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The map label for this gene is dapB

Identifier: 45656734

GI number: 45656734

Start: 1022521

End: 1023333

Strand: Direct

Name: dapB

Synonym: LIC10843

Alternate gene names: 45656734

Gene position: 1022521-1023333 (Clockwise)

Preceding gene: 45656733

Following gene: 45656735

Centisome position: 23.91

GC content: 40.34

Gene sequence:

>813_bases
ATGAGTCAACCTTCAAAAACTCAAATCGCTTTGATCGGAGCGTCCGGAAGAATGGGGCGCGCCATTGTCTCCGTACTTTC
TACTTCTGTTAAATCCACGTTATCTTCATCGGTAGTTAGTCAAAGTTCTGTATTTTTAGGAATGGATTCTGGACTACATT
CTGGGATCAAACAAAACGGAGTGAATTTTTCCTCCGATTTAGAAGCCGCGGTACGGAGCGCGGATTGTGTAATTGATTTC
AGCACACATCAAAATTTAGATTTTACACTTAAGGCTTGTATTCAATATCAAAAACCGGTTGTAATTGGAATTACAGGACT
CACAGAGCTTCAAAAAGATGCGTTGCAAGTGGCTTCTAAAGAAATCGGAATCGTGTATTCACCTAATATGTCTATTGGAG
TAAACTTATTGTTCAAGTTAACCGAAATTGCGGCCAAGGTAATGGGGGAAATTTCGGACATAGAAATCCAGGACATTCAT
CATCGTCATAAAAAGGATGCACCTTCGGGAACCGCTGAAAAATTAAAGAGCATACTTTTAGAAACGTTAGGCAGAACGTC
TAAAAACGTAGTCCACGGAAGACACGGGATTTTAAAAGAAAGAGATTCCAAAGAAATAGGAATCCACACGTTTCGAGCGG
GAGAAGTGATTGGAGATCATACCGTATATTTTTTTACTCCTGAAGAAAGGATAGAAATAACACATAAGGCTCAGGATCGA
AAAACCTTTGCAGTAGGAAGTGTACACGCGGCAGAATTTTTAGTAGGCCGCAAGCCGGGACTTTACGATATGTTTGCGGT
TTTAGGATTATAG

Upstream 100 bases:

>100_bases
GGAAATACGACTTCCGTTGACTCCACTTTCTCAAAACGAGACAAGTTCTAAATTTAAAAAGGTGCTCGAAGGTCTGAAAG
AAAAAGGATACGAATAGAGA

Downstream 100 bases:

>100_bases
AGGAAGTTAGGATTGTTTTTTTTCAAGAACATATCCCTGTTCCCACTCGGTAAAAATCCGTTCATTATCATCATTGATAT
ACTCATCGTAAGTTTTTTCA

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MSQPSKTQIALIGASGRMGRAIVSVLSTSVKSTLSSSVVSQSSVFLGMDSGLHSGIKQNGVNFSSDLEAAVRSADCVIDF
STHQNLDFTLKACIQYQKPVVIGITGLTELQKDALQVASKEIGIVYSPNMSIGVNLLFKLTEIAAKVMGEISDIEIQDIH
HRHKKDAPSGTAEKLKSILLETLGRTSKNVVHGRHGILKERDSKEIGIHTFRAGEVIGDHTVYFFTPEERIEITHKAQDR
KTFAVGSVHAAEFLVGRKPGLYDMFAVLGL

Sequences:

>Translated_270_residues
MSQPSKTQIALIGASGRMGRAIVSVLSTSVKSTLSSSVVSQSSVFLGMDSGLHSGIKQNGVNFSSDLEAAVRSADCVIDF
STHQNLDFTLKACIQYQKPVVIGITGLTELQKDALQVASKEIGIVYSPNMSIGVNLLFKLTEIAAKVMGEISDIEIQDIH
HRHKKDAPSGTAEKLKSILLETLGRTSKNVVHGRHGILKERDSKEIGIHTFRAGEVIGDHTVYFFTPEERIEITHKAQDR
KTFAVGSVHAAEFLVGRKPGLYDMFAVLGL
>Mature_269_residues
SQPSKTQIALIGASGRMGRAIVSVLSTSVKSTLSSSVVSQSSVFLGMDSGLHSGIKQNGVNFSSDLEAAVRSADCVIDFS
THQNLDFTLKACIQYQKPVVIGITGLTELQKDALQVASKEIGIVYSPNMSIGVNLLFKLTEIAAKVMGEISDIEIQDIHH
RHKKDAPSGTAEKLKSILLETLGRTSKNVVHGRHGILKERDSKEIGIHTFRAGEVIGDHTVYFFTPEERIEITHKAQDRK
TFAVGSVHAAEFLVGRKPGLYDMFAVLGL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=267, Percent_Identity=41.5730337078652, Blast_Score=185, Evalue=3e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_LEPIC (Q72U21)

Other databases:

- EMBL:   AE016823
- RefSeq:   YP_000820.1
- ProteinModelPortal:   Q72U21
- SMR:   Q72U21
- GeneID:   2772358
- GenomeReviews:   AE016823_GR
- KEGG:   lic:LIC10843
- HOGENOM:   HBG594002
- OMA:   GALKACE
- ProtClustDB:   PRK00048
- BioCyc:   LINT267671:LIC_10843-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 29259; Mature: 29128

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPSKTQIALIGASGRMGRAIVSVLSTSVKSTLSSSVVSQSSVFLGMDSGLHSGIKQNG
CCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHCC
VNFSSDLEAAVRSADCVIDFSTHQNLDFTLKACIQYQKPVVIGITGLTELQKDALQVASK
CCCCHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHH
EIGIVYSPNMSIGVNLLFKLTEIAAKVMGEISDIEIQDIHHRHKKDAPSGTAEKLKSILL
HCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHH
ETLGRTSKNVVHGRHGILKERDSKEIGIHTFRAGEVIGDHTVYFFTPEERIEITHKAQDR
HHHCCCCHHHHCCCCCCCCCCCCCCCCEEEEECCCEECCCEEEEECCHHHEEEEECCCCC
KTFAVGSVHAAEFLVGRKPGLYDMFAVLGL
CEEEECCHHHHHHHHCCCCCHHHHHHHHCC
>Mature Secondary Structure 
SQPSKTQIALIGASGRMGRAIVSVLSTSVKSTLSSSVVSQSSVFLGMDSGLHSGIKQNG
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHCC
VNFSSDLEAAVRSADCVIDFSTHQNLDFTLKACIQYQKPVVIGITGLTELQKDALQVASK
CCCCHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHH
EIGIVYSPNMSIGVNLLFKLTEIAAKVMGEISDIEIQDIHHRHKKDAPSGTAEKLKSILL
HCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHH
ETLGRTSKNVVHGRHGILKERDSKEIGIHTFRAGEVIGDHTVYFFTPEERIEITHKAQDR
HHHCCCCHHHHCCCCCCCCCCCCCCCCEEEEECCCEECCCEEEEECCHHHEEEEECCCCC
KTFAVGSVHAAEFLVGRKPGLYDMFAVLGL
CEEEECCHHHHHHHHCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA