGGTCAGGAAGTTCCCTTTGACATTCTTTCTGCC
GAAAAAAATCTTATGGCTGAATGTGTGGTAACTCCGGAGAAAATTGCTGAGCTGAGAGGAGAGGTTTTCACCGTTGCGGG
TGACTGA

Upstream 100 bases:

>100_bases
GCTGAGCTCAAACTTCCCCAGGCGCAGACTGCCGGAATTTCGGAAGAAACATGAAATACTTAGAATATTCTAATTTTATA
AAGTGGAATAATTAGAGGAG

Downstream 100 bases:

>100_bases
TTCGATCGGCTTTTGAAGAGGTAAAGAATGGATCAGGCGGCTCATTTACGGAAACTCACCGAGGGAAATACGAGTCTTAA
AGTTCTGTCATCCAGAAAAC

Product: flagellar biosynthesis regulator FlhF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MNMEFAKIRGKSYQDCLMEMKMKYGSEATVISQTVVTEGGVMGTGLLAKKMIEIQIGIPEKQASREKIERKLQDLKDLLK
QKSYASPERKKTLQTLKPLSKTLEEKEIAVEEEIEEITTEPDRVGLSFEKELLDKNSFLRRETSTVRKDSPLIRLGEKLV
REGMSQSYVEEIISKVEERLSPLDQGRNHAVLERTIEILKERVSVDSDLFRGTGKNQRKVIFFVGPTGSGKTTSVAKLAA
KYFLHRGKSVSLYTTDNYRIAAIEQLKRYADTMGMPFYPVKDIKKFKETLARDGSELILIDTAGYSHRNLEQLERMNSLL
SCFGEKDSVENLLVLSSTSSYHHTSTVLKAYESLNYRRILLTKLDEADFLGGFLELADTYSKSFTYYSVGQEVPFDILSA
EKNLMAECVVTPEKIAELRGEVFTVAGD

Sequences:

>Translated_428_residues
MNMEFAKIRGKSYQDCLMEMKMKYGSEATVISQTVVTEGGVMGTGLLAKKMIEIQIGIPEKQASREKIERKLQDLKDLLK
QKSYASPERKKTLQTLKPLSKTLEEKEIAVEEEIEEITTEPDRVGLSFEKELLDKNSFLRRETSTVRKDSPLIRLGEKLV
REGMSQSYVEEIISKVEERLSPLDQGRNHAVLERTIEILKERVSVDSDLFRGTGKNQRKVIFFVGPTGSGKTTSVAKLAA
KYFLHRGKSVSLYTTDNYRIAAIEQLKRYADTMGMPFYPVKDIKKFKETLARDGSELILIDTAGYSHRNLEQLERMNSLL
SCFGEKDSVENLLVLSSTSSYHHTSTVLKAYESLNYRRILLTKLDEADFLGGFLELADTYSKSFTYYSVGQEVPFDILSA
EKNLMAECVVTPEKIAELRGEVFTVAGD
>Mature_428_residues
MNMEFAKIRGKSYQDCLMEMKMKYGSEATVISQTVVTEGGVMGTGLLAKKMIEIQIGIPEKQASREKIERKLQDLKDLLK
QKSYASPERKKTLQTLKPLSKTLEEKEIAVEEEIEEITTEPDRVGLSFEKELLDKNSFLRRETSTVRKDSPLIRLGEKLV
REGMSQSYVEEIISKVEERLSPLDQGRNHAVLERTIEILKERVSVDSDLFRGTGKNQRKVIFFVGPTGSGKTTSVAKLAA
KYFLHRGKSVSLYTTDNYRIAAIEQLKRYADTMGMPFYPVKDIKKFKETLARDGSELILIDTAGYSHRNLEQLERMNSLL
SCFGEKDSVENLLVLSSTSSYHHTSTVLKAYESLNYRRILLTKLDEADFLGGFLELADTYSKSFTYYSVGQEVPFDILSA
EKNLMAECVVTPEKIAELRGEVFTVAGD

Specific function: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum [H]

COG id: COG1419

COG function: function code N; Flagellar GTP-binding protein

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=234, Percent_Identity=25.6410256410256, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI226371618, Length=234, Percent_Identity=25.6410256410256, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI1789874, Length=198, Percent_Identity=28.7878787878788, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788963, Length=188, Percent_Identity=26.5957446808511, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17539958, Length=187, Percent_Identity=26.7379679144385, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6325345, Length=192, Percent_Identity=29.6875, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17647949, Length=193, Percent_Identity=26.9430051813472, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR020006 [H]

Pfam domain/function: PF00448 SRP54 [H]

EC number: NA

Molecular weight: Translated: 48492; Mature: 48492

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMEFAKIRGKSYQDCLMEMKMKYGSEATVISQTVVTEGGVMGTGLLAKKMIEIQIGIPE
CCCCHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHEEEEECCCH
KQASREKIERKLQDLKDLLKQKSYASPERKKTLQTLKPLSKTLEEKEIAVEEEIEEITTE
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PDRVGLSFEKELLDKNSFLRRETSTVRKDSPLIRLGEKLVREGMSQSYVEEIISKVEERL
CHHCCCHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
SPLDQGRNHAVLERTIEILKERVSVDSDLFRGTGKNQRKVIFFVGPTGSGKTTSVAKLAA
HHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHH
KYFLHRGKSVSLYTTDNYRIAAIEQLKRYADTMGMPFYPVKDIKKFKETLARDGSELILI
HHHHHCCCEEEEEECCCEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEE
DTAGYSHRNLEQLERMNSLLSCFGEKDSVENLLVLSSTSSYHHTSTVLKAYESLNYRRIL
ECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEE
LTKLDEADFLGGFLELADTYSKSFTYYSVGQEVPFDILSAEKNLMAECVVTPEKIAELRG
EECCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCC
EVFTVAGD
CEEEEECC
>Mature Secondary Structure
MNMEFAKIRGKSYQDCLMEMKMKYGSEATVISQTVVTEGGVMGTGLLAKKMIEIQIGIPE
CCCCHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHEEEEECCCH
KQASREKIERKLQDLKDLLKQKSYASPERKKTLQTLKPLSKTLEEKEIAVEEEIEEITTE
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PDRVGLSFEKELLDKNSFLRRETSTVRKDSPLIRLGEKLVREGMSQSYVEEIISKVEERL
CHHCCCHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
SPLDQGRNHAVLERTIEILKERVSVDSDLFRGTGKNQRKVIFFVGPTGSGKTTSVAKLAA
HHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHHH
KYFLHRGKSVSLYTTDNYRIAAIEQLKRYADTMGMPFYPVKDIKKFKETLARDGSELILI
HHHHHCCCEEEEEECCCEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEEEE
DTAGYSHRNLEQLERMNSLLSCFGEKDSVENLLVLSSTSSYHHTSTVLKAYESLNYRRIL
ECCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCEEEE
LTKLDEADFLGGFLELADTYSKSFTYYSVGQEVPFDILSAEKNLMAECVVTPEKIAELRG
EECCCCHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHCC
EVFTVAGD
CEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]