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The map label for this gene is malZ

Identifier: 45657001

GI number: 45657001

Start: 1378405

End: 1380564

Strand: Direct

Name: malZ

Synonym: LIC11117

Alternate gene names: 45657001

Gene position: 1378405-1380564 (Clockwise)

Preceding gene: 45657000

Following gene: 45657002

Centisome position: 32.23

GC content: 36.39

Gene sequence:

>2160_bases
ATGTTTTTTCAACGTGTGATTTTGGCGTTTATTTTTTCGAGTTTTTTATCTTGTTCCGGACCTTTTGCAGATTACACAAA
AATAGATCTTCCTTCTAAAAAACAATTTTCCTTCGGTAAAAACTTTCAAGCAATCCAAAAAGAAAACGTTTTAGAAATAC
GTTCCGTTGCGGGAACTTTTTTAGAACTTTCTATGGTGAAACCTTTTTTATCCGCGGCAAAGGGAGAACAGGAAGTGAAA
TATAAATTCGCTTCTTTTCATATTAAAGATAAAATTATATTTCGATGTGATTTTCAGAGTATTGAAACTATGATTTCTTC
CTTGAACGATTTTAAAATTTCAGGAATTTTAGAAGGAAAAGGTTGTAGAAGCAAGTATGAAATCGTTTTTATACCGTTAG
ACGAAATATCAATTCGATTTAAGATAAAGATCGAAGACGTTTCTTTAAATCGTTCTTACTTTAGAATGGTTTCGGATGAA
ACCGAAAATATTTTTGGGCTTGGGGAACAGTTCAGTCATTTTAATCTAAAAGGTAAAACACCTTTTTTATTTACGGAAGA
ACAAGGAGTTGGAAGGGGGGATCAACCGATCACTACAGGGGCTAACCTTCTTGCGGATGCGGGTGGAAACGAATATACTA
CTTACGCTCCGATTCCATTTTTTCTGACTTCCAAAAACAGATCCGTTTATTTTGAAAATTCATCTTATTCAAAATTTGAT
TTTTCTAATTCGGAGGAAATTTTAGTAGAGTTTAGAGAAAATGGTCTTCAAGGAATCATTTGGAAAGATTCTTCTCCAAT
CAAACTTGTGCAAAAGTTTACTGAAAAAACTGGAAGGACACCGGAACTTCCGGACTGGGCCTATGGAACTTGGTTGGGAA
TACAAGGTGGAAAAGAAAAAGTTCTAAAACAAATCGAGGCCGCCAGAAAAGAAGGAAACCCGATTACGGCGCTTTGGATT
CAAGATTGGGTTGGAAGAAGAAAAACTAGTTTCGGGTCTCAGTTGTGGTGGAGATGGATCGCGGACGAAAAGTTTTATCC
GGAATTTAAAAATTTTTGTTCCGATTTAAACAAACAAGGAATTCATGTATTAGGATATTTGAATCCTTTTTTAGCAACAG
AAGGACCGCTCTACGAAGAAGCTGTACAAAAAGGATATTTAATAAAAGATAAAAACGGAAATAATTACGTAATTGAAACC
GTAGGTTTTCCTGCGGTTCTTTTAGATTTGACTCACCCGGAAGCGGTGAAATGGATTCAAAAAATCATTCAAAAAAATCT
AATCGGAGTCGGGCTTTCCGGATGGATGGCTGATTTTGGAGAATGGCTTCCTTTAGACGCAAGTTTGTATTCCGGAATTT
CTGCAGATGTTTATCATAACGTGTATCCGGTCGAATGGGCTCGGATCAATAGAGAAGCGATTCGAAATGTTGGAAAAGAA
GGTAAGATCGTATTCTTTACGAGATCTGGGTATAGTGGTTCGATGAAACATTCCACCCTTTTTTGGGAAGGGGATCAGAT
GGTCAGTTGGGGAGAACACGACGGAATTGTATCTGCTGTGACCGCACTTCTTTCTGGGGGATTGAGTGGAATTTCAATCA
ATCATAGTGATATAGGTGGATATACTACGATCAATAATCCGATCCGAAATTATCATAGGTCCAAAGAATTATTTTTACGT
TGGGCGGAATTGAATGTATTTAGTTCAGTGTTTCGAACTCACGAAGGAAACCGTCCCGAAAAAAATCATCAATCTTATTC
GGATGAAGAAACGATCCAAGAATTTGCCAGATATGGAAAGATGCACTTCGCATTAAAAGAGTATCTCAAATTTCTTATAA
AGGAAGCTTTTAAGACAGGACTTCCTGTTGTAAGACCACTTTACTTACATTATTCGATGGATCGAAAAACTCACGATCTC
AAAAGAGAATTTCTTTTAGGTGAAGACCTTTTAGTTTTTCCAGTTTTGGAGGAAGGGGAAATTTTCGTGTCTGGTTATCT
ACCAGAAGGAGAATGGGAACACGTTTGGACCGAGAAAATTTTTACTGGAAAAAACGAAGTAAAAGTGGAAGCTCCGTTAG
GCGCTCCTGCAATTTTTTTGAAAAAAAACGGAATCTGGTATTCTAAATTAAAAAATGCCCTTTATAAATTTAAAAAATAA

Upstream 100 bases:

>100_bases
TTGAACTGGGATTTTTCTGATCGTTTTAGAATTTTAGTTTGAACAAACTAAAAAACGGAATTCATTTAAAAATATCTTAT
CGGTTTATAAGGAAAATTGA

Downstream 100 bases:

>100_bases
ATCTTATAATTTTTCTTATTTATTTTTGAATGGTTAGGCACACTGAGGTGGTCTATAAAATAGAATGCAATCTGAAGTTT
TTAAAGATCCAATCGTATTT

Product: alpha-glucosidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 719; Mature: 719

Protein sequence:

>719_residues
MFFQRVILAFIFSSFLSCSGPFADYTKIDLPSKKQFSFGKNFQAIQKENVLEIRSVAGTFLELSMVKPFLSAAKGEQEVK
YKFASFHIKDKIIFRCDFQSIETMISSLNDFKISGILEGKGCRSKYEIVFIPLDEISIRFKIKIEDVSLNRSYFRMVSDE
TENIFGLGEQFSHFNLKGKTPFLFTEEQGVGRGDQPITTGANLLADAGGNEYTTYAPIPFFLTSKNRSVYFENSSYSKFD
FSNSEEILVEFRENGLQGIIWKDSSPIKLVQKFTEKTGRTPELPDWAYGTWLGIQGGKEKVLKQIEAARKEGNPITALWI
QDWVGRRKTSFGSQLWWRWIADEKFYPEFKNFCSDLNKQGIHVLGYLNPFLATEGPLYEEAVQKGYLIKDKNGNNYVIET
VGFPAVLLDLTHPEAVKWIQKIIQKNLIGVGLSGWMADFGEWLPLDASLYSGISADVYHNVYPVEWARINREAIRNVGKE
GKIVFFTRSGYSGSMKHSTLFWEGDQMVSWGEHDGIVSAVTALLSGGLSGISINHSDIGGYTTINNPIRNYHRSKELFLR
WAELNVFSSVFRTHEGNRPEKNHQSYSDEETIQEFARYGKMHFALKEYLKFLIKEAFKTGLPVVRPLYLHYSMDRKTHDL
KREFLLGEDLLVFPVLEEGEIFVSGYLPEGEWEHVWTEKIFTGKNEVKVEAPLGAPAIFLKKNGIWYSKLKNALYKFKK

Sequences:

