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The map label for this gene is ygcM [C]

Identifier: 45657149

GI number: 45657149

Start: 1563574

End: 1563984

Strand: Direct

Name: ygcM [C]

Synonym: LIC11266

Alternate gene names: 45657149

Gene position: 1563574-1563984 (Clockwise)

Preceding gene: 45657146

Following gene: 45657156

Centisome position: 36.56

GC content: 35.52

Gene sequence:

>411_bases
ATGTTTTTTCAAGAATCAGGAAGATTTTATATTCGAATCGAGGAGCGTTTTGAATCCTCACATTATCTCTACAAATATTT
TCCAGATGGATCGGATGAACCGATCCATGGACATTCTTGGAAGGTAGAACTTTATCTTTCAGGAAAAAAAAATATCGGGG
ACGATGGAATCAGTTTTGATTTTCTCACTTCCAAACAAAAACTCAAAGAACTTGTAGGAAGGTTAGATCATATTCTAATT
AACGATTTAGAAGAGTTTAAAAAAATCAATCCTACTTCCGAAAACATTGCAAGATGGTTTTATCATTATCTCAAAGAAAG
TGTACATACTGCAGGGGGAAAAGTGGATCGAATTGTCATTCATGAAGGTCCCGAAAACCTCGCCTTTTTTGAGCCAACAT
CGCTTTCGTAA

Upstream 100 bases:

>100_bases
GGGATATTTTATTTCTGCAAGTTGCGAGAAACGTTTTTCCTCGGAAACAAAATTAACTCGGAATTCCAGTATATAGACGT
GGGAAAGAAAGTCAAGATCT

Downstream 100 bases:

>100_bases
AAAGCGATGTTGCAAAAAGACAAGCGTAGCGTAGTCTTTTGCTTTCAACGGAGTTGTAAAAATCATCGCTTTCGTAAAAA
GTGATGTTGCAAAAAGACAG

Product: putative 6-pyruvoyl tetrahydrobiopterin synthase

Products: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; CMP

Alternate protein names: 6-Pyruvoyl Tetrahydrobiopterin Synthase; 6-Pyruvoyl-Tetrahydropterin Synthase; Queuosine Biosynthesis Protein QueD; 6-Pyruvoyl Tetrahydrobiopterin Synthase Family Protein; Preq(0) Biosynthesis Protein Qued; 6-Carboxy-5 6 7 8-Tetrahydropterin Synthase; 6-Pyruvoyltetrahydropterin Synthase; 6-Pyruvoyl Tetrahydrobiopterin Synthase-Like Protein; 6-Pyruvoyl Tetrahydropterin Synthase Superfamily; Queuosine Biosynthesis Protein

Number of amino acids: Translated: 136; Mature: 136

Protein sequence:

>136_residues
MFFQESGRFYIRIEERFESSHYLYKYFPDGSDEPIHGHSWKVELYLSGKKNIGDDGISFDFLTSKQKLKELVGRLDHILI
NDLEEFKKINPTSENIARWFYHYLKESVHTAGGKVDRIVIHEGPENLAFFEPTSLS

Sequences:

>Translated_136_residues
MFFQESGRFYIRIEERFESSHYLYKYFPDGSDEPIHGHSWKVELYLSGKKNIGDDGISFDFLTSKQKLKELVGRLDHILI
NDLEEFKKINPTSENIARWFYHYLKESVHTAGGKVDRIVIHEGPENLAFFEPTSLS
>Mature_136_residues
MFFQESGRFYIRIEERFESSHYLYKYFPDGSDEPIHGHSWKVELYLSGKKNIGDDGISFDFLTSKQKLKELVGRLDHILI
NDLEEFKKINPTSENIARWFYHYLKESVHTAGGKVDRIVIHEGPENLAFFEPTSLS

Specific function: Tetrahydrobiopterin biosynthesis; second step. [C]

COG id: COG0720

COG function: function code H; 6-pyruvoyl-tetrahydropterin synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.6.1.12

Molecular weight: Translated: 15962; Mature: 15962

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFQESGRFYIRIEERFESSHYLYKYFPDGSDEPIHGHSWKVELYLSGKKNIGDDGISFD
CCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEH
FLTSKQKLKELVGRLDHILINDLEEFKKINPTSENIARWFYHYLKESVHTAGGKVDRIVI
HCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEE
HEGPENLAFFEPTSLS
ECCCCCCEEECCCCCC
>Mature Secondary Structure
MFFQESGRFYIRIEERFESSHYLYKYFPDGSDEPIHGHSWKVELYLSGKKNIGDDGISFD
CCCCCCCCEEEEEECCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEH
FLTSKQKLKELVGRLDHILINDLEEFKKINPTSENIARWFYHYLKESVHTAGGKVDRIVI
HCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEE
HEGPENLAFFEPTSLS
ECCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol

Specific reaction: 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + CMP

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA