| Definition | Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_005823 |
| Length | 4,277,185 |
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The map label for this gene is greA
Identifier: 45656682
GI number: 45656682
Start: 956203
End: 958983
Strand: Direct
Name: greA
Synonym: LIC10789
Alternate gene names: 45656682
Gene position: 956203-958983 (Clockwise)
Preceding gene: 45656681
Following gene: 45656684
Centisome position: 22.36
GC content: 36.57
Gene sequence:
>2781_bases ATGTCTAACGAAATATCAGCAACTACGGAATCCAGACCGGCTAACGATCTGGATAAGCTGACATCTCTTTTCAACGAAGA AATTTACGTTCGCACTGATGCGAATTCCATTCCTGCATCCAAGTTCAAGATTTTTGATGATCTCATCGAATTTTATAAGT CAGCCGGAAAAATAGACGAAGCAAAACGAAAAATCGAAGAATATCTTTCTGAACACGAAGATAGTATCTCCGCAAGATAT TTACTTGGGATTCTTTCTTTGGAAAGAGGGGAGATTAGCGATTCTGGTCTATTAAAGAATCTATTAGAATCTTTTAAAGT AGCCAGTAAATGGGCTATTATAGAACACATTACGGATCAAATCCTGAAATATGGAGATCAAAGACTCGCGCTTAAATACA AAGCAGAAGCTCTGGAAAAATTAAAAAAGAATAAAGAACTTAAAATCGTATTAGAAAAGCTTGCAAAACACGATCGTAAA AATCCAGAAATTTTAAAAAAATATGCCCTGTCTATATTAGAAGAAAATAAAGAAAAGGCGATTACGTATCTCAAACAAGC GATCGAAACATTTGCTAAAACAAAGGATTACGTTCAGTTAGAAGAGATTTGGTCGATCATCGTAAATAATAATCATGAGG ACCTTCAATTTTTCGAAAGAATTGAAAGAATCATGTTAGGTCATCGCGAAAGAACCAGACTCGTGGGTTATCTTTATCCG ATTGTGGAACCTTATAAACAGTTGGAAGACTGGGACAAGGTGATTTATCTTTTAAAAAAGATTTTAGAACACGAGGCTTC TTCTAACAAAGCCAGAAATGAACTCATCAGAGCTTATAAAGCAAAGTATGTAAATCATTCCCTTTTGGAAGATTTTCTAA AGATGTCTGAGATCGGCAATAATAGAAAGCCGATCAAGGTATGTATCGCAAATTTCGAAAGGAACATCGTATTCGATACT AACAATTACGTTCTACATAGAAACTGGGGTGTGGGGAAAATTACTTCAATTTCGCCTAACGGAGATTCTATCTTTGTAGA TTTTAAAGATAAGAAGGACCATAAACTTTCAATTCAGATGGCGATTACCAGTTTAAAGCCTCTGAAAAGAGATCACATCT GGGTAAAATACTATGAAAATAAAGATGAGATTACAGAATTATTTAAAAATAATATTCCTGATTTTTTTAAAGAACTCTTA ACTTCTTTTAACAACAGAATGTTGACTGCTGATATTAAATCAGAAGTTTCCGGAAAATTTCTTCCGGTTGCAGAATGGTC CAAGTGGTGGAACAAAGCTAAGAATATCATTAAAAAAGAACCCAATATTGGATTTGATCCAAAGAAAAAAGATGAATTGG TATATCGTGAAAAAGCCATTTCTTTGTCGGAAGAATTGTCGGAGAAGTTTGCTCACCAGACAGACGCAAATAAAAAACTA GATATTGCAATGGAAGCTTTGGATAACCGAGAAGATGCGGAAGGAGCCATTGAAGCTTTCAATCACTTTTATTATGAAGA AGAGGAAGCGGCAGATCCGGTTCGTAAGATTGTAGCGTTTTTATATTTGCAAACTGCGTCGGAAGAACTTGGAGACGAGG AAATTCCAAGACATCTAAACGAATCTAAAATTGCAGAATTGATTAAGTCTTTGCCAGTTAGTTCTTTAATTGAGGTTTCT ACTAAAATTGGAAACGCGGAAATCAAAAAGGGTTACGTAAACTTAGTTCGCAAACACGCTCACAATCCGGAAGAGGTTTT GACCGGAATTCTTTTCGAAGTTCCAATTAAGGTAAACAAATACGTATTCTCCATTTTGGAAGAAGAAGGTAAGTTTGATC TTCTTAATTCATTTATTAAGTCTGCTGGCACGAGAGCAAAAGAAACTCCTGAAGTTTTTATCTGGGTTGCTAAATCCATT CTTACCAAAGTTTGGGAAGGAGAATGGCTTTTATCTTCTAAACAAGAGGAACGTCTTGAATTGATCCTCAAAGTTTTCCG TATGTTTAAACCTCTTACTAAGATAGAGGATAAGGGAACTAAACTCAAGAATGCTTGTAAAGACATCTTACACGGTAACG ACGATGAGATTTTACGCGAAGCAATTCATGCTGGAAATTCTGAATACATCCGTAAGTTATACGCCCTTTATAAAGAGGTT CCGTATTTTACTGATCTTGAAAAAGAACGTCTGTATTCTTTGATTGTAGAGTTAAAACCTGACGTTGCTTGGGAAGAAGA TGAAGACGAGGATGAAGAAGATGACGACATTCTCACTCGGATTCCTGAAGGTGCGATTTTGGTTACAAGACGCGCACTCA ATCGGAAAAAAGAAGAATTTGAACACCTACTTAATGTAGAGATGCCGGAAAATTCCAAAGATATTGGAGAAGCTCAGGAA AGAGGGGACTTGCGGGAAAACGCTGAATATAAAGCCGCTATGGAAAAACAAGTTCAATTGCAGGCGGCGATTAAAAGGTT GGAAGCGGAAATCAAAAGTGCGATTATTTTGGATCTTACCAACGTTAAGACGGACAAGATCAACATCGGAGTTACGGCAA AACTTAAAAATGAATCTACAGGAGAAGTTGTAGCGTATTCTATTTTGGGTGCTTGGGATGCGGATACGGAAAAACATATC ATCAGCTATCAGTCTCCGCTGGCTAAATCTTTGCTTGGTAAAAAAACGGGGGATTCCGCCGTTTTAAATCTTACCGGAGC GGAAACCCGTTATACGGTTTTAGATATTAGCAGATTTTCTTTACAGAGCCAAGAAAATTAG
Upstream 100 bases:
>100_bases CTCGCTTATAATTGATAAATACAGGGCTGTCAGAGAGGAATTTTACCCCAAACGTCCCAATTTTCATCATCAAGCCGAGA TTCAATCGGTGGAGTATCCT
Downstream 100 bases:
>100_bases AAAATATATTCAGAAAACAGAATGTATTAAAAAATCCCGGATCGTTTTTCGGTTCGGGATTTTTTTATCTATTGAAACAA AAATGAGAATCAGTGCAACG
Product: transcript cleavage factor/unknown domain fusion protein
Products: NA
Alternate protein names: Transcript cleavage factor greA [H]
Number of amino acids: Translated: 926; Mature: 925
Protein sequence:
>926_residues MSNEISATTESRPANDLDKLTSLFNEEIYVRTDANSIPASKFKIFDDLIEFYKSAGKIDEAKRKIEEYLSEHEDSISARY LLGILSLERGEISDSGLLKNLLESFKVASKWAIIEHITDQILKYGDQRLALKYKAEALEKLKKNKELKIVLEKLAKHDRK NPEILKKYALSILEENKEKAITYLKQAIETFAKTKDYVQLEEIWSIIVNNNHEDLQFFERIERIMLGHRERTRLVGYLYP IVEPYKQLEDWDKVIYLLKKILEHEASSNKARNELIRAYKAKYVNHSLLEDFLKMSEIGNNRKPIKVCIANFERNIVFDT NNYVLHRNWGVGKITSISPNGDSIFVDFKDKKDHKLSIQMAITSLKPLKRDHIWVKYYENKDEITELFKNNIPDFFKELL TSFNNRMLTADIKSEVSGKFLPVAEWSKWWNKAKNIIKKEPNIGFDPKKKDELVYREKAISLSEELSEKFAHQTDANKKL DIAMEALDNREDAEGAIEAFNHFYYEEEEAADPVRKIVAFLYLQTASEELGDEEIPRHLNESKIAELIKSLPVSSLIEVS TKIGNAEIKKGYVNLVRKHAHNPEEVLTGILFEVPIKVNKYVFSILEEEGKFDLLNSFIKSAGTRAKETPEVFIWVAKSI LTKVWEGEWLLSSKQEERLELILKVFRMFKPLTKIEDKGTKLKNACKDILHGNDDEILREAIHAGNSEYIRKLYALYKEV PYFTDLEKERLYSLIVELKPDVAWEEDEDEDEEDDDILTRIPEGAILVTRRALNRKKEEFEHLLNVEMPENSKDIGEAQE RGDLRENAEYKAAMEKQVQLQAAIKRLEAEIKSAIILDLTNVKTDKINIGVTAKLKNESTGEVVAYSILGAWDADTEKHI ISYQSPLAKSLLGKKTGDSAVLNLTGAETRYTVLDISRFSLQSQEN
Sequences:
>Translated_926_residues MSNEISATTESRPANDLDKLTSLFNEEIYVRTDANSIPASKFKIFDDLIEFYKSAGKIDEAKRKIEEYLSEHEDSISARY LLGILSLERGEISDSGLLKNLLESFKVASKWAIIEHITDQILKYGDQRLALKYKAEALEKLKKNKELKIVLEKLAKHDRK NPEILKKYALSILEENKEKAITYLKQAIETFAKTKDYVQLEEIWSIIVNNNHEDLQFFERIERIMLGHRERTRLVGYLYP IVEPYKQLEDWDKVIYLLKKILEHEASSNKARNELIRAYKAKYVNHSLLEDFLKMSEIGNNRKPIKVCIANFERNIVFDT NNYVLHRNWGVGKITSISPNGDSIFVDFKDKKDHKLSIQMAITSLKPLKRDHIWVKYYENKDEITELFKNNIPDFFKELL TSFNNRMLTADIKSEVSGKFLPVAEWSKWWNKAKNIIKKEPNIGFDPKKKDELVYREKAISLSEELSEKFAHQTDANKKL DIAMEALDNREDAEGAIEAFNHFYYEEEEAADPVRKIVAFLYLQTASEELGDEEIPRHLNESKIAELIKSLPVSSLIEVS TKIGNAEIKKGYVNLVRKHAHNPEEVLTGILFEVPIKVNKYVFSILEEEGKFDLLNSFIKSAGTRAKETPEVFIWVAKSI LTKVWEGEWLLSSKQEERLELILKVFRMFKPLTKIEDKGTKLKNACKDILHGNDDEILREAIHAGNSEYIRKLYALYKEV PYFTDLEKERLYSLIVELKPDVAWEEDEDEDEEDDDILTRIPEGAILVTRRALNRKKEEFEHLLNVEMPENSKDIGEAQE RGDLRENAEYKAAMEKQVQLQAAIKRLEAEIKSAIILDLTNVKTDKINIGVTAKLKNESTGEVVAYSILGAWDADTEKHI ISYQSPLAKSLLGKKTGDSAVLNLTGAETRYTVLDISRFSLQSQEN >Mature_925_residues SNEISATTESRPANDLDKLTSLFNEEIYVRTDANSIPASKFKIFDDLIEFYKSAGKIDEAKRKIEEYLSEHEDSISARYL LGILSLERGEISDSGLLKNLLESFKVASKWAIIEHITDQILKYGDQRLALKYKAEALEKLKKNKELKIVLEKLAKHDRKN PEILKKYALSILEENKEKAITYLKQAIETFAKTKDYVQLEEIWSIIVNNNHEDLQFFERIERIMLGHRERTRLVGYLYPI VEPYKQLEDWDKVIYLLKKILEHEASSNKARNELIRAYKAKYVNHSLLEDFLKMSEIGNNRKPIKVCIANFERNIVFDTN NYVLHRNWGVGKITSISPNGDSIFVDFKDKKDHKLSIQMAITSLKPLKRDHIWVKYYENKDEITELFKNNIPDFFKELLT SFNNRMLTADIKSEVSGKFLPVAEWSKWWNKAKNIIKKEPNIGFDPKKKDELVYREKAISLSEELSEKFAHQTDANKKLD IAMEALDNREDAEGAIEAFNHFYYEEEEAADPVRKIVAFLYLQTASEELGDEEIPRHLNESKIAELIKSLPVSSLIEVST KIGNAEIKKGYVNLVRKHAHNPEEVLTGILFEVPIKVNKYVFSILEEEGKFDLLNSFIKSAGTRAKETPEVFIWVAKSIL TKVWEGEWLLSSKQEERLELILKVFRMFKPLTKIEDKGTKLKNACKDILHGNDDEILREAIHAGNSEYIRKLYALYKEVP YFTDLEKERLYSLIVELKPDVAWEEDEDEDEEDDDILTRIPEGAILVTRRALNRKKEEFEHLLNVEMPENSKDIGEAQER GDLRENAEYKAAMEKQVQLQAAIKRLEAEIKSAIILDLTNVKTDKINIGVTAKLKNESTGEVVAYSILGAWDADTEKHII SYQSPLAKSLLGKKTGDSAVLNLTGAETRYTVLDISRFSLQSQEN
Specific function: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary
COG id: COG1747
COG function: function code S; Uncharacterized N-terminal domain of the transcription elongation factor GreA
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 GRAD2 (greA associated 2) domain [H]
Homologues:
Organism=Escherichia coli, GI87082225, Length=153, Percent_Identity=35.9477124183007, Blast_Score=96, Evalue=9e-21, Organism=Escherichia coli, GI87082261, Length=147, Percent_Identity=29.2517006802721, Blast_Score=65, Evalue=1e-11,
Paralogues:
None
Copy number: 259 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR018151 - InterPro: IPR011990 - InterPro: IPR006359 - InterPro: IPR001437 - InterPro: IPR022691 [H]
Pfam domain/function: PF01272 GreA_GreB; PF03449 GreA_GreB_N [H]
EC number: NA
Molecular weight: Translated: 106949; Mature: 106818
Theoretical pI: Translated: 5.62; Mature: 5.62
Prosite motif: PS00830 GREAB_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 1.0 %Met (Translated Protein) 1.2 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 0.9 %Met (Mature Protein) 1.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSNEISATTESRPANDLDKLTSLFNEEIYVRTDANSIPASKFKIFDDLIEFYKSAGKIDE CCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHH AKRKIEEYLSEHEDSISARYLLGILSLERGEISDSGLLKNLLESFKVASKWAIIEHITDQ HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH ILKYGDQRLALKYKAEALEKLKKNKELKIVLEKLAKHDRKNPEILKKYALSILEENKEKA HHHCCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHH ITYLKQAIETFAKTKDYVQLEEIWSIIVNNNHEDLQFFERIERIMLGHRERTRLVGYLYP HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH IVEPYKQLEDWDKVIYLLKKILEHEASSNKARNELIRAYKAKYVNHSLLEDFLKMSEIGN HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC NRKPIKVCIANFERNIVFDTNNYVLHRNWGVGKITSISPNGDSIFVDFKDKKDHKLSIQM CCCCHHHHEECCCCCEEEECCCEEEEECCCCCEEEEECCCCCEEEEEECCCCCCEEEEEE AITSLKPLKRDHIWVKYYENKDEITELFKNNIPDFFKELLTSFNNRMLTADIKSEVSGKF HHHHHCCCCCCCEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEHHHHCCCCC LPVAEWSKWWNKAKNIIKKEPNIGFDPKKKDELVYREKAISLSEELSEKFAHQTDANKKL CCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH DIAMEALDNREDAEGAIEAFNHFYYEEEEAADPVRKIVAFLYLQTASEELGDEEIPRHLN HHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC ESKIAELIKSLPVSSLIEVSTKIGNAEIKKGYVNLVRKHAHNPEEVLTGILFEVPIKVNK HHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHH YVFSILEEEGKFDLLNSFIKSAGTRAKETPEVFIWVAKSILTKVWEGEWLLSSKQEERLE HHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCHHHHHH LILKVFRMFKPLTKIEDKGTKLKNACKDILHGNDDEILREAIHAGNSEYIRKLYALYKEV HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHC PYFTDLEKERLYSLIVELKPDVAWEEDEDEDEEDDDILTRIPEGAILVTRRALNRKKEEF CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCEEHHHHHHHHHHHHH EHLLNVEMPENSKDIGEAQERGDLRENAEYKAAMEKQVQLQAAIKRLEAEIKSAIILDLT HHHHCCCCCCCCCHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEC NVKTDKINIGVTAKLKNESTGEVVAYSILGAWDADTEKHIISYQSPLAKSLLGKKTGDSA CCCCCEEEEEEEEEECCCCCCCEEEEHHHCCCCCCCHHHHHHHCCHHHHHHHCCCCCCCE VLNLTGAETRYTVLDISRFSLQSQEN EEEECCCCCEEEEEEHHHHHCCCCCC >Mature Secondary Structure SNEISATTESRPANDLDKLTSLFNEEIYVRTDANSIPASKFKIFDDLIEFYKSAGKIDE CCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHH AKRKIEEYLSEHEDSISARYLLGILSLERGEISDSGLLKNLLESFKVASKWAIIEHITDQ HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH ILKYGDQRLALKYKAEALEKLKKNKELKIVLEKLAKHDRKNPEILKKYALSILEENKEKA HHHCCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHH ITYLKQAIETFAKTKDYVQLEEIWSIIVNNNHEDLQFFERIERIMLGHRERTRLVGYLYP HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH IVEPYKQLEDWDKVIYLLKKILEHEASSNKARNELIRAYKAKYVNHSLLEDFLKMSEIGN HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC NRKPIKVCIANFERNIVFDTNNYVLHRNWGVGKITSISPNGDSIFVDFKDKKDHKLSIQM CCCCHHHHEECCCCCEEEECCCEEEEECCCCCEEEEECCCCCEEEEEECCCCCCEEEEEE AITSLKPLKRDHIWVKYYENKDEITELFKNNIPDFFKELLTSFNNRMLTADIKSEVSGKF HHHHHCCCCCCCEEEEEECCHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEHHHHCCCCC LPVAEWSKWWNKAKNIIKKEPNIGFDPKKKDELVYREKAISLSEELSEKFAHQTDANKKL CCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH DIAMEALDNREDAEGAIEAFNHFYYEEEEAADPVRKIVAFLYLQTASEELGDEEIPRHLN HHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCC ESKIAELIKSLPVSSLIEVSTKIGNAEIKKGYVNLVRKHAHNPEEVLTGILFEVPIKVNK HHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHH YVFSILEEEGKFDLLNSFIKSAGTRAKETPEVFIWVAKSILTKVWEGEWLLSSKQEERLE HHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCHHHHHH LILKVFRMFKPLTKIEDKGTKLKNACKDILHGNDDEILREAIHAGNSEYIRKLYALYKEV HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHC PYFTDLEKERLYSLIVELKPDVAWEEDEDEDEEDDDILTRIPEGAILVTRRALNRKKEEF CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCEEHHHHHHHHHHHHH EHLLNVEMPENSKDIGEAQERGDLRENAEYKAAMEKQVQLQAAIKRLEAEIKSAIILDLT HHHHCCCCCCCCCHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEC NVKTDKINIGVTAKLKNESTGEVVAYSILGAWDADTEKHIISYQSPLAKSLLGKKTGDSA CCCCCEEEEEEEEEECCCCCCCEEEEHHHCCCCCCCHHHHHHHCCHHHHHHHCCCCCCCE VLNLTGAETRYTVLDISRFSLQSQEN EEEECCCCCEEEEEEHHHHHCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9403685 [H]