>Translated_719_residues
MFFQRVILAFIFSSFLSCSGPFADYTKIDLPSKKQFSFGKNFQAIQKENVLEIRSVAGTFLELSMVKPFLSAAKGEQEVK
YKFASFHIKDKIIFRCDFQSIETMISSLNDFKISGILEGKGCRSKYEIVFIPLDEISIRFKIKIEDVSLNRSYFRMVSDE
TENIFGLGEQFSHFNLKGKTPFLFTEEQGVGRGDQPITTGANLLADAGGNEYTTYAPIPFFLTSKNRSVYFENSSYSKFD
FSNSEEILVEFRENGLQGIIWKDSSPIKLVQKFTEKTGRTPELPDWAYGTWLGIQGGKEKVLKQIEAARKEGNPITALWI
QDWVGRRKTSFGSQLWWRWIADEKFYPEFKNFCSDLNKQGIHVLGYLNPFLATEGPLYEEAVQKGYLIKDKNGNNYVIET
VGFPAVLLDLTHPEAVKWIQKIIQKNLIGVGLSGWMADFGEWLPLDASLYSGISADVYHNVYPVEWARINREAIRNVGKE
GKIVFFTRSGYSGSMKHSTLFWEGDQMVSWGEHDGIVSAVTALLSGGLSGISINHSDIGGYTTINNPIRNYHRSKELFLR
WAELNVFSSVFRTHEGNRPEKNHQSYSDEETIQEFARYGKMHFALKEYLKFLIKEAFKTGLPVVRPLYLHYSMDRKTHDL
KREFLLGEDLLVFPVLEEGEIFVSGYLPEGEWEHVWTEKIFTGKNEVKVEAPLGAPAIFLKKNGIWYSKLKNALYKFKK
>Mature_719_residues
MFFQRVILAFIFSSFLSCSGPFADYTKIDLPSKKQFSFGKNFQAIQKENVLEIRSVAGTFLELSMVKPFLSAAKGEQEVK
YKFASFHIKDKIIFRCDFQSIETMISSLNDFKISGILEGKGCRSKYEIVFIPLDEISIRFKIKIEDVSLNRSYFRMVSDE
TENIFGLGEQFSHFNLKGKTPFLFTEEQGVGRGDQPITTGANLLADAGGNEYTTYAPIPFFLTSKNRSVYFENSSYSKFD
FSNSEEILVEFRENGLQGIIWKDSSPIKLVQKFTEKTGRTPELPDWAYGTWLGIQGGKEKVLKQIEAARKEGNPITALWI
QDWVGRRKTSFGSQLWWRWIADEKFYPEFKNFCSDLNKQGIHVLGYLNPFLATEGPLYEEAVQKGYLIKDKNGNNYVIET
VGFPAVLLDLTHPEAVKWIQKIIQKNLIGVGLSGWMADFGEWLPLDASLYSGISADVYHNVYPVEWARINREAIRNVGKE
GKIVFFTRSGYSGSMKHSTLFWEGDQMVSWGEHDGIVSAVTALLSGGLSGISINHSDIGGYTTINNPIRNYHRSKELFLR
WAELNVFSSVFRTHEGNRPEKNHQSYSDEETIQEFARYGKMHFALKEYLKFLIKEAFKTGLPVVRPLYLHYSMDRKTHDL
KREFLLGEDLLVFPVLEEGEIFVSGYLPEGEWEHVWTEKIFTGKNEVKVEAPLGAPAIFLKKNGIWYSKLKNALYKFKK

Specific function: Exhibits hydrolysis activity against alpha-glucosyl fluoride, although natural substrates, such as alpha-glucobioses are scarcely hydrolyzed [H]

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI119393895, Length=531, Percent_Identity=22.9755178907721, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI119393893, Length=531, Percent_Identity=22.9755178907721, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI119393891, Length=531, Percent_Identity=22.9755178907721, Blast_Score=103, Evalue=5e-22,
Organism=Homo sapiens, GI221316699, Length=650, Percent_Identity=24.3076923076923, Blast_Score=103, Evalue=8e-22,
Organism=Homo sapiens, GI153791946, Length=419, Percent_Identity=24.582338902148, Blast_Score=94, Evalue=6e-19,
Organism=Homo sapiens, GI66346737, Length=433, Percent_Identity=24.0184757505774, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI88900491, Length=392, Percent_Identity=23.469387755102, Blast_Score=91, Evalue=5e-18,
Organism=Homo sapiens, GI38202257, Length=392, Percent_Identity=23.469387755102, Blast_Score=90, Evalue=7e-18,
Organism=Homo sapiens, GI157364974, Length=378, Percent_Identity=23.2804232804233, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI310115361, Length=237, Percent_Identity=28.2700421940928, Blast_Score=86, Evalue=1e-16,
Organism=Escherichia coli, GI2367323, Length=668, Percent_Identity=39.8203592814371, Blast_Score=494, Evalue=1e-141,
Organism=Escherichia coli, GI2367256, Length=569, Percent_Identity=22.6713532513181, Blast_Score=162, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI71991189, Length=481, Percent_Identity=23.0769230769231, Blast_Score=96, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17560798, Length=387, Percent_Identity=23.2558139534884, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17560800, Length=387, Percent_Identity=23.2558139534884, Blast_Score=87, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71985706, Length=242, Percent_Identity=26.8595041322314, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI32563849, Length=218, Percent_Identity=27.5229357798165, Blast_Score=77, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6319706, Length=514, Percent_Identity=20.2334630350195, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24650054, Length=369, Percent_Identity=28.7262872628726, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI28571440, Length=350, Percent_Identity=22.2857142857143, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28571438, Length=351, Percent_Identity=22.5071225071225, Blast_Score=73, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24643749, Length=503, Percent_Identity=20.675944333996, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24643753, Length=503, Percent_Identity=20.675944333996, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24643751, Length=503, Percent_Identity=20.675944333996, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24643746, Length=503, Percent_Identity=20.675944333996, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI21357605, Length=503, Percent_Identity=20.675944333996, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 82331; Mature: 82331

Theoretical pI: Translated: 8.00; Mature: 8.00

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFQRVILAFIFSSFLSCSGPFADYTKIDLPSKKQFSFGKNFQAIQKENVLEIRSVAGTF
CHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHH
LELSMVKPFLSAAKGEQEVKYKFASFHIKDKIIFRCDFQSIETMISSLNDFKISGILEGK
HHHHHHHHHHHHHCCCHHHEEEEEEEEEEEEEEEEECHHHHHHHHHCCCCEEEEEEEECC
GCRSKYEIVFIPLDEISIRFKIKIEDVSLNRSYFRMVSDETENIFGLGEQFSHFNLKGKT
CCCCCEEEEEEEECCEEEEEEEEEEEEECCHHHHHHHHCCCCHHHCCCCHHCCEECCCCC
PFLFTEEQGVGRGDQPITTGANLLADAGGNEYTTYAPIPFFLTSKNRSVYFENSSYSKFD
CEEEECCCCCCCCCCCCCCCCHHHCCCCCCCEEEECCCEEEEECCCCEEEEECCCCCCCC
FSNSEEILVEFRENGLQGIIWKDSSPIKLVQKFTEKTGRTPELPDWAYGTWLGIQGGKEK
CCCCHHHHHEEHHCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHH
VLKQIEAARKEGNPITALWIQDWVGRRKTSFGSQLWWRWIADEKFYPEFKNFCSDLNKQG
HHHHHHHHHHCCCCEEEEEEHHHHCCHHHCCCHHHHHHEECCCCCCHHHHHHHHHHCCCC
IHVLGYLNPFLATEGPLYEEAVQKGYLIKDKNGNNYVIETVGFPAVLLDLTHPEAVKWIQ
EEEEEECCHHHCCCCCHHHHHHHCCEEEEECCCCEEEEEECCCCEEEEECCCHHHHHHHH
KIIQKNLIGVGLSGWMADFGEWLPLDASLYSGISADVYHNVYPVEWARINREAIRNVGKE
HHHHHHHHCCCHHHHHHHHCCCCCCCHHHHCCCCHHHHCCCCCCHHHHCCHHHHHCCCCC
GKIVFFTRSGYSGSMKHSTLFWEGDQMVSWGEHDGIVSAVTALLSGGLSGISINHSDIGG
CCEEEEEECCCCCCCCCCEEEECCCCEECCCCCCCHHHHHHHHHHCCCCCEEECCCCCCC
YTTINNPIRNYHRSKELFLRWAELNVFSSVFRTHEGNRPEKNHQSYSDEETIQEFARYGK
EEECCCHHHHHHCCHHHHEEHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCH
MHFALKEYLKFLIKEAFKTGLPVVRPLYLHYSMDRKTHDLKREFLLGEDLLVFPVLEEGE
HHHHHHHHHHHHHHHHHHCCCCHHEEEEEEEECCCHHHHHHHHHHCCCCEEEEEEECCCC
IFVSGYLPEGEWEHVWTEKIFTGKNEVKVEAPLGAPAIFLKKNGIWYSKLKNALYKFKK
EEEEEECCCCCCCHHHHHHHCCCCCCEEEECCCCCCEEEEEECCEEHHHHHHHHHHCCC
>Mature Secondary Structure
MFFQRVILAFIFSSFLSCSGPFADYTKIDLPSKKQFSFGKNFQAIQKENVLEIRSVAGTF
CHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHH
LELSMVKPFLSAAKGEQEVKYKFASFHIKDKIIFRCDFQSIETMISSLNDFKISGILEGK
HHHHHHHHHHHHHCCCHHHEEEEEEEEEEEEEEEEECHHHHHHHHHCCCCEEEEEEEECC
GCRSKYEIVFIPLDEISIRFKIKIEDVSLNRSYFRMVSDETENIFGLGEQFSHFNLKGKT
CCCCCEEEEEEEECCEEEEEEEEEEEEECCHHHHHHHHCCCCHHHCCCCHHCCEECCCCC
PFLFTEEQGVGRGDQPITTGANLLADAGGNEYTTYAPIPFFLTSKNRSVYFENSSYSKFD
CEEEECCCCCCCCCCCCCCCCHHHCCCCCCCEEEECCCEEEEECCCCEEEEECCCCCCCC
FSNSEEILVEFRENGLQGIIWKDSSPIKLVQKFTEKTGRTPELPDWAYGTWLGIQGGKEK
CCCCHHHHHEEHHCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCHHH
VLKQIEAARKEGNPITALWIQDWVGRRKTSFGSQLWWRWIADEKFYPEFKNFCSDLNKQG
HHHHHHHHHHCCCCEEEEEEHHHHCCHHHCCCHHHHHHEECCCCCCHHHHHHHHHHCCCC
IHVLGYLNPFLATEGPLYEEAVQKGYLIKDKNGNNYVIETVGFPAVLLDLTHPEAVKWIQ
EEEEEECCHHHCCCCCHHHHHHHCCEEEEECCCCEEEEEECCCCEEEEECCCHHHHHHHH
KIIQKNLIGVGLSGWMADFGEWLPLDASLYSGISADVYHNVYPVEWARINREAIRNVGKE
HHHHHHHHCCCHHHHHHHHCCCCCCCHHHHCCCCHHHHCCCCCCHHHHCCHHHHHCCCCC
GKIVFFTRSGYSGSMKHSTLFWEGDQMVSWGEHDGIVSAVTALLSGGLSGISINHSDIGG
CCEEEEEECCCCCCCCCCEEEECCCCEECCCCCCCHHHHHHHHHHCCCCCEEECCCCCCC
YTTINNPIRNYHRSKELFLRWAELNVFSSVFRTHEGNRPEKNHQSYSDEETIQEFARYGK
EEECCCHHHHHHCCHHHHEEHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCH
MHFALKEYLKFLIKEAFKTGLPVVRPLYLHYSMDRKTHDLKREFLLGEDLLVFPVLEEGE
HHHHHHHHHHHHHHHHHHCCCCHHEEEEEEEECCCHHHHHHHHHHCCCCEEEEEEECCCC
IFVSGYLPEGEWEHVWTEKIFTGKNEVKVEAPLGAPAIFLKKNGIWYSKLKNALYKFKK
EEEEEECCCCCCCHHHHHHHCCCCCCEEEECCCCCCEEEEEECCEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503 [H]