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The map label for this gene is hrcA

Identifier: 45656424

GI number: 45656424

Start: 634486

End: 635514

Strand: Reverse

Name: hrcA

Synonym: LIC10526

Alternate gene names: 45656424

Gene position: 635514-634486 (Counterclockwise)

Preceding gene: 45656425

Following gene: 45656423

Centisome position: 14.86

GC content: 37.32

Gene sequence:

>1029_bases
ATGGATTTGACAGAGCGCCATAAAAGAATTCTAAAAGCACTTGTAGACGAGTTTATCCAAGAGAATCGACCCGTAGGTTC
TAAAACACTTTTTGATAAACACGATATAGGGCTATCACCCGCTTCAATTCGAACCGTATTGAAGGACTTAGAAGACTTCG
GCTATCTTGCGTCCAAACATACTTCGGGTGGAAGAATTCCAACAGAGAGGGGTTATCGTTTTTACGTAGATTCTCTTGTA
ATTTTATACGAGCTGACTCTAAAAGAAAAACAAAGAATTCAACAAGAATATCTGAAGATGCAATTTAAACTCGATCAGAT
ATTAAAGGCAACTGCATCGGTACTTTCTTCTTTATCAAACGCAGCGGGAATTGTAATCGGACCTGCAAAAAATTTAGATA
CTCTGAAACATATAGAACTCATCCACGTTCGTGGAGACGAAATTCTAATGATACTTGTCATGAGATCGGGAACCGTATTA
CACAGAAATATTTTCGTGGATCAAAATTATTCTCAGGAAGCGCTTTATCAGGTTTCTAAATATCTAAATGATAATCTAAA
AGGTTACGATATATACGAAATTCAGAATGTAATCATTCCAAAATTGATGATCCGAAAAGACGGACCGGAAGATTTTATTA
GGATCGCAGATCTGATTTCTTCCGCAATGACACCAGATAATTCCGAAGTAACTTTATATATAGACGGATTTAAAAATCTT
TACGCGAATTTCAGAGACGAAGAACAACAACTTTCTCAAGTTCTTTCTCTTCTGGACGATCAAGGATTTTTAAAAGCATT
TTTTTCCGAATACATCGACCAAGACGGAGTATTTACGATCATCGGAAAAGACGGTGATAGAAGTATGTCCGGAGTTTCCA
TTATCACTTCCAACTATAAAATGGGAGAAAAAAAGATCGGAGCCTTGGGAATTATAGGACCTCAGAGAATGGATTACAAT
AGAGCCTTACCGCTCGTCGACTTCACGTCGAAACTTGTCTCCGAAATGGTGACTCGCATTAGTAAATAA

Upstream 100 bases:

>100_bases
ACCAAAACGGAATCAGATTACTTTCTTCCTTGACATTTTTTAAAGGAATTCAGAAACTAAATGTATAAATTAGCACTCTA
ACATTAAGAGTGCCAGAGCT

Downstream 100 bases:

>100_bases
GGGAGAATTCAATATGGCCGAAACGTCAAACAATAAAACTTCGGAAGAAGCAAAGGCCAATGAGAAAAAATCTCAATCAG
AAACATTAGAGGAAAGTAAA

Product: heat-inducible transcriptional repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MDLTERHKRILKALVDEFIQENRPVGSKTLFDKHDIGLSPASIRTVLKDLEDFGYLASKHTSGGRIPTERGYRFYVDSLV
ILYELTLKEKQRIQQEYLKMQFKLDQILKATASVLSSLSNAAGIVIGPAKNLDTLKHIELIHVRGDEILMILVMRSGTVL
HRNIFVDQNYSQEALYQVSKYLNDNLKGYDIYEIQNVIIPKLMIRKDGPEDFIRIADLISSAMTPDNSEVTLYIDGFKNL
YANFRDEEQQLSQVLSLLDDQGFLKAFFSEYIDQDGVFTIIGKDGDRSMSGVSIITSNYKMGEKKIGALGIIGPQRMDYN
RALPLVDFTSKLVSEMVTRISK

Sequences:

>Translated_342_residues
MDLTERHKRILKALVDEFIQENRPVGSKTLFDKHDIGLSPASIRTVLKDLEDFGYLASKHTSGGRIPTERGYRFYVDSLV
ILYELTLKEKQRIQQEYLKMQFKLDQILKATASVLSSLSNAAGIVIGPAKNLDTLKHIELIHVRGDEILMILVMRSGTVL
HRNIFVDQNYSQEALYQVSKYLNDNLKGYDIYEIQNVIIPKLMIRKDGPEDFIRIADLISSAMTPDNSEVTLYIDGFKNL
YANFRDEEQQLSQVLSLLDDQGFLKAFFSEYIDQDGVFTIIGKDGDRSMSGVSIITSNYKMGEKKIGALGIIGPQRMDYN
RALPLVDFTSKLVSEMVTRISK
>Mature_342_residues
MDLTERHKRILKALVDEFIQENRPVGSKTLFDKHDIGLSPASIRTVLKDLEDFGYLASKHTSGGRIPTERGYRFYVDSLV
ILYELTLKEKQRIQQEYLKMQFKLDQILKATASVLSSLSNAAGIVIGPAKNLDTLKHIELIHVRGDEILMILVMRSGTVL
HRNIFVDQNYSQEALYQVSKYLNDNLKGYDIYEIQNVIIPKLMIRKDGPEDFIRIADLISSAMTPDNSEVTLYIDGFKNL
YANFRDEEQQLSQVLSLLDDQGFLKAFFSEYIDQDGVFTIIGKDGDRSMSGVSIITSNYKMGEKKIGALGIIGPQRMDYN
RALPLVDFTSKLVSEMVTRISK

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 38877; Mature: 38877

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLTERHKRILKALVDEFIQENRPVGSKTLFDKHDIGLSPASIRTVLKDLEDFGYLASKH
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
TSGGRIPTERGYRFYVDSLVILYELTLKEKQRIQQEYLKMQFKLDQILKATASVLSSLSN
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AAGIVIGPAKNLDTLKHIELIHVRGDEILMILVMRSGTVLHRNIFVDQNYSQEALYQVSK
CCEEEEECCCCCCHHHHEEEEEECCCCEEEEEEECCCCEEEEEEEECCCCCHHHHHHHHH
YLNDNLKGYDIYEIQNVIIPKLMIRKDGPEDFIRIADLISSAMTPDNSEVTLYIDGFKNL
HHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHH
YANFRDEEQQLSQVLSLLDDQGFLKAFFSEYIDQDGVFTIIGKDGDRSMSGVSIITSNYK
HHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEECCCC
MGEKKIGALGIIGPQRMDYNRALPLVDFTSKLVSEMVTRISK
CCCHHCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLTERHKRILKALVDEFIQENRPVGSKTLFDKHDIGLSPASIRTVLKDLEDFGYLASKH
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
TSGGRIPTERGYRFYVDSLVILYELTLKEKQRIQQEYLKMQFKLDQILKATASVLSSLSN
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AAGIVIGPAKNLDTLKHIELIHVRGDEILMILVMRSGTVLHRNIFVDQNYSQEALYQVSK
CCEEEEECCCCCCHHHHEEEEEECCCCEEEEEEECCCCEEEEEEEECCCCCHHHHHHHHH
YLNDNLKGYDIYEIQNVIIPKLMIRKDGPEDFIRIADLISSAMTPDNSEVTLYIDGFKNL
HHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHH
YANFRDEEQQLSQVLSLLDDQGFLKAFFSEYIDQDGVFTIIGKDGDRSMSGVSIITSNYK
HHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEEECCCC
MGEKKIGALGIIGPQRMDYNRALPLVDFTSKLVSEMVTRISK
CCCHHCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA