Click here to switch to the map view.

The map label for this gene is crp [C]

Identifier: 45656684

GI number: 45656684

Start: 961450

End: 962082

Strand: Direct

Name: crp [C]

Synonym: LIC10791

Alternate gene names: 45656684

Gene position: 961450-962082 (Clockwise)

Preceding gene: 45656682

Following gene: 45656685

Centisome position: 22.48

GC content: 37.76

Gene sequence:

>633_bases
ATGAAAGTAACCGAGTCCATGATTGAGAAATTAGGGGTCGAATTCAAAGAATCCGATATTATCTTTGAGGAAAATCAGGA
AGCGGAGGAAATGTATCTGATCGTCAGCGGGAAAGTCGGAATTCACAAAAAAGTAAAAGAAGCCTATAAACTCCTCGTAG
AATTAAAAGAGGGGGATATGTTCGGCGAAATGGCACTGATCGATAGAACTCCTCGAAGCGCAAGGGCGGTTGCAAAAACT
GACGTTTCACTCATCGCAATCAATGAAAGCGCATTTTTCAATTTAATACGAACCAATCCCGGTTTTTCCATGAAAATTGT
TAAGATCCTTACTTCCAGATTGAGAGAAACTAACAAAACGATTGCTACTCTTTTAAAAGCGGATAAAAAGAATTTAGTAA
CTTCGGCTTTGATCAATTTTTCCCAAACATACGGAACACAAGATGGTAGTATCTGTAAAATTCCTTTGAATCATTTTATT
CGATGGGCGATCCTTAGAGTTGGATTGGAGCACAAGGACCTGGTCAGTGCAATTAATCTATTAGTAAAAGATAAAATGGT
AGAACAAAAAAAGGAAGACCCTGCAACCTTAATCCTTCGAGATTCTCTTTTTAAATATACGGTGGATGTTTGA

Upstream 100 bases:

>100_bases
CGGATTTTAGTTGATCTAAGTTCAGAAGCTTTCGATGCTGGTTCCGTTCTCCAAATAATTGAATTGATTGTGATATTATA
ATTAAGGTCCGTTAAGAATT

Downstream 100 bases:

>100_bases
ACCTTAAGTCGACTTTACCCAAAACTCGAAAAAGACTTTTTTATCTAGATAACCTTCGTTCCTTTGCTCTTTTAACTGGT
CTAGTGTTTCATGTGGCGAT

Product: cyclic nucleotide binding protein

Products: NA

Alternate protein names: Crp/Fnr Family Transcriptional Regulator; Transcriptional Regulator; Transcriptional Regulatory Protein; Crp Family Transcriptional Regulator; Crp/FNR Family Transcriptional Regulator; Histidine Kinase; CRP Family Transcriptional Regulator; Catabolite Gene Activator; Regulatory Protein; Transcription Regulator; CAMP-Dependent Protein Kinase; Transcriptional Regulator Crp/Fnr Family Protein

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MKVTESMIEKLGVEFKESDIIFEENQEAEEMYLIVSGKVGIHKKVKEAYKLLVELKEGDMFGEMALIDRTPRSARAVAKT
DVSLIAINESAFFNLIRTNPGFSMKIVKILTSRLRETNKTIATLLKADKKNLVTSALINFSQTYGTQDGSICKIPLNHFI
RWAILRVGLEHKDLVSAINLLVKDKMVEQKKEDPATLILRDSLFKYTVDV

Sequences:

>Translated_210_residues
MKVTESMIEKLGVEFKESDIIFEENQEAEEMYLIVSGKVGIHKKVKEAYKLLVELKEGDMFGEMALIDRTPRSARAVAKT
DVSLIAINESAFFNLIRTNPGFSMKIVKILTSRLRETNKTIATLLKADKKNLVTSALINFSQTYGTQDGSICKIPLNHFI
RWAILRVGLEHKDLVSAINLLVKDKMVEQKKEDPATLILRDSLFKYTVDV
>Mature_210_residues
MKVTESMIEKLGVEFKESDIIFEENQEAEEMYLIVSGKVGIHKKVKEAYKLLVELKEGDMFGEMALIDRTPRSARAVAKT
DVSLIAINESAFFNLIRTNPGFSMKIVKILTSRLRETNKTIATLLKADKKNLVTSALINFSQTYGTQDGSICKIPLNHFI
RWAILRVGLEHKDLVSAINLLVKDKMVEQKKEDPATLILRDSLFKYTVDV

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 23780; Mature: 23780

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS00889 CNMP_BINDING_2 ; PS50042 CNMP_BINDING_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVTESMIEKLGVEFKESDIIFEENQEAEEMYLIVSGKVGIHKKVKEAYKLLVELKEGDM
CCCHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCC
FGEMALIDRTPRSARAVAKTDVSLIAINESAFFNLIRTNPGFSMKIVKILTSRLRETNKT
CCCCCEEECCCCHHHHHHHCCEEEEEECCHHHEEEEECCCCCCHHHHHHHHHHHHHHHHH
IATLLKADKKNLVTSALINFSQTYGTQDGSICKIPLNHFIRWAILRVGLEHKDLVSAINL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHCCCHHHHHHHHHH
LVKDKMVEQKKEDPATLILRDSLFKYTVDV
HHHHHHHHHHCCCCCEEEEEHHHHEEEECC
>Mature Secondary Structure
MKVTESMIEKLGVEFKESDIIFEENQEAEEMYLIVSGKVGIHKKVKEAYKLLVELKEGDM
CCCHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCC
FGEMALIDRTPRSARAVAKTDVSLIAINESAFFNLIRTNPGFSMKIVKILTSRLRETNKT
CCCCCEEECCCCHHHHHHHCCEEEEEECCHHHEEEEECCCCCCHHHHHHHHHHHHHHHHH
IATLLKADKKNLVTSALINFSQTYGTQDGSICKIPLNHFIRWAILRVGLEHKDLVSAINL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHCCCHHHHHHHHHH
LVKDKMVEQKKEDPATLILRDSLFKYTVDV
HHHHHHHHHHCCCCCEEEEEHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA