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The map label for this gene is cya [H]

Identifier: 45657082

GI number: 45657082

Start: 1473693

End: 1474964

Strand: Direct

Name: cya [H]

Synonym: LIC11198

Alternate gene names: 45657082

Gene position: 1473693-1474964 (Clockwise)

Preceding gene: 45657081

Following gene: 45657083

Centisome position: 34.45

GC content: 39.47

Gene sequence:

>1272_bases
GTGTCCGATAATCAAGATGTTGAGGATTTTAAAAAACAATTCGTAGAGAACCAGAAAGGAATCGAGGAACTCAATCAGAA
ACTTCATCGAAAAACAAGAGAAGTAGAGATCATTCAGTCCATTTCGGCGGAGATTCTCAATACTCTTGATTTGGAGCAAA
TCTTTGAACGAATCATGGAGGTGATGGATGAAGTTTTTGGCTTCAAACACGCTATGATTCTGATGCTGGAAGAAGGCACG
GAGACTTTGAGTGTAAAGGCGAGCCGTGGATACGAACAAGGTGGTGTGGGAGCCAAGGTTGAATTCGGCCAAGGTGTGAT
CGGTGTGGTCGCTAAAAGAAAAAAAATCATGCGTATGGTCGGAATTACGACTCAGATGCGTTATGCGGGACAGATCGGTC
AATCCATGGGAAGAGAAGAAAAACAAATAGAACTTCCCGGTTTGAAAGATGCAAAAAGTCAAATCGCAATTCCACTGCTT
GTCAAAGACAAGTTACTCGGAGTTTTTGCAGTGGAAAGTGCAGAGATGAATGCTTTTAAACTTTTAGACGAAGTAATTTT
AAGCGTAGTCGGGAATCAGATTGCGGTAGCCATTGAAAACGCAGCAGCGTATTACACACAACAACAATTGTCGGAAGCTT
ACAGTCGATTTGTACCTAAGGAACTTCTTTCTCTTCTGAGTAAAAAATCGATTTTAGAGACCCAATTGGCTGATCAAACA
GAAGGTTTGATGACTGTGATGTTTTCGGATATCCGCGGTTTTACTACAATTTCCGAAAAGATGACCCCGAGTGAAAACTT
TCAGTTTATCAATAACTATTTGGGAATGATTGCTCCTGTAATTAAAGAACATAACGGTTTTATTGATAAGTTTATTGGGG
ATGCGATTATGGCTATTTTTCCCGCTCGCGCAGAAAACGCAGTAGAAGCGGCTTTAGCAATGATGAAAGCGCTTCAACAA
TTCAATGAACTTAGACAGAAAGAAAATCAAGATCCAATTGATATTGGTATAGGAATTCATACGGGTCATTTGATGCTCGG
AATTATAGGTCACGAAAATCGTATGGAAGGTACAGTGATCGGGGATAGTGTGAATCTTGCATCTAGAATTGAGGGTCTTA
CAAAACAATTCAAATGTTCGATCATTGTGAGTGAGGTTACGATTGCTTCTTTGAGAGATCCAAGCCGTTTTACACATTCT
TTTTTAGATGAAGTTACCGTAAAAGGAAAATCTCAACCTATTAAAGTCTATAAGATCGAAAATTCAGTATAA

Upstream 100 bases:

>100_bases
CGTCTATGTCCGGTATGAGTGACGTATTTAAACTCAAAGCGGCAGATATTTTCGAAATACGTTCCGTTCGGAAATTTACG
GAAGCTAAGGAGTCTTAATC

Downstream 100 bases:

>100_bases
CTTCGAACGACTTTTATAAGCTGAACTTAGAAGAGGAATTTTGAACTTAAAAGACGGTCCGATTTTTAAAAGTAAATGAT
TGGGTGAAAATAAATTTATA

Product: adenylate/guanylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase; Adenylyl cyclase [H]

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MSDNQDVEDFKKQFVENQKGIEELNQKLHRKTREVEIIQSISAEILNTLDLEQIFERIMEVMDEVFGFKHAMILMLEEGT
ETLSVKASRGYEQGGVGAKVEFGQGVIGVVAKRKKIMRMVGITTQMRYAGQIGQSMGREEKQIELPGLKDAKSQIAIPLL
VKDKLLGVFAVESAEMNAFKLLDEVILSVVGNQIAVAIENAAAYYTQQQLSEAYSRFVPKELLSLLSKKSILETQLADQT
EGLMTVMFSDIRGFTTISEKMTPSENFQFINNYLGMIAPVIKEHNGFIDKFIGDAIMAIFPARAENAVEAALAMMKALQQ
FNELRQKENQDPIDIGIGIHTGHLMLGIIGHENRMEGTVIGDSVNLASRIEGLTKQFKCSIIVSEVTIASLRDPSRFTHS
FLDEVTVKGKSQPIKVYKIENSV

Sequences:

>Translated_423_residues
MSDNQDVEDFKKQFVENQKGIEELNQKLHRKTREVEIIQSISAEILNTLDLEQIFERIMEVMDEVFGFKHAMILMLEEGT
ETLSVKASRGYEQGGVGAKVEFGQGVIGVVAKRKKIMRMVGITTQMRYAGQIGQSMGREEKQIELPGLKDAKSQIAIPLL
VKDKLLGVFAVESAEMNAFKLLDEVILSVVGNQIAVAIENAAAYYTQQQLSEAYSRFVPKELLSLLSKKSILETQLADQT
EGLMTVMFSDIRGFTTISEKMTPSENFQFINNYLGMIAPVIKEHNGFIDKFIGDAIMAIFPARAENAVEAALAMMKALQQ
FNELRQKENQDPIDIGIGIHTGHLMLGIIGHENRMEGTVIGDSVNLASRIEGLTKQFKCSIIVSEVTIASLRDPSRFTHS
FLDEVTVKGKSQPIKVYKIENSV
>Mature_422_residues
SDNQDVEDFKKQFVENQKGIEELNQKLHRKTREVEIIQSISAEILNTLDLEQIFERIMEVMDEVFGFKHAMILMLEEGTE
TLSVKASRGYEQGGVGAKVEFGQGVIGVVAKRKKIMRMVGITTQMRYAGQIGQSMGREEKQIELPGLKDAKSQIAIPLLV
KDKLLGVFAVESAEMNAFKLLDEVILSVVGNQIAVAIENAAAYYTQQQLSEAYSRFVPKELLSLLSKKSILETQLADQTE
GLMTVMFSDIRGFTTISEKMTPSENFQFINNYLGMIAPVIKEHNGFIDKFIGDAIMAIFPARAENAVEAALAMMKALQQF
NELRQKENQDPIDIGIGIHTGHLMLGIIGHENRMEGTVIGDSVNLASRIEGLTKQFKCSIIVSEVTIASLRDPSRFTHSF
LDEVTVKGKSQPIKVYKIENSV

Specific function: May function as a membrane-localized receptor protein [H]

COG id: COG2114

COG function: function code T; Adenylate cyclase, family 3 (some proteins contain HAMP domain)

Gene ontology:

Cell location: Cellular thylakoid membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

Organism=Homo sapiens, GI134152694, Length=187, Percent_Identity=28.8770053475936, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI167830411, Length=229, Percent_Identity=28.3842794759825, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI4580422, Length=229, Percent_Identity=27.5109170305677, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI222080083, Length=200, Percent_Identity=31, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI4504217, Length=187, Percent_Identity=27.807486631016, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17534659, Length=176, Percent_Identity=31.8181818181818, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193206632, Length=188, Percent_Identity=31.9148936170213, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17561804, Length=208, Percent_Identity=26.4423076923077, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17534649, Length=204, Percent_Identity=25.9803921568627, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24647268, Length=185, Percent_Identity=31.3513513513514, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI161076872, Length=175, Percent_Identity=26.8571428571429, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28574512, Length=175, Percent_Identity=26.8571428571429, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221330470, Length=178, Percent_Identity=32.5842696629214, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI221330468, Length=178, Percent_Identity=32.5842696629214, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00672 HAMP [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 47158; Mature: 47027

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS50125 GUANYLATE_CYCLASES_2 ; PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDNQDVEDFKKQFVENQKGIEELNQKLHRKTREVEIIQSISAEILNTLDLEQIFERIME
CCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VMDEVFGFKHAMILMLEEGTETLSVKASRGYEQGGVGAKVEFGQGVIGVVAKRKKIMRMV
HHHHHHCCHHEEEEEEECCCCEEEEECCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHH
GITTQMRYAGQIGQSMGREEKQIELPGLKDAKSQIAIPLLVKDKLLGVFAVESAEMNAFK
HHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHCCEEEEEEHHHHHHHEEECCCCHHHHH
LLDEVILSVVGNQIAVAIENAAAYYTQQQLSEAYSRFVPKELLSLLSKKSILETQLADQT
HHHHHHHHHHCCHHEEEEHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
EGLMTVMFSDIRGFTTISEKMTPSENFQFINNYLGMIAPVIKEHNGFIDKFIGDAIMAIF
HHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
PARAENAVEAALAMMKALQQFNELRQKENQDPIDIGIGIHTGHLMLGIIGHENRMEGTVI
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCEEEEEECCCCCCCCEEE
GDSVNLASRIEGLTKQFKCSIIVSEVTIASLRDPSRFTHSFLDEVTVKGKSQPIKVYKIE
CCCCCHHHHHHHHHHHHHHEEEEHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEEC
NSV
CCC
>Mature Secondary Structure 
SDNQDVEDFKKQFVENQKGIEELNQKLHRKTREVEIIQSISAEILNTLDLEQIFERIME
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VMDEVFGFKHAMILMLEEGTETLSVKASRGYEQGGVGAKVEFGQGVIGVVAKRKKIMRMV
HHHHHHCCHHEEEEEEECCCCEEEEECCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHH
GITTQMRYAGQIGQSMGREEKQIELPGLKDAKSQIAIPLLVKDKLLGVFAVESAEMNAFK
HHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHCCEEEEEEHHHHHHHEEECCCCHHHHH
LLDEVILSVVGNQIAVAIENAAAYYTQQQLSEAYSRFVPKELLSLLSKKSILETQLADQT
HHHHHHHHHHCCHHEEEEHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
EGLMTVMFSDIRGFTTISEKMTPSENFQFINNYLGMIAPVIKEHNGFIDKFIGDAIMAIF
HHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
PARAENAVEAALAMMKALQQFNELRQKENQDPIDIGIGIHTGHLMLGIIGHENRMEGTVI
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCEEEEEECCCCCCCCEEE
GDSVNLASRIEGLTKQFKCSIIVSEVTIASLRDPSRFTHSFLDEVTVKGKSQPIKVYKIE
CCCCCHHHHHHHHHHHHHHEEEEHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEEC
NSV
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7601856 [H]