Click here to switch to the map view.

The map label for this gene is frc [H]

Identifier: 45656857

GI number: 45656857

Start: 1168252

End: 1169424

Strand: Direct

Name: frc [H]

Synonym: LIC10969

Alternate gene names: 45656857

Gene position: 1168252-1169424 (Clockwise)

Preceding gene: 45656855

Following gene: 45656858

Centisome position: 27.31

GC content: 37.68

Gene sequence:

>1173_bases
ATGAATCAAGGTCCACTTTCCGGAATCAAAGTAATCGACTTAAGTTTATTACTACCGGGTCCGTTATGTTCTATGTATTT
GGGAGATATGGGAGCTGAGATAATAAAGGTAGAAAATCCCAGAGCGATGGACGCAACTCGAGTAATGTTTAAAAAAGCGA
ACGGGGCCCCTTCTTTATATTTGATGCTCAATCGAAATAAAAAAGCGATCACTCTCAACTTAAAAAAGGAAAAATCTAGA
GAGATACTTTTTAAACTATTAGAAAATGCTGATATACTTCTGGAAGGATTTAGGCCGGATGGACTTGCCAAAATGGGATA
TGGATACGACGATTTAAAGGAACGTTTTCCTAAATTGATTTATTGTGGAATTTACGGATATGGAACGGAAGGAAAATATA
GAAATTTTGCGGGACACGATGTAAATTATCTCTCACTTTCCGGAGTACTTTCTCAGACTGGAAAAACACCTCAGATTCCA
GGATACCAACTTGCAGACATAGGAGGAGGGACGATGACGGCCCTTTCTTCAATTTTGGCGGCTTTGTATGCGAGGGAAAA
AACGGGAAAAGGACAAAAAATTTCCGTTTCTATGATGGATTCGTCATTGCCGTTTTTATCCTTGTATGGAGGGATTTACG
GAGCCACCGGAAAAAATCCAGAAGGAGGAAATGAACTACTTTCTGGTAAATTACCTAATTATAATGTTTATCAAACGAAG
GAGGGTCGTTGGGTCGCGTTAGGTGCTCTTGAAGATATGTTTTTTAAAACTTTTTTACGACAGACTGGGTTGGATAAACA
TTTGGAAGAATTACCTGCAGAAGAAAAAAACTTTTCTAAATGGAAAGAAATACTTACTACCTATTTTTCTACAAAAACAT
TCGAAGATTTGAATGTTCTTTTTGAAAACCAAGATTCCTGTCTAACTCCTGTAAAAACAATAGAAGAGGTCATTAAGGAC
CCGGTATTCCAGGAAAGTGGAATGGTTATTGAAAAAAAACATCCAGACTACGGAGATTATTTTCAGTTTGGGGCTCCTTT
TTCATTTTCCGAAACCCCTGTAACATATCGTTTGGACCCGCCGAGTCACGGGGAACATAATGAGTCTATCTATCGAACTT
TAGGGTATACAGTAGAAGAAATAGAAACGATGAAAAAAGAAAAAGTGATTTGA

Upstream 100 bases:

>100_bases
AGAATTTGTATGTAAATCGTAGTGAAGAAATAGTGAATATAAAAAAAGGTATCTCAAATAGATCTTTTCATCTGAATGGG
AGAAGAGAGGTCGTAAATCA

Downstream 100 bases:

>100_bases
ATTTCATTGGGAAACAATTGGAAGATACTAAATATTTTCTCAATTATAAACATTCTAAAAATTGTGAACAGAACGTTCGT
TCTTTGAAATTTTAGAAGGA

Product: alpha-methylacyl-CoA racemase

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MNQGPLSGIKVIDLSLLLPGPLCSMYLGDMGAEIIKVENPRAMDATRVMFKKANGAPSLYLMLNRNKKAITLNLKKEKSR
EILFKLLENADILLEGFRPDGLAKMGYGYDDLKERFPKLIYCGIYGYGTEGKYRNFAGHDVNYLSLSGVLSQTGKTPQIP
GYQLADIGGGTMTALSSILAALYAREKTGKGQKISVSMMDSSLPFLSLYGGIYGATGKNPEGGNELLSGKLPNYNVYQTK
EGRWVALGALEDMFFKTFLRQTGLDKHLEELPAEEKNFSKWKEILTTYFSTKTFEDLNVLFENQDSCLTPVKTIEEVIKD
PVFQESGMVIEKKHPDYGDYFQFGAPFSFSETPVTYRLDPPSHGEHNESIYRTLGYTVEEIETMKKEKVI

Sequences:

>Translated_390_residues
MNQGPLSGIKVIDLSLLLPGPLCSMYLGDMGAEIIKVENPRAMDATRVMFKKANGAPSLYLMLNRNKKAITLNLKKEKSR
EILFKLLENADILLEGFRPDGLAKMGYGYDDLKERFPKLIYCGIYGYGTEGKYRNFAGHDVNYLSLSGVLSQTGKTPQIP
GYQLADIGGGTMTALSSILAALYAREKTGKGQKISVSMMDSSLPFLSLYGGIYGATGKNPEGGNELLSGKLPNYNVYQTK
EGRWVALGALEDMFFKTFLRQTGLDKHLEELPAEEKNFSKWKEILTTYFSTKTFEDLNVLFENQDSCLTPVKTIEEVIKD
PVFQESGMVIEKKHPDYGDYFQFGAPFSFSETPVTYRLDPPSHGEHNESIYRTLGYTVEEIETMKKEKVI
>Mature_390_residues
MNQGPLSGIKVIDLSLLLPGPLCSMYLGDMGAEIIKVENPRAMDATRVMFKKANGAPSLYLMLNRNKKAITLNLKKEKSR
EILFKLLENADILLEGFRPDGLAKMGYGYDDLKERFPKLIYCGIYGYGTEGKYRNFAGHDVNYLSLSGVLSQTGKTPQIP
GYQLADIGGGTMTALSSILAALYAREKTGKGQKISVSMMDSSLPFLSLYGGIYGATGKNPEGGNELLSGKLPNYNVYQTK
EGRWVALGALEDMFFKTFLRQTGLDKHLEELPAEEKNFSKWKEILTTYFSTKTFEDLNVLFENQDSCLTPVKTIEEVIKD
PVFQESGMVIEKKHPDYGDYFQFGAPFSFSETPVTYRLDPPSHGEHNESIYRTLGYTVEEIETMKKEKVI

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI42794625, Length=392, Percent_Identity=32.6530612244898, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI266456254, Length=392, Percent_Identity=32.6530612244898, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI300863128, Length=380, Percent_Identity=31.5789473684211, Blast_Score=179, Evalue=5e-45,
Organism=Homo sapiens, GI300863124, Length=406, Percent_Identity=30.0492610837438, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI266458393, Length=264, Percent_Identity=35.9848484848485, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI266458397, Length=261, Percent_Identity=36.0153256704981, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI300863126, Length=379, Percent_Identity=28.4960422163588, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI13376042, Length=406, Percent_Identity=27.3399014778325, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI42822893, Length=169, Percent_Identity=33.7278106508876, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI266458395, Length=169, Percent_Identity=33.7278106508876, Blast_Score=106, Evalue=3e-23,
Organism=Escherichia coli, GI87082093, Length=339, Percent_Identity=29.7935103244838, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1788717, Length=425, Percent_Identity=28.2352941176471, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1786222, Length=402, Percent_Identity=24.6268656716418, Blast_Score=96, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI32564160, Length=318, Percent_Identity=33.6477987421384, Blast_Score=151, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI115535051, Length=316, Percent_Identity=31.3291139240506, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24648431, Length=399, Percent_Identity=33.5839598997494, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24585488, Length=321, Percent_Identity=32.7102803738318, Blast_Score=170, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 43626; Mature: 43626

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQGPLSGIKVIDLSLLLPGPLCSMYLGDMGAEIIKVENPRAMDATRVMFKKANGAPSLY
CCCCCCCCEEEEEEEEECCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCEEE
LMLNRNKKAITLNLKKEKSREILFKLLENADILLEGFRPDGLAKMGYGYDDLKERFPKLI
EEEECCCEEEEEEECHHHHHHHHHHHHCCCCEEEECCCCCCCHHCCCCHHHHHHHCCCEE
YCGIYGYGTEGKYRNFAGHDVNYLSLSGVLSQTGKTPQIPGYQLADIGGGTMTALSSILA
EEEEEEECCCCCCCCCCCCCCCEEEHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHH
ALYAREKTGKGQKISVSMMDSSLPFLSLYGGIYGATGKNPEGGNELLSGKLPNYNVYQTK
HHHHHHCCCCCCEEEEEEECCCCCHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCEEECC
EGRWVALGALEDMFFKTFLRQTGLDKHLEELPAEEKNFSKWKEILTTYFSTKTFEDLNVL
CCCEEEEHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHE
FENQDSCLTPVKTIEEVIKDPVFQESGMVIEKKHPDYGDYFQFGAPFSFSETPVTYRLDP
ECCCCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHCCCCCCCCCCCEEEEECC
PSHGEHNESIYRTLGYTVEEIETMKKEKVI
CCCCCCCHHHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MNQGPLSGIKVIDLSLLLPGPLCSMYLGDMGAEIIKVENPRAMDATRVMFKKANGAPSLY
CCCCCCCCEEEEEEEEECCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCEEE
LMLNRNKKAITLNLKKEKSREILFKLLENADILLEGFRPDGLAKMGYGYDDLKERFPKLI
EEEECCCEEEEEEECHHHHHHHHHHHHCCCCEEEECCCCCCCHHCCCCHHHHHHHCCCEE
YCGIYGYGTEGKYRNFAGHDVNYLSLSGVLSQTGKTPQIPGYQLADIGGGTMTALSSILA
EEEEEEECCCCCCCCCCCCCCCEEEHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHH
ALYAREKTGKGQKISVSMMDSSLPFLSLYGGIYGATGKNPEGGNELLSGKLPNYNVYQTK
HHHHHHCCCCCCEEEEEEECCCCCHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCEEECC
EGRWVALGALEDMFFKTFLRQTGLDKHLEELPAEEKNFSKWKEILTTYFSTKTFEDLNVL
CCCEEEEHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHE
FENQDSCLTPVKTIEEVIKDPVFQESGMVIEKKHPDYGDYFQFGAPFSFSETPVTYRLDP
ECCCCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHCCCCCCCCCCCEEEEECC
PSHGEHNESIYRTLGYTVEEIETMKKEKVI
CCCCCCCHHHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]