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The map label for this gene is kdpE

Identifier: 45656882

GI number: 45656882

Start: 1210408

End: 1211091

Strand: Direct

Name: kdpE

Synonym: LIC10994

Alternate gene names: 45656882

Gene position: 1210408-1211091 (Clockwise)

Preceding gene: 45656881

Following gene: 45656884

Centisome position: 28.3

GC content: 39.04

Gene sequence:

>684_bases
ATGAATCCTAAAATTCTGGTGGCGGATGATGACGATCGTATTCGCAAGATGATACGAATCAGTTTGAACGCTTCTCATTA
CGAAGTGATTGAGTCTGCTACAATTCAAGAAACGATACTCAAAGCCGCGAAAAATTCTCCGGATTTGATTTTATTAGACT
TACAATTTCCAGATGGTAACGGGATTACTGCATTGAGGGAGATACGATCTTGGAGCGAAACTCCGGTGATCGTATTGTCA
GTTCTTGCTTCCGATCCTGAAAAAATTTCACTGTTAGATGGAGGGGCCGACGACTATATTACAAAACCATTTAGTATGGG
AGAGTTATTGGCAAGAATTCGGGTTGCTCTTAGAAATAAGACTCAAGATCCAGGGTCTCCTATTTTTATATCTGGAAATT
TATATGTAGATTTATCAAATAGAAACGTAAAAGTATCCGGAATCACGGTACATTTGACTCCGACCGAATATATATTTTTG
ACCTTTTTAATTCAACACGCAGGAAAGGTATTAACACAGGAACAGATTATACGTCACGTTTGGGGGCCTTTTGCAAAAAA
CGAATCCGGGTCTTTGAGAGTTCACGTAGCAAGTTTAAGAAAAAAAATAGAATTGGATCCCTCCAGTCCAGAGTTACTTT
TGACGGAGCCAGGGGTAGGTTATAGGCTTGCAATTCATTTATAA

Upstream 100 bases:

>100_bases
ATCTATTGTGGAAACACACGGAGGTACTTTAACCGCAGAAAATAGAATAATAGTAGGGGCCAGGTTTTGTATCGAAATTC
CGATCAAATCGAGTTAAAAA

Downstream 100 bases:

>100_bases
TATTCAATTTACATCATGTAATATAAGTTAAGTGAAAATTACAAGACGCTACTCGAAGTTATATAGTAAATACCTGTTCG
GAGTTGTATAACAGAGTGCT

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MNPKILVADDDDRIRKMIRISLNASHYEVIESATIQETILKAAKNSPDLILLDLQFPDGNGITALREIRSWSETPVIVLS
VLASDPEKISLLDGGADDYITKPFSMGELLARIRVALRNKTQDPGSPIFISGNLYVDLSNRNVKVSGITVHLTPTEYIFL
TFLIQHAGKVLTQEQIIRHVWGPFAKNESGSLRVHVASLRKKIELDPSSPELLLTEPGVGYRLAIHL

Sequences:

>Translated_227_residues
MNPKILVADDDDRIRKMIRISLNASHYEVIESATIQETILKAAKNSPDLILLDLQFPDGNGITALREIRSWSETPVIVLS
VLASDPEKISLLDGGADDYITKPFSMGELLARIRVALRNKTQDPGSPIFISGNLYVDLSNRNVKVSGITVHLTPTEYIFL
TFLIQHAGKVLTQEQIIRHVWGPFAKNESGSLRVHVASLRKKIELDPSSPELLLTEPGVGYRLAIHL
>Mature_227_residues
MNPKILVADDDDRIRKMIRISLNASHYEVIESATIQETILKAAKNSPDLILLDLQFPDGNGITALREIRSWSETPVIVLS
VLASDPEKISLLDGGADDYITKPFSMGELLARIRVALRNKTQDPGSPIFISGNLYVDLSNRNVKVSGITVHLTPTEYIFL
TFLIQHAGKVLTQEQIIRHVWGPFAKNESGSLRVHVASLRKKIELDPSSPELLLTEPGVGYRLAIHL

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=44.5945945945946, Blast_Score=204, Evalue=4e-54,
Organism=Escherichia coli, GI1786599, Length=231, Percent_Identity=31.6017316017316, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=33.1838565022422, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=29.3859649122807, Blast_Score=114, Evalue=5e-27,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=31.7180616740088, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=32.1100917431193, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787375, Length=219, Percent_Identity=29.2237442922374, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=33.1838565022422, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=33.6244541484716, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=30.4932735426009, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=25.974025974026, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790860, Length=187, Percent_Identity=29.9465240641711, Blast_Score=84, Evalue=5e-18,
Organism=Escherichia coli, GI1787229, Length=187, Percent_Identity=29.9465240641711, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI145693140, Length=237, Percent_Identity=26.5822784810127, Blast_Score=76, Evalue=1e-15,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=32.7586206896552, Blast_Score=71, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25198; Mature: 25198

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPKILVADDDDRIRKMIRISLNASHYEVIESATIQETILKAAKNSPDLILLDLQFPDGN
CCCCEEEECCHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCC
GITALREIRSWSETPVIVLSVLASDPEKISLLDGGADDYITKPFSMGELLARIRVALRNK
CHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCC
TQDPGSPIFISGNLYVDLSNRNVKVSGITVHLTPTEYIFLTFLIQHAGKVLTQEQIIRHV
CCCCCCCEEEECEEEEEECCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
WGPFAKNESGSLRVHVASLRKKIELDPSSPELLLTEPGVGYRLAIHL
CCCCCCCCCCCEEEEEEHHHHEEECCCCCCCEEEECCCCCEEEEEEC
>Mature Secondary Structure
MNPKILVADDDDRIRKMIRISLNASHYEVIESATIQETILKAAKNSPDLILLDLQFPDGN
CCCCEEEECCHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCC
GITALREIRSWSETPVIVLSVLASDPEKISLLDGGADDYITKPFSMGELLARIRVALRNK
CHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCC
TQDPGSPIFISGNLYVDLSNRNVKVSGITVHLTPTEYIFLTFLIQHAGKVLTQEQIIRHV
CCCCCCCEEEECEEEEEECCCEEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
WGPFAKNESGSLRVHVASLRKKIELDPSSPELLLTEPGVGYRLAIHL
CCCCCCCCCCCEEEEEEHHHHEEECCCCCCCEEEECCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]